Factors that predict the successful eradication when treating H. pylori infection: Difference between revisions

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{{CMG}}; {{AE}} {{MKK}}, {{SSW}}
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{{Peptic ulcer}}
==2017 ACG Guidelines for factors that predict the successful eradication when treating H. pylori infection==
==2017 ACG Guidelines for factors that predict the successful eradication when treating H. pylori infection==
{| class="wikitable"
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| colspan="1" style="text-align:center; background:LightGreen" |Strong recommendation
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| bgcolor="LightGreen" |1.Bismuth quadruple therapy consisting of a PPI, bismuth, tetracycline, and a nitroimidazole for 10–14 days is a recommended fi rst-line treatment option.
Bismuth quadruple therapy is particularly attractive in patients with any previous macrolide exposure or who are allergic to penicillin
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| bgcolor="LightGreen" |2.Concomitant therapy consisting of a PPI, clarithromycin, amoxicillin and a nitroimidazole for 10–14 days is a recommended fi rst-line treatment option
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{| class="wikitable"  
{| class="wikitable"  
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| colspan="1" style="text-align:center; background:LemonChiffon" |Conditional recommendation
| colspan="1" style="text-align:center; background:LemonChiffon" |Conditional recommendation
|-
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| bgcolor="LemonChiffon" |'''1.'''Patients should be asked about any previous antibiotic exposure(s) and this information should be taken into consideration when choosing an H. pylori
| bgcolor="LemonChiffon" |1.The main determinants of successful [[H. pylori]] eradication are the choice of the regimen, the patient’s adherence to a multi-drug regimen with frequent
treatment regimen '''.'''
side-effects and the sensitivity of the [[H. pylori]] strain to the combination of [[antibiotics]] administered.<ref name="urlwww.nature.com2">{{cite web |url=https://www.nature.com/ajg/journal/v112/n2/pdf/ajg2016563a.pdf |title=www.nature.com |format= |work= |accessdate=}}</ref>
|-
|-
| bgcolor="LemonChiffon" |2.Clarithromycin triple therapy consisting of a PPI, clarithromycin, and amoxicillin or metronidazole for 14 days remains a recommended treatment in regions
|}
where H. pylori clarithromycin resistance is known to be <15% and in patients with no previous history of macrolide exposure for any reason.
|-
| bgcolor="LemonChiffon" |3.Sequential therapy consisting of a PPI and amoxicillin for 5–7 days followed by a PPI, clarithromycin, and a nitroimidazole for 5–7 days is a suggested first line
 
treatment option.
 
|-
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| bgcolor="LemonChiffon" |4.Hybrid therapy consisting of a PPI and amoxicillin for 7 days followed by a PPI, amoxicillin, clarithromycin and a nitroimidazole for 7 days is a suggested


first-line treatment option.
==References==
|-
{{reflist|2}}
| bgcolor="LemonChiffon" |5.Levofloxacin triple therapy consisting of a PPI, levofloxacin, and amoxicillin for 10–14 days is a suggested first-line treatment option.
|-
| bgcolor="LemonChiffon" |6.Fluoroquinolone sequential therapy consisting of a PPI and amoxicillin for 5–7 days followed by a PPI, fluoroquinolone, and nitroimidazole for 5–7 days is a
suggested first-line treatment option.
|}

Latest revision as of 20:38, 12 December 2017


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2], Sargun Singh Walia M.B.B.S.[3]

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2017 ACG Guidelines for factors that predict the successful eradication when treating H. pylori infection

Conditional recommendation
1.The main determinants of successful H. pylori eradication are the choice of the regimen, the patient’s adherence to a multi-drug regimen with frequent

side-effects and the sensitivity of the H. pylori strain to the combination of antibiotics administered.[1]

References

  1. "www.nature.com" (PDF).