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==Overview==
==Overview==
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{{Lipid modifying agents}}
{{Lipid modifying agents}}
{{SIB}}
 
[[Category:Fibrates]]
[[Category:Fibrates]]
[[Category:Prodrugs]]
[[Category:Prodrugs]]

Revision as of 02:26, 9 August 2012

{{drugbox | IUPAC_name = 2-{[2-(4-chlorophenoxy)-2-methylpropanoyl]oxy}ethyl nicotinate | image = Etofibrate svg.png | CAS_number = 31637-97-5 | ATC_prefix = C10 | ATC_suffix = AB09 | PubChem = 65777 | DrugBank = | C=18|H=18|Cl=1|N=1|O=5 | molecular_weight = 363.792 g/mol | bioavailability = | protein_bound = | metabolism = Hydrolyzed to clofibric acid and niacin | elimination_half-life = | excretion = | pregnancy_AU = | pregnancy_US = | pregnancy_category= | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = }}

WikiDoc Resources for Etofibrate

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List of terms related to Etofibrate

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview

Etofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations.[1]

References

  1. Sposito AC, Mansur AP, Maranhão RC, Rodrigues-Sobrinho CR, Coelho OR, Ramires JA (2001). "Etofibrate but not controlled-release niacin decreases LDL cholesterol and lipoprotein (a) in type IIb dyslipidemic subjects". Braz J Med Biol Res. 34 (2): 177–82. PMID 11175492. Free full text

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