Esophageal stricture natural history, complications and prognosis: Difference between revisions

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{{Esophageal stricture}}
{{Esophageal stricture}}


{{CMG}}; {{AE}}  
{{CMG}}; {{AE}} {{MA}}


==Overview==
==Overview==
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
If left untreated, patients with esophageal stricture  may progress to develop [[pulmonary aspiration]], [[weight loss]], and [[dehydration]]. Common [[complication]]<nowiki/>s of esophageal stricture include [[perforation]], [[bleeding]], [[pneumonia]], [[bacteremia]]. [[Prognosis]] is generally good but recurrence of symptoms after [[dilation]] are prevalent and usually recurrent [[dilation]] is necessary.
 
OR
 
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
 
OR
 
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
==Natural History, Complications, and Prognosis==
==Natural History, Complications, and Prognosis==


===Natural History===
===Natural History===
 
* The natural history of [[benign]] esophageal stricture<nowiki/>s starts with gradual [[dysphagia]] to [[solid]] food and [[heartburn]].<ref name="pmid26828759">{{cite journal |vauthors=Repici A, Small AJ, Mendelson A, Jovani M, Correale L, Hassan C, Ridola L, Anderloni A, Ferrara EC, Kochman ML |title=Natural history and management of refractory benign esophageal strictures |journal=Gastrointest. Endosc. |volume=84 |issue=2 |pages=222–8 |year=2016 |pmid=26828759 |doi=10.1016/j.gie.2016.01.053 |url=}}</ref>  
'''Natural history and management of refractory benign esophageal strictures.'''
* In some cases of esophageal stricture, symptoms of [[heartburn]] disappear when [[fibrosis]] is established.<ref name=":0">{{Cite journal|last=Lundell, M.D., Ph.D.|first=Lars|date=|title=Reflux esophagitis and peptic strictures|url=http://www.nature.com/gimo/contents/pt1/full/gimo43.html|journal=GI Motility online|volume=|pages=|via=}}</ref>
 
*If left untreated, patients with esophageal stricture may progress to develop:<ref name="pmid28783923">{{cite journal |vauthors=Hwang JJ |title=Safe and Proper Management of Esophageal Stricture Using Endoscopic Esophageal Dilation |journal=Clin Endosc |volume=50 |issue=4 |pages=309–310 |year=2017 |pmid=28783923 |pmc=5565041 |doi=10.5946/ce.2017.100 |url=}}</ref>  
'''Natural history and management of refractory benign esophageal strictures'''
**[[Pulmonary aspiration]]
 
**[[Weight loss]]
'''Peptic esophageal stricture: is surgery still necessary?'''
**[[Dehydration]]
 
'''Predictor of massive bleeding following stent placement for malignant oesophageal stricture/fistulae: a multicentre study'''
 
'''Complications of esophageal stricture dilation'''
 
'''Over time, the damage caused by stomach acid can scar the lining of the esophagus.When this scar tissue builds up, it makes the esophagus narrow. Called strictures, these narrow spots make it hard to swallow food and drinks, which can lead to weight lossand dehydration. medscape'''
 
'''Refractory Esophageal Strictures: What To Do When Dilation Fails'''
 
Patterns of acid reflux in complicated oesophagitis.https://en.wikibooks.org/wiki/Radiation_Oncology/Toxicity/Esophagus
 
https://en.wikibooks.org/wiki/Radiation_Oncology/Toxicity/Esophagus
* The natural history of benign esophageal strictures starts with gradual dysphagia to solid food and heartburn. <ref name="pmid26828759">{{cite journal |vauthors=Repici A, Small AJ, Mendelson A, Jovani M, Correale L, Hassan C, Ridola L, Anderloni A, Ferrara EC, Kochman ML |title=Natural history and management of refractory benign esophageal strictures |journal=Gastrointest. Endosc. |volume=84 |issue=2 |pages=222–8 |year=2016 |pmid=26828759 |doi=10.1016/j.gie.2016.01.053 |url=}}</ref>  
* In some cases of esophageal stricture, symptoms of heartburn disappear when fibrosis is progressed<ref name=":0">{{Cite journal|last=Lundell, M.D., Ph.D.|first=Lars|date=|title=Reflux esophagitis and peptic strictures|url=http://www.nature.com/gimo/contents/pt1/full/gimo43.html|journal=GI Motility online|volume=|pages=|via=}}</ref>
*If esophageal stricture left untreated, patients may progress to develop pulmonary aspiration, weight loss, and dehydration.<ref name="pmid28783923">{{cite journal |vauthors=Hwang JJ |title=Safe and Proper Management of Esophageal Stricture Using Endoscopic Esophageal Dilation |journal=Clin Endosc |volume=50 |issue=4 |pages=309–310 |year=2017 |pmid=28783923 |pmc=5565041 |doi=10.5946/ce.2017.100 |url=}}</ref>  


===Complications===
===Complications===
*Common complications of esophageal stricture include:<ref name=":1">{{cite journal |vauthors=van Boeckel PG, Siersema PD |title=Refractory esophageal strictures: what to do when dilation fails |journal=Curr Treat Options Gastroenterol |volume=13 |issue=1 |pages=47–58 |year=2015 |pmid=25647687 |pmc=4328110 |doi=10.1007/s11938-014-0043-6 |url=}}</ref>
*Common complications of esophageal stricture include:<ref name=":1">{{cite journal |vauthors=van Boeckel PG, Siersema PD |title=Refractory esophageal strictures: what to do when dilation fails |journal=Curr Treat Options Gastroenterol |volume=13 |issue=1 |pages=47–58 |year=2015 |pmid=25647687 |pmc=4328110 |doi=10.1007/s11938-014-0043-6 |url=}}</ref><ref name="pmid26944699">{{cite journal |vauthors=Liu SY, Xiao P, Li TX, Cao HC, Mao AW, Jiang HS, Cao GS, Liu J, Wang YD, Zhang XS |title=Predictor of massive bleeding following stent placement for malignant oesophageal stricture/fistulae: a multicentre study |journal=Clin Radiol |volume=71 |issue=5 |pages=471–5 |year=2016 |pmid=26944699 |doi=10.1016/j.crad.2016.02.001 |url=}}</ref>
**Perforation
**[[Perforation]]
**Bleeding<ref name="pmid26944699">{{cite journal |vauthors=Liu SY, Xiao P, Li TX, Cao HC, Mao AW, Jiang HS, Cao GS, Liu J, Wang YD, Zhang XS |title=Predictor of massive bleeding following stent placement for malignant oesophageal stricture/fistulae: a multicentre study |journal=Clin Radiol |volume=71 |issue=5 |pages=471–5 |year=2016 |pmid=26944699 |doi=10.1016/j.crad.2016.02.001 |url=}}</ref>  
**[[Bleeding]]
**Pneumonia  
**[[Pneumonia]]
**Bacteremia
**[[Bacteremia]]


===Prognosis===
===Prognosis===
*Prognosis is generally good and it depends what causes esophageal stricture. More than 80-90 % of esophageal strictures respond well to endoscopic dilation <ref name=":1" /> but one third of patients have recurrent symptoms after one year. <ref name="pmid25647687">{{cite journal |vauthors=van Boeckel PG, Siersema PD |title=Refractory esophageal strictures: what to do when dilation fails |journal=Curr Treat Options Gastroenterol |volume=13 |issue=1 |pages=47–58 |year=2015 |pmid=25647687 |pmc=4328110 |doi=10.1007/s11938-014-0043-6 |url=}}</ref>  
*[[Prognosis]] is generally good and depends on the cause of esophageal stricture. More than 80-90% of esophageal stricture<nowiki/>s respond well to [[Endoscopy|endoscopic]] [[dilation]] but one third of patients have recurrent symptoms after one year.<ref name=":1" /><ref name="pmid25647687">{{cite journal |vauthors=van Boeckel PG, Siersema PD |title=Refractory esophageal strictures: what to do when dilation fails |journal=Curr Treat Options Gastroenterol |volume=13 |issue=1 |pages=47–58 |year=2015 |pmid=25647687 |pmc=4328110 |doi=10.1007/s11938-014-0043-6 |url=}}</ref>  
*Weight loss is associated with poor prognosis among patients with esophageal stricture.<ref name="pmid24876933">{{cite journal |vauthors=Berry MF |title=Esophageal cancer: staging system and guidelines for staging and treatment |journal=J Thorac Dis |volume=6 Suppl 3 |issue= |pages=S289–97 |year=2014 |pmid=24876933 |pmc=4037413 |doi=10.3978/j.issn.2072-1439.2014.03.11 |url=}}</ref>
*[[Weight loss]] is associated with poor [[prognosis]] among patients with esophageal stricture.<ref name="pmid24876933">{{cite journal |vauthors=Berry MF |title=Esophageal cancer: staging system and guidelines for staging and treatment |journal=J Thorac Dis |volume=6 Suppl 3 |issue= |pages=S289–97 |year=2014 |pmid=24876933 |pmc=4037413 |doi=10.3978/j.issn.2072-1439.2014.03.11 |url=}}</ref>
*Loss of previous heartburn is related to more esophageal stricture<ref name=":0" />
*Progressive [[gastroesophageal reflux]] may lead to extended esophageal stricture which prevent [[gastric acid]] to flow back in the [[esophagus]]. Loss of previous [[heartburn]] is related to more esophageal stricture.<ref name=":0" />


==References==
==References==
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[[Category:Gastroenterology]]
[[Category:Medicine]]
[[Category:Up-To-Date]]

Latest revision as of 21:41, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]

Overview

If left untreated, patients with esophageal stricture may progress to develop pulmonary aspiration, weight loss, and dehydration. Common complications of esophageal stricture include perforation, bleeding, pneumonia, bacteremia. Prognosis is generally good but recurrence of symptoms after dilation are prevalent and usually recurrent dilation is necessary.

Natural History, Complications, and Prognosis

Natural History

Complications

Prognosis

References

  1. Repici A, Small AJ, Mendelson A, Jovani M, Correale L, Hassan C, Ridola L, Anderloni A, Ferrara EC, Kochman ML (2016). "Natural history and management of refractory benign esophageal strictures". Gastrointest. Endosc. 84 (2): 222–8. doi:10.1016/j.gie.2016.01.053. PMID 26828759.
  2. 2.0 2.1 Lundell, M.D., Ph.D., Lars. "Reflux esophagitis and peptic strictures". GI Motility online.
  3. Hwang JJ (2017). "Safe and Proper Management of Esophageal Stricture Using Endoscopic Esophageal Dilation". Clin Endosc. 50 (4): 309–310. doi:10.5946/ce.2017.100. PMC 5565041. PMID 28783923.
  4. 4.0 4.1 van Boeckel PG, Siersema PD (2015). "Refractory esophageal strictures: what to do when dilation fails". Curr Treat Options Gastroenterol. 13 (1): 47–58. doi:10.1007/s11938-014-0043-6. PMC 4328110. PMID 25647687.
  5. Liu SY, Xiao P, Li TX, Cao HC, Mao AW, Jiang HS, Cao GS, Liu J, Wang YD, Zhang XS (2016). "Predictor of massive bleeding following stent placement for malignant oesophageal stricture/fistulae: a multicentre study". Clin Radiol. 71 (5): 471–5. doi:10.1016/j.crad.2016.02.001. PMID 26944699.
  6. van Boeckel PG, Siersema PD (2015). "Refractory esophageal strictures: what to do when dilation fails". Curr Treat Options Gastroenterol. 13 (1): 47–58. doi:10.1007/s11938-014-0043-6. PMC 4328110. PMID 25647687.
  7. Berry MF (2014). "Esophageal cancer: staging system and guidelines for staging and treatment". J Thorac Dis. 6 Suppl 3: S289–97. doi:10.3978/j.issn.2072-1439.2014.03.11. PMC 4037413. PMID 24876933.

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