Escherichia coli enteritis classification: Difference between revisions

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==Overview==
==Overview==
 
[[Escherichia coli enteritis|''E. coli'' enteritis]] may be classified according to the ''[[Escherichia coli|E. coli]]'' [[species]] into [[Enterotoxigenic E. coli|Enterotoxigenic ''E. coli''  (ETEC)]], [[Enteropathogenic E. coli|Enteropathogenic ''E. coli'' (EPEC)]], [[Enterohemorrhagic escherichica coli|Enterohemorrhagic ''E. coli'' (EHEC)]], [[Enteroinvasive E. coli|Enteroinvasive ''E. coli'' (EIEC)]], and [[Enteroaggressive E. coli|Enteroaggressive ''E. coli'' (EAEC)]].
==Classification==
==Classification==
''E. coli'' enteritis may be classified according to the ''E. coli'' strain pathogenesis into the following:
[[Escherichia coli enteritis|''E. coli'' enteritis]] may be classified according to the involved ''[[Escherichia coli|E. coli]]'' [[species]] listed as follows[[Enterotoxigenic Escherichia coli|:]]
*Enteropathogenic
*[[Enterotoxigenic Escherichia coli|Enterotoxigenic ''E. coli'' (ETEC)]]
*Enterotoxicogenic
*[[Enteropathogenic E. coli|Enteropathogenic ''E. coli'' (EPEC)]] (including diffusely adherent ''[[Escherichia coli|E. coli]]'' [DAEC], a subtype of [[Enteropathogenic E. coli|EPEC]])
*Enteroinvasive
*[[Enterohemorrhagic escherichica coli|Enterohemorrhagic ''E. coli'' (EHEC)]] (may be [[Shiga-like toxin]] producing or [[Verotoxin-producing Escherichia coli|Verotoxin]]-producing)
 
*[[Enteroinvasive E. coli|Enteroinvasive ''E. coli'' (EIEC)]]
The following table shows the distinguishing features between the strains and pathophysiological mechanisms of of ''E. coli'':
*[[Enteroaggressive E. coli|Enteroaggressive ''E. coli'' (EAEC)]]


The following table demonstrates the distinguishing clinical features and [[Pathophysiology|pathophysiological]] [[Mechanism (biology)|mechanisms]] of various enteritis-causing ''[[Escherichia coli|E. coli]]'' [[Strain (biology)|strains]]:
{| {{table}} cellpadding="4" cellspacing="0" style="border:#c9c9c9 1px solid; margin: 1em 1em 1em 0; border-collapse: collapse;"
| align="center" style="background:#4479BA; color: #FFFFFF;" + |'''Properties/Symptoms'''
| align="center" style="background:#4479BA; color: #FFFFFF;" + |'''ETEC'''
| align="center" style="background:#4479BA; color: #FFFFFF;" + |'''EPEC'''
| align="center" style="background:#4479BA; color: #FFFFFF;" + |'''EHEC<br><sup>(STEC or VTEC)</sup>'''
| align="center" style="background:#4479BA; color: #FFFFFF;" + |'''EIEC'''
|-
| [[Toxin]]||LT/ST<sup>a</sup>||-||[[Shiga-like toxin|Shiga]] or [[Verotoxin|Vero]] [[toxin]]||-
|-
| Invasive||-||-||-||+
|-
| Intimin||-||+||+||-
|-
| Enterohemolysin||-||-||+||-
|-
| [[Human feces|Stool]]||[[Diarrhea|Watery]]||[[Diarrhea|Watery]], [[Dysentery|Bloody]]||[[Diarrhea|Watery]], [[Dysentery|very bloody]]||[[Mucus|Mucoid]], [[Dysentery|bloody]]
|-
| [[Fever]]||Low||+||-||+
|-
| [[Feces|Fecal]] [[White blood cells|leukocytes]]||-||-||-||+
|-
| [[Intestine]] involved||[[Small intestine|Small]]||[[Small intestine|Small]]||[[Colon (anatomy)|Colon]]||[[Colon (anatomy)|Colon]], [[Small intestine|lower small]]
|-
| [[Serology]]||Various||O26, O111 & others||O157:H7, O26, O111 & others||Various
|-
| ID<sup>b</sup>||High||High||Low||High
|}
<sup>a=LT, labile toxin; ST, stable toxin; b=ID, infective dose.<br>
Adapted from Food and Drug Administration (FDA) - Bacteriological Analytical Manual Chapter 4A - Diarrheagenic ''Escherichia coli''.<ref name="FDA">{{cite web |url=http://www.fda.gov/Food/FoodScienceResearch/LaboratoryMethods/ucm070080.htm |title=Bacteriological Analytical Manual Chapter 4A - Diarrheagenic Escherichia coli |last1=Feng |first1=Peter |last2= Weagant|first2=Stephen D. | last3=Jinneman|first3=Karen|date=February 2011 |website=www.fda.gov |publisher=Food and Drug Administration |access-date=December 19 2015}}</ref>


==References==
==References==
{{reflist|2}}
{{reflist|2}}


[[Category:Infectious disease]]
[[Category:Disease]]
[[Category:Gastroenterology]]
[[Category:Foodborne illnesses]]
[[Category:Emergency medicine]]
[[Category:Bacterial diseases]]

Latest revision as of 01:04, 17 December 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Serge Korjian M.D., Yazan Daaboul, M.D.

Overview

E. coli enteritis may be classified according to the E. coli species into Enterotoxigenic E. coli (ETEC), Enteropathogenic E. coli (EPEC), Enterohemorrhagic E. coli (EHEC), Enteroinvasive E. coli (EIEC), and Enteroaggressive E. coli (EAEC).

Classification

E. coli enteritis may be classified according to the involved E. coli species listed as follows:

The following table demonstrates the distinguishing clinical features and pathophysiological mechanisms of various enteritis-causing E. coli strains:

Properties/Symptoms ETEC EPEC EHEC
(STEC or VTEC)
EIEC
Toxin LT/STa - Shiga or Vero toxin -
Invasive - - - +
Intimin - + + -
Enterohemolysin - - + -
Stool Watery Watery, Bloody Watery, very bloody Mucoid, bloody
Fever Low + - +
Fecal leukocytes - - - +
Intestine involved Small Small Colon Colon, lower small
Serology Various O26, O111 & others O157:H7, O26, O111 & others Various
IDb High High Low High

a=LT, labile toxin; ST, stable toxin; b=ID, infective dose.
Adapted from Food and Drug Administration (FDA) - Bacteriological Analytical Manual Chapter 4A - Diarrheagenic Escherichia coli.[1]

References

  1. Feng, Peter; Weagant, Stephen D.; Jinneman, Karen (February 2011). "Bacteriological Analytical Manual Chapter 4A - Diarrheagenic Escherichia coli". www.fda.gov. Food and Drug Administration. Retrieved December 19 2015. Check date values in: |access-date= (help)