Eosinophilic esophagitis (patient information): Difference between revisions

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==Overview==
==Overview==
Esophagitis is a general term for any inflammation, irritation, or swelling of the esophagus, the tube that leads from the back of the mouth to the stomach.


==What are the Symptoms of (Disease name)?==
==What are the Symptoms of (Disease name)?==
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==Who is at Highest Risk?==
==Who is at Highest Risk?==
 
*The risk factors of EoE are as follows
*Common in both children and adults,
*Male gender
*Cold and dry climate
*EoE is common in people with a history of European ancestry
*Summer and fall
*Positive family history of EoE
*History of allergies such as asthma, industrial exposures, environmental allergies, chronic respiratory disease, food allergies and atopic dermatitis.


==Diagnosis==
==Diagnosis==
*There are no specific diagnostic markers to diagnose the EoE patients.
*Although not specific, elevated serum IgE levels are identified in majority patients.
*An increased peripheral eosinophil count is also seen in majority patients.
*There are 3 main ways in which food allergies can be detected in EE are Skin prick testing, Blood allergy testing, Atopy patch testing.
*The barium swallow of the esophagus shows multiple rings associated with eosinophilic esophagitis.
*There are no MRI or CT scan findings associated with EoE. however, an MRI or a CT scan may be helpful in the diagnosis of complications of EoE such as tears, perforation strictures etc


==When to Seek Urgent Medical Care?==
==When to Seek Urgent Medical Care?==
*Patients should seek medical care where they have the following symptoms
* Difficulty swallowing
* Reappearance of ingested food in the mouth
* Cough
* Chest pain
* Food impaction
* Abdominal pain
* Vomiting
* Nausea


==Treatment Options==
==Treatment Options==
*The optimal treatment of [[eosinophilic esophagitis]] remains uncertain. 
*An eight-week course of therapy with [[topical]] [[corticosteroids]] ([[fluticasone]] or [[budesonide]]) may be used as the first-line [[Pharmacology|pharmacologic]] therapy. 
*[[Allergen]] elimination usually leads to improvement in [[dysphagia]] and reduction of [[eosinophil]] infiltration. 
*[[Esophageal]] [[dilation]] of is generally reserved for [[refractory]] cases with [[esophageal stricture]].


==Where to find Medical Care for (Disease name)?==
==Where to find Medical Care for (Disease name)?==
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==What to Expect (Outlook/Prognosis)?==
==What to Expect (Outlook/Prognosis)?==
*The prognosis of the EoE is as follows:
*EoE is a relatively newly recognized disease, there is very limited data on the causes, natural history, prognosis, diagnosis, and management of these patients.
*The long-term prognosis of the EoE is unclear but patients diagnosed with EoE have an unaffected lifespan.
*Patients should be counseled that although it is a chronic disease, it is a benign condition.
*Patients who are untreated or have discontinued the treatment have progression of their symptoms.
*The EoE patients with a narrow esophageal lumen are resistant to the corticosteroid treatment and require many esophageal endoscopic procedures..
*The dysphagia is common in patients with increased eosinophil count in the blood.
*The EoE is restricted only to the esophagus sparing the stomach and the duodenum.
*A common concern for the patient and their families is what is the chance of that EoE may progress to a malignancy if untreated, EoE does not progress into metaplasia or dysplasia or esophageal cancer.


==Possible Complications==
==Possible Complications==
*The [[complications]] of the [[EoE]] are as follows:
*[[Scarring]] of [[esophagus]]-leading to [[dysphagia]]
*[[Esophageal]] [[stenosis]]- causing food stuck
*[[Tears]] or [[perforation]] during the [[endoscopy]] or [[retching]] leading to [[boerhaave syndrome]


==Sources==
==Sources==
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Latest revision as of 15:20, 20 December 2017

Eosinophilic esophagitis

Overview

What are the symptoms?

What are the causes?

Who is at highest risk?

Diagnosis

When to seek urgent medical care?

Treatment options

Where to find medical care for Eosinophilic esophagitis?

Prevention

What to expect (Outlook/Prognosis)?

Possible complications

Eosinophilic esophagitisOn the Web

Ongoing Trials at Clinical Trials.gov

Images of Eosinophilic esophagitis

Videos on Eosinophilic esophagitis

FDA on Eosinophilic esophagitis

CDC on Eosinophilic esophagitis

Eosinophilic esophagitisin the news

Blogs on Eosinophilic esophagitis

Directions to Hospitals Treating Eosinophilic esophagitis

Risk calculators and risk factors for Eosinophilic esophagitis

For the WikiDoc page for this topic, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Esophagitis is a general term for any inflammation, irritation, or swelling of the esophagus, the tube that leads from the back of the mouth to the stomach.

What are the Symptoms of (Disease name)?

The symptoms of the eosinophilic esophagitis are as follows:

  • Difficulty swallowing
  • Reappearance of ingested food in the mouth
  • Cough
  • Chest pain
  • Food impaction
  • Abdominal pain
  • Vomiting
  • Nausea

What Causes (disease name)?

  • The causes of EoE are the food and pollen react with the lining of the esophagus, these allergens cause the multiplication of eosinophils in the layers of the esophagus and produce a protein that causes inflammation.
  • The inflammation further cause scarring, excessive fibrous tissue deposition over the lining of the esophagus eventually leading to difficulty in swallowing.
  • The difficulty in swallowing can sometimes worsen to cause food impaction and additional symptoms such as chest pain.

Who is at Highest Risk?

  • The risk factors of EoE are as follows
  • Common in both children and adults,
  • Male gender
  • Cold and dry climate
  • EoE is common in people with a history of European ancestry
  • Summer and fall
  • Positive family history of EoE
  • History of allergies such as asthma, industrial exposures, environmental allergies, chronic respiratory disease, food allergies and atopic dermatitis.

Diagnosis

  • There are no specific diagnostic markers to diagnose the EoE patients.
  • Although not specific, elevated serum IgE levels are identified in majority patients.
  • An increased peripheral eosinophil count is also seen in majority patients.
  • There are 3 main ways in which food allergies can be detected in EE are Skin prick testing, Blood allergy testing, Atopy patch testing.
  • The barium swallow of the esophagus shows multiple rings associated with eosinophilic esophagitis.
  • There are no MRI or CT scan findings associated with EoE. however, an MRI or a CT scan may be helpful in the diagnosis of complications of EoE such as tears, perforation strictures etc

When to Seek Urgent Medical Care?

  • Patients should seek medical care where they have the following symptoms
  • Difficulty swallowing
  • Reappearance of ingested food in the mouth
  • Cough
  • Chest pain
  • Food impaction
  • Abdominal pain
  • Vomiting
  • Nausea

Treatment Options

Where to find Medical Care for (Disease name)?

Medical care for (disease name) can be found here.

Prevention

What to Expect (Outlook/Prognosis)?

  • The prognosis of the EoE is as follows:
  • EoE is a relatively newly recognized disease, there is very limited data on the causes, natural history, prognosis, diagnosis, and management of these patients.
  • The long-term prognosis of the EoE is unclear but patients diagnosed with EoE have an unaffected lifespan.
  • Patients should be counseled that although it is a chronic disease, it is a benign condition.
  • Patients who are untreated or have discontinued the treatment have progression of their symptoms.
  • The EoE patients with a narrow esophageal lumen are resistant to the corticosteroid treatment and require many esophageal endoscopic procedures..
  • The dysphagia is common in patients with increased eosinophil count in the blood.
  • The EoE is restricted only to the esophagus sparing the stomach and the duodenum.
  • A common concern for the patient and their families is what is the chance of that EoE may progress to a malignancy if untreated, EoE does not progress into metaplasia or dysplasia or esophageal cancer.

Possible Complications

Sources

http://www.nlm.nih.gov/medlineplus/ency/article/000434.htm


Template:WH Template:WS