Enflurane

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Enflurane
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [2]

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Overview

Enflurane is a general anesthetic that is FDA approved for the {{{indicationType}}} of analgesia for labor/delivery, For vaginal delivery, anesthesia - obstetric procedure, as supplement to other general anesthetic agents during cesarean section, general anesthesia.. Common adverse reactions include gastrointestinal: nausea, vomiting, musculoskeletal: involuntary movement, neurologic: shivering.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

  • Analgesia for labor/delivery, for vaginal delivery: for vaginal delivery, 0.25 to 1% concentration.
  • Anesthesia - Obstetric procedure, As supplement to other general anesthetic agents during Cesarean section: during cesarean section, 0.5 to 1% concentration (to supplement other anesthetics).
  • General anesthesia: induction, 2 to 4.5% concentration via vaporizer; with oxygen or combination with oxygen-nitrous oxide mixtures.
  • General anesthesia: maintenance, 0.5 to 3% concentration; MAX 3%

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

  • General anesthesia - Surgical procedure on eye proper

Non–Guideline-Supported Use

There is limited information about Off-Label Non–Guideline-Supported Use of Enflurane in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

There is limited information regarding Enflurane FDA-Labeled Indications and Dosage (Pediatric) in the drug label.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information about Off-Label Guideline-Supported Use of Enflurane in pediatric patients.

Non–Guideline-Supported Use

There is limited information about Off-Label Non–Guideline-Supported Use of Enflurane in pediatric patients.

Contraindications

Seizure disorders (see WARNINGS) Known sensitivity to Enflurane or other halogenated anestheticsKnown or suspected genetic susceptibility to malignant hyperthermia

Warnings

There is limited information regarding Enflurane Warnings' in the drug label.

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Enflurane Clinical Trials Experience in the drug label.

Postmarketing Experience

There is limited information regarding Enflurane Postmarketing Experience in the drug label.

Drug Interactions

There is limited information regarding Enflurane Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA): There is no FDA guidance on usage of Enflurane in women who are pregnant.
Pregnancy Category (AUS): There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Enflurane in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Enflurane during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Enflurane in women who are nursing.

Pediatric Use

There is no FDA guidance on the use of Enflurane in pediatric settings.

Geriatic Use

There is no FDA guidance on the use of Enflurane in geriatric settings.

Gender

There is no FDA guidance on the use of Enflurane with respect to specific gender populations.

Race

There is no FDA guidance on the use of Enflurane with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Enflurane in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Enflurane in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Enflurane in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Enflurane in patients who are immunocompromised.

Administration and Monitoring

Administration

There is limited information regarding Enflurane Administration in the drug label.

Monitoring

There is limited information regarding Enflurane Monitoring in the drug label.

IV Compatibility

There is limited information regarding the compatibility of Enflurane and IV administrations.

Overdosage

There is limited information regarding Enflurane overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

Pharmacology

There is limited information regarding Enflurane Pharmacology in the drug label.

Mechanism of Action

There is limited information regarding Enflurane Mechanism of Action in the drug label.

Structure

There is limited information regarding Enflurane Structure in the drug label.

Pharmacodynamics

There is limited information regarding Enflurane Pharmacodynamics in the drug label.

Pharmacokinetics

There is limited information regarding Enflurane Pharmacokinetics in the drug label.

Nonclinical Toxicology

There is limited information regarding Enflurane Nonclinical Toxicology in the drug label.

Clinical Studies

There is limited information regarding Enflurane Clinical Studies in the drug label.

How Supplied

There is limited information regarding Enflurane How Supplied in the drug label.

Storage

There is limited information regarding Enflurane Storage in the drug label.

Images

Drug Images

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Package and Label Display Panel

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Patient Counseling Information

There is limited information regarding Enflurane Patient Counseling Information in the drug label.

Precautions with Alcohol

Alcohol-Enflurane interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

There is limited information regarding Enflurane Brand Names in the drug label.

Look-Alike Drug Names

There is limited information regarding Enflurane Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.