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==Overview==
==Overview==
Endometriosis is a condition affecting females in the reproductive age group. It has a wide spectrum of presentations, it can be asymptomatic or present with premenstrual spotting and cyclical abdominal pain or present with infertility or chronic pelvic pain or as deep endometriosis presenting with dyspareunia, dyschezia and cyclical rectal bleeding. Complications of endometriosis include infertility, fibrosis, chocolate cyst, and rarely affecting other organs such as lung.
[[Endometriosis]] is a condition affecting [[females]] in the reproductive age group. It has a wide spectrum of presentations, it can be asymptomatic or present with premenstrual spotting and cyclical [[abdominal pain]] or present with [[infertility]] or chronic pelvic pain or as deep [[endometriosis]] presenting with [[dyspareunia]], [[dyschezia]] and cyclical [[rectal bleeding]]. Complications of [[endometriosis]] include [[infertility]], [[fibrosis]], [[Chocolate cyst of the ovary|chocolate cyst]], and rarely affecting other organs such as [[lung]].


==Natural History, Complications and Prognosis==
==Natural History, Complications and Prognosis==
===Natural History===
===Natural History===
Endometriosis is a condition affecting females in the reproductive age group. It has a wide spectrum of presentations, it can be asymptomatic or present with premenstrual spotting and cyclical abdominal pain or present with infertility or chronic pelvic pain or as deep endometriosis presenting with dyspareunia, dyschezia and cyclical rectal bleeding. The progression of the disease is variable, it can progress to a severe disease or regress or remain the same. Severe disease is called as deep endometriosis and presents with chronic pelvic pain and infertility other complications due to the extensive fibrosis of the pelvic structures.<ref name="pmid19947450">{{cite journal| author=Wenger JM, Loubeyre P, Marci R, Dubuisson JB| title=[Endometriosis: review of the literature and clinical management]. | journal=Rev Med Suisse | year= 2009 | volume= 5 | issue= 222 | pages= 2085-6, 2088-90 | pmid=19947450 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19947450  }} </ref><ref name="pmid24920437">{{cite journal| author=Brawn J, Morotti M, Zondervan KT, Becker CM, Vincent K| title=Central changes associated with chronic pelvic pain and endometriosis. | journal=Hum Reprod Update | year= 2014 | volume= 20 | issue= 5 | pages= 737-47 | pmid=24920437 | doi=10.1093/humupd/dmu025 | pmc=4501205 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24920437  }} </ref>
[[Endometriosis]] is a condition affecting females in the reproductive age group. It has a wide spectrum of presentations, it can be asymptomatic or present with premenstrual spotting and cyclical [[abdominal pain]] or present with [[infertility]] or chronic pelvic pain or as deep [[endometriosis]] presenting with [[dyspareunia]], [[dyschezia]] and cyclical [[rectal bleeding]]. The progression of the disease if left untreated, is variable, it can progress to a severe disease or regress or remain the same. Severe disease is called as deep endometriosis and presents with chronic pelvic pain and [[infertility]] other complications due to the extensive [[fibrosis]] of the pelvic structures.<ref name="pmid19947450">{{cite journal| author=Wenger JM, Loubeyre P, Marci R, Dubuisson JB| title=[Endometriosis: review of the literature and clinical management]. | journal=Rev Med Suisse | year= 2009 | volume= 5 | issue= 222 | pages= 2085-6, 2088-90 | pmid=19947450 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19947450  }} </ref><ref name="pmid24920437">{{cite journal| author=Brawn J, Morotti M, Zondervan KT, Becker CM, Vincent K| title=Central changes associated with chronic pelvic pain and endometriosis. | journal=Hum Reprod Update | year= 2014 | volume= 20 | issue= 5 | pages= 737-47 | pmid=24920437 | doi=10.1093/humupd/dmu025 | pmc=4501205 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24920437  }} </ref>


===Complications===
===Complications===
The main complication of endometriosis is infertility and accounts for 17% of cases with infertility. Other common complications include:<ref name="pmid26837776">{{cite journal| author=Donnez J, Donnez O, Orellana R, Binda MM, Dolmans MM| title=Endometriosis and infertility. | journal=Panminerva Med | year= 2016 | volume= 58 | issue= 2 | pages= 143-50 | pmid=26837776 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26837776  }} </ref><ref name="pmid26315050">{{cite journal| author=Karaman Y, Uslu H| title=Complications and their management in endometriosis surgery. | journal=Womens Health (Lond) | year= 2015 | volume= 11 | issue= 5 | pages= 685-92 | pmid=26315050 | doi=10.2217/whe.15.55 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26315050  }} </ref>
The major complication of [[endometriosis]] is [[infertility]] and accounts for 17% of cases with [[infertility]]. Other common complications include:<ref name="pmid26837776">{{cite journal| author=Donnez J, Donnez O, Orellana R, Binda MM, Dolmans MM| title=Endometriosis and infertility. | journal=Panminerva Med | year= 2016 | volume= 58 | issue= 2 | pages= 143-50 | pmid=26837776 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26837776  }} </ref><ref name="pmid26315050">{{cite journal| author=Karaman Y, Uslu H| title=Complications and their management in endometriosis surgery. | journal=Womens Health (Lond) | year= 2015 | volume= 11 | issue= 5 | pages= 685-92 | pmid=26315050 | doi=10.2217/whe.15.55 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26315050  }} </ref>
* Internal scarring
* Internal scarring
* Adhesions
* [[Adhesions]]
* Pelvic cysts
* Pelvic cysts
* Chocolate cysts
* [[Chocolate cyst of the ovary|Chocolate cyst]]<nowiki/>s
* Ruptured cyst
* Ruptured cyst
*Less common complications include bowel and ureteral obstruction resulting from pelvic adhesions.
*Less common complications include bowel and [[ureteral obstruction]] resulting from [[Adhesions|pelvic adhesions]].


===Prognosis===
===Prognosis===
Prognosis of endometriosis is variable with medical therapy, majority of the patients improve with medical therapy but the symptoms recur in 30 to 40% of patients once the treatment is stopped.<ref name="pmid26450609">{{cite journal| author=Leone Roberti Maggiore U, Ferrero S, Mangili G, Bergamini A, Inversetti A, Giorgione V et al.| title=A systematic review on endometriosis during pregnancy: diagnosis, misdiagnosis, complications and outcomes. | journal=Hum Reprod Update | year= 2016 | volume= 22 | issue= 1 | pages= 70-103 | pmid=26450609 | doi=10.1093/humupd/dmv045 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26450609  }} </ref>
Prognosis of [[endometriosis]] is variable with medical therapy, majority of the patients improve with medical therapy but the symptoms recur in 30 to 40% of patients after completion of treatment.<ref name="pmid26450609">{{cite journal| author=Leone Roberti Maggiore U, Ferrero S, Mangili G, Bergamini A, Inversetti A, Giorgione V et al.| title=A systematic review on endometriosis during pregnancy: diagnosis, misdiagnosis, complications and outcomes. | journal=Hum Reprod Update | year= 2016 | volume= 22 | issue= 1 | pages= 70-103 | pmid=26450609 | doi=10.1093/humupd/dmv045 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26450609  }} </ref>


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Revision as of 15:11, 20 June 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Kuchkuntla, M.B.B.S[2]

Overview

Endometriosis is a condition affecting females in the reproductive age group. It has a wide spectrum of presentations, it can be asymptomatic or present with premenstrual spotting and cyclical abdominal pain or present with infertility or chronic pelvic pain or as deep endometriosis presenting with dyspareunia, dyschezia and cyclical rectal bleeding. Complications of endometriosis include infertility, fibrosis, chocolate cyst, and rarely affecting other organs such as lung.

Natural History, Complications and Prognosis

Natural History

Endometriosis is a condition affecting females in the reproductive age group. It has a wide spectrum of presentations, it can be asymptomatic or present with premenstrual spotting and cyclical abdominal pain or present with infertility or chronic pelvic pain or as deep endometriosis presenting with dyspareunia, dyschezia and cyclical rectal bleeding. The progression of the disease if left untreated, is variable, it can progress to a severe disease or regress or remain the same. Severe disease is called as deep endometriosis and presents with chronic pelvic pain and infertility other complications due to the extensive fibrosis of the pelvic structures.[1][2]

Complications

The major complication of endometriosis is infertility and accounts for 17% of cases with infertility. Other common complications include:[3][4]

Prognosis

Prognosis of endometriosis is variable with medical therapy, majority of the patients improve with medical therapy but the symptoms recur in 30 to 40% of patients after completion of treatment.[5]

References

  1. Wenger JM, Loubeyre P, Marci R, Dubuisson JB (2009). "[Endometriosis: review of the literature and clinical management]". Rev Med Suisse. 5 (222): 2085–6, 2088–90. PMID 19947450.
  2. Brawn J, Morotti M, Zondervan KT, Becker CM, Vincent K (2014). "Central changes associated with chronic pelvic pain and endometriosis". Hum Reprod Update. 20 (5): 737–47. doi:10.1093/humupd/dmu025. PMC 4501205. PMID 24920437.
  3. Donnez J, Donnez O, Orellana R, Binda MM, Dolmans MM (2016). "Endometriosis and infertility". Panminerva Med. 58 (2): 143–50. PMID 26837776.
  4. Karaman Y, Uslu H (2015). "Complications and their management in endometriosis surgery". Womens Health (Lond). 11 (5): 685–92. doi:10.2217/whe.15.55. PMID 26315050.
  5. Leone Roberti Maggiore U, Ferrero S, Mangili G, Bergamini A, Inversetti A, Giorgione V; et al. (2016). "A systematic review on endometriosis during pregnancy: diagnosis, misdiagnosis, complications and outcomes". Hum Reprod Update. 22 (1): 70–103. doi:10.1093/humupd/dmv045. PMID 26450609.