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<small>'''''Synonyms / Brand Names:''''' </small>
{{Drugbox
| verifiedrevid = 443722856
| IUPAC_name = 4-methoxy-''N''-[2-(1-methyl-2-piperidin-1-ylethyl)phenyl]benzamide
| image = Encainide.png


{{CMG}}
<!--Clinical data-->
| tradename = Enkaid
| Drugs.com = {{drugs.com|CONS|encainide}}
| MedlinePlus = a605040
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US = <!-- A / B / C / D / X -->
| pregnancy_category = 
| legal_AU = <!-- Unscheduled / S2 / S4 / S8 -->
| legal_UK = <!-- GSL / P / POM / CD -->
| legal_US = <!-- OTC / Rx-only -->
| legal_status = Withdrawn
| routes_of_administration =


==Dosing and Administration==
<!--Pharmacokinetic data-->
<br>
| bioavailability =  
----
| protein_bound =  
<br>
| metabolism =  
<font size="4">
| elimination_half-life =  
[[{{PAGENAME}}#FDA Package Insert Resources|FDA Package Insert Resources]]
| excretion =  
<br></font size><small>Indications, Contraindications, Side Effects, Drug Interactions, etc.</small><font size="4"><br>
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[[{{PAGENAME}}#Publication Resources|Publication Resources]]
<br></font size><small>Recent articles, WikiDoc State of the Art Review, Textbook Information</small><font size="4"><br>
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[[{{PAGENAME}}#Trial Resources|Trial Resources]]
<br></font size><small>Ongoing Trials, Trial Results</small><font size="4"><br>
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[[{{PAGENAME}}#Guidelines & Evidence Based Medicine Resources|Guidelines & Evidence Based Medicine Resources]]
<br></font size><small>US National Guidelines, Cochrane Collaboration, etc.</small><font size="4"><br>
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[[{{PAGENAME}}#Media Resources|Media Resources]]
<br></font size><small>Slides, Video, Images, MP3, Podcasts, etc.</small><font size="4"><br><br>
[[{{PAGENAME}}#Patient Resources|Patient Resources]]
<br></font size><small>Discussion Groups, Handouts, Blogs, News, etc.</small><font size="4"><br>
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[[{{PAGENAME}}#International Resources|International Resources]]
<br></font size><small>en Español</small><font size="4"><br>
<br>
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==FDA Package Insert Resources==
<!--Identifiers-->
[[{{PAGENAME}} indications|Indications]]
| CAS_number = 66778-36-7
<br>
| ATC_prefix = C01
<br>
| ATC_suffix = BC08
[[{{PAGENAME}} contraindications|Contraindications]]
| ATC_supplemental =
<br>
| PubChem = 48041
<br>
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
[[{{PAGENAME}} side effects|Side Effects]]
| DrugBank = DB01228
<br>
| ChEMBL = 315838
<br>
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
[[{{PAGENAME}} drug interactions|Drug Interactions]]
| ChemSpiderID = 43697
<br>
| UNII_Ref = {{fdacite|correct|FDA}}
<br>
| UNII = SY3J0147NB
[[{{PAGENAME}} precautions|Precautions]]
| KEGG_Ref = {{keggcite|correct|kegg}}
<br>
| KEGG = D07894
<br>
| ChEBI_Ref = {{ebicite|correct|EBI}}
[[{{PAGENAME}} overdose|Overdose]]
| ChEBI = 4788
<br>
<br>
[[{{PAGENAME}} instructions for administration|Instructions for Administration]]
<br>
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[[{{PAGENAME}} how supplied|How Supplied]]
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[[{{PAGENAME}} pharmacokinetics and molecular data|Pharmacokinetics and Molecular Data]]
<br>
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[FDA label]
<br>
<br>
[http://google2.fda.gov/search?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&x=0&y=0&client=FDA&site=FDA&lr=&proxystylesheet=FDA&output=xml_no_dtd&getfields=* FDA on {{PAGENAME}}]
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</font size><small>[[{{PAGENAME}}#Dosing and Administration|Return to top]]</small><font size="4">
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==Publication Resources==
<!--Chemical data-->
[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}} Most Recent Articles on {{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}]
| C=22 | H=28 | N=2 | O=2
<br>
| molecular_weight = 352.47 g/mol
<br>
| smiles = CC(CN1CCCCC1)c3ccccc3NC(=O)c2ccc(OC)cc2
[http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}%20AND%20systematic%5Bsb%5D  Review Articles on {{PAGENAME}}]
| InChI = 1/C22H28N2O2/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(25)18-11-14-20(26-2)15-12-18/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,16H2,1-2H3,(H,23,25)
<br>
| InChIKey = PJWPNDMDCLXCOM-UHFFFAOYAR
<br>
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+AND+%28%28N+Engl+J+Med%5Bta%5D%29+OR+%28Lancet%5Bta%5D%29+OR+%28BMJ%5Bta%5D%29%29 Articles on {{PAGENAME}} in N Eng J Med, Lancet, BMJ]
| StdInChI = 1S/C22H28N2O2/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(25)18-11-14-20(26-2)15-12-18/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,16H2,1-2H3,(H,23,25)
<br>
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
<br>
| StdInChIKey = PJWPNDMDCLXCOM-UHFFFAOYSA-N
[[Encainide detailed information|WikiDoc State of the Art Review]]
}}
<br>
__NOTOC__
<br>
{{SI}}
[http://books.google.com/books?ie=UTF-8&oe=utf-8&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&qt_s=Search&sa=N&tab=gp Textbook Information on {{PAGENAME}}]
{{CMG}}
<br>
<br>
</font size><small>[[{{PAGENAME}}#Dosing and Administration|Return to top]]</small><font size="4">
<br>
<br>
 
==Trial Resources==
[http://clinicaltrials.gov/search/open/condition={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}} Ongoing Trials with {{PAGENAME}} at Clinical Trials.gov]
<br>
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+AND+%28randomized+controlled+trial%5BPublication+Type%5D+OR+%28randomized%5BTitle%2FAbstract%5D+AND+controlled%5BTitle%2FAbstract%5D+AND+trial%5BTitle%2FAbstract%5D%29%29 Trial Results with {{PAGENAME}}]
<br>
<br>
</font size><small>[[{{PAGENAME}}#Dosing and Administration|Return to top]]</small><font size="4">
<br>
<br>


==Guidelines & Evidence Based Medicine Resources==
==Overview==
[http://www.guideline.gov/search/searchresults.aspx?Type=3&txtSearch={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&num=20 US National Guidelines Clearinghouse on {{PAGENAME}}]
'''Encainide''' (trade name '''Enkaid''') is a class Ic [[antiarrhythmic agent]]. It is no longer used because of its frequent [[proarrhythmic]] side effects.<ref>{{cite pmid|1900101}}</ref>
<br>
<br>
[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:({{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}) AND (Cochrane Database Syst Rev[ta])}} Cochrane Collaboration on {{PAGENAME}}]
<br>
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:({{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}) AND (Cost effectiveness)}} Cost Effectiveness of {{PAGENAME}}]
<br>
<br>
</font size><small>[[{{PAGENAME}}#Dosing and Administration|Return to top]]</small><font size="4">
<br>
<br>
==Media Resources==
[http://www.google.com/search?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+ppt&ie=utf-8&oe=utf-8&aq=t&rls=org.mozilla:en-US:official&client=firefox-a Powerpoint Slides on {{PAGENAME}}]
<br>
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[http://images.google.com/images?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&sa=N&tab=wi Images of {{PAGENAME}}]
<br>
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[http://www.google.com/search?hl=en&client=firefox-a&rls=org.mozilla%3Aen-US%3Aofficial&hs=hPo&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+podcasts+OR+MP3&btnG=Search Podcasts & MP3s on {{PAGENAME}}]
<br>
<br>
[http://video.google.com/videosearch?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&um=1&sa=N&tab=fv# Videos on {{PAGENAME}}]
<br>
<br>
</font size><small>[[{{PAGENAME}}#Dosing and Administration|Return to top]]</small><font size="4">
<br>
<br>


==Patient Resources==
==References==
[[{{PAGENAME}} (patient information)|Patient Information from National Library of Medicine]]
{{reflist|2}}
<br>
<br>
[http://www.google.com/search?hl=en&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+more:for_patients&cx=disease_for_patients&sa=N&oi=cooptsr&resnum=0&ct=col3&cd=1  Patient Resources on {{PAGENAME}}]
<br>
<br>
[http://groups.google.com/groups/search?ie=UTF-8&oe=utf-8&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&qt_s=Search Discussion Groups on {{PAGENAME}}]
<br>
<br>
[http://www.google.com/search?hl=en&client=firefox-a&rls=org.mozilla:en-US:official&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+more:patient_handouts&cx=disease_for_health_professionals&sa=N&oi=coopctx&resnum=0&ct=col1&cd=3 Patient Handouts on {{PAGENAME}}]
<br>
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[http://blogsearch.google.com/blogsearch?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&sa=N&tab=wb Blogs on {{PAGENAME}}]
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[http://news.google.com/news?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&sa=N&tab=wn {{PAGENAME}} in the News]
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[http://finance.google.com/finance?ie=UTF-8&oe=utf-8&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&qt_s=Search&sa=N&tab=te {{PAGENAME}} in the Marketplace]
<br>
<br>
</font size><small>[[{{PAGENAME}}#Dosing and Administration|Return to top]]</small><font size="4">
<br>
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==International Resources==
{{Antiarrhythmic agents}}
[http://www.google.com/search?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+en+espanol&ie=utf-8&oe=utf-8&aq=t&rls=org.mozilla:en-US:official&client=firefox-a {{PAGENAME}} en Español]
<br>
<br>
</font size><small>[[{{PAGENAME}}#Dosing and Administration|Return to top]]</small><font size="4">
<br>
<br>
</font size>
----
{{FDA}}


[[Category:Drugs]]
[[Category:Antiarrhythmic agents]]
[[Category:Cardiovascular Drugs]]
[[Category:Drug]]

Latest revision as of 22:14, 23 July 2014

Encainide
Clinical data
Trade namesEnkaid
AHFS/Drugs.comMicromedex Detailed Consumer Information
MedlinePlusa605040
ATC code
Legal status
Legal status
  • Withdrawn
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC22H28N2O2
Molar mass352.47 g/mol
3D model (JSmol)
  (verify)

WikiDoc Resources for Encainide

Articles

Most recent articles on Encainide

Most cited articles on Encainide

Review articles on Encainide

Articles on Encainide in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Encainide

Images of Encainide

Photos of Encainide

Podcasts & MP3s on Encainide

Videos on Encainide

Evidence Based Medicine

Cochrane Collaboration on Encainide

Bandolier on Encainide

TRIP on Encainide

Clinical Trials

Ongoing Trials on Encainide at Clinical Trials.gov

Trial results on Encainide

Clinical Trials on Encainide at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Encainide

NICE Guidance on Encainide

NHS PRODIGY Guidance

FDA on Encainide

CDC on Encainide

Books

Books on Encainide

News

Encainide in the news

Be alerted to news on Encainide

News trends on Encainide

Commentary

Blogs on Encainide

Definitions

Definitions of Encainide

Patient Resources / Community

Patient resources on Encainide

Discussion groups on Encainide

Patient Handouts on Encainide

Directions to Hospitals Treating Encainide

Risk calculators and risk factors for Encainide

Healthcare Provider Resources

Symptoms of Encainide

Causes & Risk Factors for Encainide

Diagnostic studies for Encainide

Treatment of Encainide

Continuing Medical Education (CME)

CME Programs on Encainide

International

Encainide en Espanol

Encainide en Francais

Business

Encainide in the Marketplace

Patents on Encainide

Experimental / Informatics

List of terms related to Encainide

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Encainide (trade name Enkaid) is a class Ic antiarrhythmic agent. It is no longer used because of its frequent proarrhythmic side effects.[1]

References

  1. ↑ PMID 1900101 (PMID 1900101)
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Template:Antiarrhythmic agents

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