EPC1: Difference between revisions

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{{Infobox_gene}}
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'''Enhancer of polycomb homolog 1''' is a [[protein]] that in humans is encoded by the ''EPC1'' [[gene]].<ref name="pmid10976108">{{cite journal | vauthors = Shimono Y, Murakami H, Hasegawa Y, Takahashi M | title = RET finger protein is a transcriptional repressor and interacts with enhancer of polycomb that has dual transcriptional functions | journal = J Biol Chem | volume = 275 | issue = 50 | pages = 39411–9 |date=Jan 2001 | pmid = 10976108 | pmc =  | doi = 10.1074/jbc.M006585200 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: EPC1 enhancer of polycomb homolog 1 (Drosophila)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80314| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Enhancer of polycomb homolog 1 (Drosophila)
| HGNCid = 19876
| Symbol = EPC1
| AltSymbols =; DKFZp781P2312; Epl1
| OMIM = 
| ECnumber = 
| Homologene = 32627
| MGIid = 1278322
| Function = {{GNF_GO|id=GO:0016563 |text = transcription activator activity}} {{GNF_GO|id=GO:0016564 |text = transcription repressor activity}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0001558 |text = regulation of cell growth}} {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0016568 |text = chromatin modification}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 80314
    | Hs_Ensembl = ENSG00000120616
    | Hs_RefseqProtein = NP_079485
    | Hs_RefseqmRNA = NM_025209
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 10
    | Hs_GenLoc_start = 32596694
    | Hs_GenLoc_end = 32707685
    | Hs_Uniprot = Q9H2F5
    | Mm_EntrezGene = 13831
    | Mm_Ensembl = ENSMUSG00000024240
    | Mm_RefseqmRNA = NM_007935
    | Mm_RefseqProtein = NP_031961
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 18
    | Mm_GenLoc_start = 6436758
    | Mm_GenLoc_end = 6490855
    | Mm_Uniprot = Q3UEV1
  }}
}}
'''Enhancer of polycomb homolog 1 (Drosophila)''', also known as '''EPC1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: EPC1 enhancer of polycomb homolog 1 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80314| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Doyon Y, Côté J |title=The highly conserved and multifunctional NuA4 HAT complex. |journal=Curr. Opin. Genet. Dev. |volume=14 |issue= 2 |pages= 147-54 |year= 2004 |pmid= 15196461 |doi= 10.1016/j.gde.2004.02.009 }}
*{{cite journal  | vauthors=Doyon Y, Côté J |title=The highly conserved and multifunctional NuA4 HAT complex |journal=Curr. Opin. Genet. Dev. |volume=14 |issue= 2 |pages= 147–54 |year= 2004 |pmid= 15196461 |doi= 10.1016/j.gde.2004.02.009 }}
*{{cite journal  | author=Liedtke W, Meyer G, Faustmann PM, ''et al.'' |title=Clonal expansion and decreased occurrence of peripheral blood gamma delta T cells of the V delta 2J delta 3 lineage in multiple sclerosis patients. |journal=Int. Immunol. |volume=9 |issue= 7 |pages= 1031-41 |year= 1997 |pmid= 9237112 |doi=  }}
*{{cite journal  | vauthors=Liedtke W, Meyer G, Faustmann PM |title=Clonal expansion and decreased occurrence of peripheral blood gamma delta T cells of the V delta 2J delta 3 lineage in multiple sclerosis patients |journal=Int. Immunol. |volume=9 |issue= 7 |pages= 1031–41 |year= 1997 |pmid= 9237112 |doi=10.1093/intimm/9.7.1031 |display-authors=etal}}
*{{cite journal  | author=Wang X, Stollar BD |title=Immunoglobulin VH gene expression in human aging. |journal=Clin. Immunol. |volume=93 |issue= 2 |pages= 132-42 |year= 1999 |pmid= 10527689 |doi= 10.1006/clim.1999.4781 }}
*{{cite journal  | vauthors=Wang X, Stollar BD |title=Immunoglobulin VH gene expression in human aging |journal=Clin. Immunol. |volume=93 |issue= 2 |pages= 132–42 |year= 1999 |pmid= 10527689 |doi= 10.1006/clim.1999.4781 }}
*{{cite journal  | author=Shimono Y, Murakami H, Hasegawa Y, Takahashi M |title=RET finger protein is a transcriptional repressor and interacts with enhancer of polycomb that has dual transcriptional functions. |journal=J. Biol. Chem. |volume=275 |issue= 50 |pages= 39411-9 |year= 2001 |pmid= 10976108 |doi= 10.1074/jbc.M006585200 }}
*{{cite journal  | vauthors=Kenny TP, Semrad TJ, Malyj W, Robbins DL |title=Mutational analysis of immunoglobulin germline derived Vlambda4B light chains in rheumatoid arthritis |journal=Clin. Immunol. |volume=99 |issue= 2 |pages= 283–90 |year= 2001 |pmid= 11318600 |doi= 10.1006/clim.2001.5020 }}
*{{cite journal  | author=Kenny TP, Semrad TJ, Malyj W, Robbins DL |title=Mutational analysis of immunoglobulin germline derived Vlambda4B light chains in rheumatoid arthritis. |journal=Clin. Immunol. |volume=99 |issue= 2 |pages= 283-90 |year= 2001 |pmid= 11318600 |doi= 10.1006/clim.2001.5020 }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Cai Y, Jin J, Tomomori-Sato C |title=Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex |journal=J. Biol. Chem. |volume=278 |issue= 44 |pages= 42733–6 |year= 2003 |pmid= 12963728 |doi= 10.1074/jbc.C300389200 |display-authors=etal}}
*{{cite journal  | author=Cai Y, Jin J, Tomomori-Sato C, ''et al.'' |title=Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. |journal=J. Biol. Chem. |volume=278 |issue= 44 |pages= 42733-6 |year= 2003 |pmid= 12963728 |doi= 10.1074/jbc.C300389200 }}
*{{cite journal  | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | vauthors=Doyon Y, Selleck W, Lane WS |title=Structural and Functional Conservation of the NuA4 Histone Acetyltransferase Complex from Yeast to Humans |journal=Mol. Cell. Biol. |volume=24 |issue= 5 |pages= 1884–96 |year= 2004 |pmid= 14966270 |doi=10.1128/MCB.24.5.1884-1896.2004  | pmc=350560 |display-authors=etal}}
*{{cite journal  | author=Doyon Y, Selleck W, Lane WS, ''et al.'' |title=Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. |journal=Mol. Cell. Biol. |volume=24 |issue= 5 |pages= 1884-96 |year= 2004 |pmid= 14966270 |doi=  }}
*{{cite journal  | vauthors=Deloukas P, Earthrowl ME, Grafham DV |title=The DNA sequence and comparative analysis of human chromosome 10 |journal=Nature |volume=429 |issue= 6990 |pages= 375–81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462 |display-authors=etal}}
*{{cite journal  | author=Deloukas P, Earthrowl ME, Grafham DV, ''et al.'' |title=The DNA sequence and comparative analysis of human chromosome 10. |journal=Nature |volume=429 |issue= 6990 |pages= 375-81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462 }}
*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | vauthors=Attwooll C, Oddi S, Cartwright P |title=A novel repressive E2F6 complex containing the polycomb group protein, EPC1, that interacts with EZH2 in a proliferation-specific manner |journal=J. Biol. Chem. |volume=280 |issue= 2 |pages= 1199–208 |year= 2005 |pmid= 15536069 |doi= 10.1074/jbc.M412509200 |display-authors=etal}}
*{{cite journal  | author=Attwooll C, Oddi S, Cartwright P, ''et al.'' |title=A novel repressive E2F6 complex containing the polycomb group protein, EPC1, that interacts with EZH2 in a proliferation-specific manner. |journal=J. Biol. Chem. |volume=280 |issue= 2 |pages= 1199-208 |year= 2005 |pmid= 15536069 |doi= 10.1074/jbc.M412509200 }}
*{{cite journal  | vauthors=Cai Y, Jin J, Florens L |title=The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes |journal=J. Biol. Chem. |volume=280 |issue= 14 |pages= 13665–70 |year= 2005 |pmid= 15647280 |doi= 10.1074/jbc.M500001200 |display-authors=etal}}
*{{cite journal  | author=Cai Y, Jin J, Florens L, ''et al.'' |title=The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. |journal=J. Biol. Chem. |volume=280 |issue= 14 |pages= 13665-70 |year= 2005 |pmid= 15647280 |doi= 10.1074/jbc.M500001200 }}
*{{cite journal  | vauthors=Beausoleil SA, Villén J, Gerber SA |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 |display-authors=etal}}
*{{cite journal  | author=Beausoleil SA, Villén J, Gerber SA, ''et al.'' |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285-92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 }}
*{{cite journal  | vauthors=Kee HJ, Kim JR, Nam KI |title=Enhancer of polycomb1, a novel homeodomain only protein-binding partner, induces skeletal muscle differentiation |journal=J. Biol. Chem. |volume=282 |issue= 10 |pages= 7700–9 |year= 2007 |pmid= 17192267 |doi= 10.1074/jbc.M611198200 |display-authors=etal}}
*{{cite journal  | author=Kee HJ, Kim JR, Nam KI, ''et al.'' |title=Enhancer of polycomb1, a novel homeodomain only protein-binding partner, induces skeletal muscle differentiation. |journal=J. Biol. Chem. |volume=282 |issue= 10 |pages= 7700-9 |year= 2007 |pmid= 17192267 |doi= 10.1074/jbc.M611198200 }}
}}
}}
{{refend}}
{{refend}}


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Latest revision as of 16:01, 13 February 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Enhancer of polycomb homolog 1 is a protein that in humans is encoded by the EPC1 gene.[1][2]


References

  1. Shimono Y, Murakami H, Hasegawa Y, Takahashi M (Jan 2001). "RET finger protein is a transcriptional repressor and interacts with enhancer of polycomb that has dual transcriptional functions". J Biol Chem. 275 (50): 39411–9. doi:10.1074/jbc.M006585200. PMID 10976108.
  2. "Entrez Gene: EPC1 enhancer of polycomb homolog 1 (Drosophila)".

Further reading