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{{Infobox_gene}}
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'''Epithelial membrane protein 1''' is a [[protein]] that in humans is encoded by the ''EMP1'' [[gene]].<ref name="pmid8996089">{{cite journal | vauthors = Ben-Porath I, Benvenisty N | title = Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins | journal = Gene | volume = 183 | issue = 1–2 | pages = 69–75 |date=Feb 1997 | pmid = 8996089 | pmc =  | doi =10.1016/S0378-1119(96)00475-1 }}</ref><ref name="pmid9126480">{{cite journal | vauthors = Chen Y, Medvedev A, Ruzanov P, Marvin KW, Jetten AM | title = cDNA cloning, genomic structure, and chromosome mapping of the human epithelial membrane protein CL-20 gene (EMP1), a member of the PMP22 family | journal = Genomics | volume = 41 | issue = 1 | pages = 40–8 |date=May 1997 | pmid = 9126480 | pmc =  | doi = 10.1006/geno.1997.4524 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: EMP1 epithelial membrane protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2012| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Epithelial membrane protein 1
| HGNCid = 3333
| Symbol = EMP1
| AltSymbols =; CL-20; EMP-1; TMP
| OMIM = 602333
| ECnumber =
| Homologene = 1088
| MGIid = 107941
  | GeneAtlas_image1 = PBB_GE_EMP1_201324_at_tn.png
| GeneAtlas_image2 = PBB_GE_EMP1_201325_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_EMP1_213895_at_tn.png
| Function =
  | Component = {{GNF_GO|id=GO:0005624 |text = membrane fraction}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0008219 |text = cell death}} {{GNF_GO|id=GO:0008283 |text = cell proliferation}} {{GNF_GO|id=GO:0008544 |text = epidermis development}} {{GNF_GO|id=GO:0016049 |text = cell growth}}
  | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 2012
    | Hs_Ensembl = ENSG00000134531
    | Hs_RefseqProtein = NP_001414
    | Hs_RefseqmRNA = NM_001423
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 12
    | Hs_GenLoc_start = 13240900
    | Hs_GenLoc_end = 13260971
    | Hs_Uniprot = P54849
    | Mm_EntrezGene = 13730
    | Mm_Ensembl = ENSMUSG00000030208
    | Mm_RefseqmRNA = NM_010128
    | Mm_RefseqProtein = NP_034258
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 6
    | Mm_GenLoc_start = 135328624
    | Mm_GenLoc_end = 135348868
    | Mm_Uniprot = Q05BR0
  }}
}}
'''Epithelial membrane protein 1''', also known as '''EMP1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: EMP1 epithelial membrane protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2012| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Jain A, Tindell CA, Laux I, ''et al.'' |title=Epithelial membrane protein-1 is a biomarker of gefitinib resistance. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 33 |pages= 11858-63 |year= 2005 |pmid= 16087880 |doi= 10.1073/pnas.0502113102 }}
*{{cite journal  | vauthors=Jain A, Tindell CA, Laux I |title=Epithelial membrane protein-1 is a biomarker of gefitinib resistance |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 33 |pages= 11858–63 |year= 2005 |pmid= 16087880 |doi= 10.1073/pnas.0502113102 | pmc=1187965 |display-authors=etal}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
*{{cite journal  | author=Wang HT, Kong JP, Ding F, ''et al.'' |title=Analysis of gene expression profile induced by EMP-1 in esophageal cancer cells using cDNA Microarray. |journal=World J. Gastroenterol. |volume=9 |issue= 3 |pages= 392-8 |year= 2003 |pmid= 12632483 |doi=  }}
*{{cite journal  | vauthors=Wang HT, Kong JP, Ding F |title=Analysis of gene expression profile induced by EMP-1 in esophageal cancer cells using cDNA Microarray |journal=World J. Gastroenterol. |volume=9 |issue= 3 |pages= 392–8 |year= 2003 |pmid= 12632483 |doi=  |display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Wang HT, Liu ZH, Wang XQ, Wu M |title=[Effect of EMP-1 gene on human esophageal cancer cell line] |journal=Ai Zheng |volume=21 |issue= 3 |pages= 229-32 |year= 2003 |pmid= 12451984 |doi=  }}
*{{cite journal  | vauthors=Wang HT, Liu ZH, Wang XQ, Wu M |title=[Effect of EMP-1 gene on human esophageal cancer cell line] |journal=Ai Zheng |volume=21 |issue= 3 |pages= 229–32 |year= 2003 |pmid= 12451984 |doi=  }}
*{{cite journal  | author=Liehr T, Kuhlenbäumer G, Wulf P, ''et al.'' |title=Regional localization of the human epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, EMP3) to 12p12.3, 16p13.2, and 19q13.3. |journal=Genomics |volume=58 |issue= 1 |pages= 106-8 |year= 1999 |pmid= 10331954 |doi= 10.1006/geno.1999.5803 }}
*{{cite journal  | vauthors=Liehr T, Kuhlenbäumer G, Wulf P |title=Regional localization of the human epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, EMP3) to 12p12.3, 16p13.2, and 19q13.3 |journal=Genomics |volume=58 |issue= 1 |pages= 106–8 |year= 1999 |pmid= 10331954 |doi= 10.1006/geno.1999.5803 |display-authors=etal}}
*{{cite journal  | author=Chen Y, Medvedev A, Ruzanov P, ''et al.'' |title=cDNA cloning, genomic structure, and chromosome mapping of the human epithelial membrane protein CL-20 gene (EMP1), a member of the PMP22 family. |journal=Genomics |volume=41 |issue= 1 |pages= 40-8 |year= 1997 |pmid= 9126480 |doi= 10.1006/geno.1997.4524 }}
*{{cite journal  | vauthors=Schiemann S, Rückels M, Engelholm LH |title=Differential gene expression in human mammary carcinoma cells: identification of a new member of a receptor family |journal=Anticancer Res. |volume=17 |issue= 1A |pages= 13–20 |year= 1997 |pmid= 9066625 |doi=  |display-authors=etal}}
*{{cite journal  | author=Schiemann S, Rückels M, Engelholm LH, ''et al.'' |title=Differential gene expression in human mammary carcinoma cells: identification of a new member of a receptor family. |journal=Anticancer Res. |volume=17 |issue= 1A |pages= 13-20 |year= 1997 |pmid= 9066625 |doi=  }}
*{{cite journal  | vauthors=Lobsiger CS, Magyar JP, Taylor V |title=Identification and characterization of a cDNA and the structural gene encoding the mouse epithelial membrane protein-1 |journal=Genomics |volume=36 |issue= 3 |pages= 379–87 |year= 1997 |pmid= 8884260 |doi=10.1006/geno.1996.0482 |display-authors=etal}}
*{{cite journal  | author=Ben-Porath I, Benvenisty N |title=Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins. |journal=Gene |volume=183 |issue= 1-2 |pages= 69-75 |year= 1997 |pmid= 8996089 |doi=  }}
*{{cite journal  | vauthors=Ruegg CL, Wu HY, Fagnoni FF |title=B4B, a novel growth-arrest gene, is expressed by a subset of progenitor/pre-B lymphocytes negative for cytoplasmic mu-chain |journal=J. Immunol. |volume=157 |issue= 1 |pages= 72–80 |year= 1996 |pmid= 8683158 |doi=  |display-authors=etal}}
*{{cite journal  | author=Lobsiger CS, Magyar JP, Taylor V, ''et al.'' |title=Identification and characterization of a cDNA and the structural gene encoding the mouse epithelial membrane protein-1. |journal=Genomics |volume=36 |issue= 3 |pages= 379-87 |year= 1997 |pmid= 8884260 |doi=  }}
*{{cite journal  | vauthors=Marvin KW, Fujimoto W, Jetten AM |title=Identification and characterization of a novel squamous cell-associated gene related to PMP22 |journal=J. Biol. Chem. |volume=270 |issue= 48 |pages= 28910–6 |year= 1996 |pmid= 7499420 |doi=10.1074/jbc.270.48.28910 }}
*{{cite journal  | author=Ruegg CL, Wu HY, Fagnoni FF, ''et al.'' |title=B4B, a novel growth-arrest gene, is expressed by a subset of progenitor/pre-B lymphocytes negative for cytoplasmic mu-chain. |journal=J. Immunol. |volume=157 |issue= 1 |pages= 72-80 |year= 1996 |pmid= 8683158 |doi=  }}
*{{cite journal  | author=Marvin KW, Fujimoto W, Jetten AM |title=Identification and characterization of a novel squamous cell-associated gene related to PMP22. |journal=J. Biol. Chem. |volume=270 |issue= 48 |pages= 28910-6 |year= 1996 |pmid= 7499420 |doi=  }}
}}
}}
{{refend}}
{{refend}}


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Latest revision as of 16:08, 13 February 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Epithelial membrane protein 1 is a protein that in humans is encoded by the EMP1 gene.[1][2][3]


References

  1. ↑ Ben-Porath I, Benvenisty N (Feb 1997). "Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins". Gene. 183 (1–2): 69–75. doi:10.1016/S0378-1119(96)00475-1. PMID 8996089.
  2. ↑ Chen Y, Medvedev A, Ruzanov P, Marvin KW, Jetten AM (May 1997). "cDNA cloning, genomic structure, and chromosome mapping of the human epithelial membrane protein CL-20 gene (EMP1), a member of the PMP22 family". Genomics. 41 (1): 40–8. doi:10.1006/geno.1997.4524. PMID 9126480.
  3. ↑ "Entrez Gene: EMP1 epithelial membrane protein 1".

Further reading



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