DVT complete diagnostic approach resident survival guide

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Complete Diagnostic Approach

A complete diagnostic approach should be carried out after a focused initial rapid evaluation is conducted and following initiation of any urgent intervention.[1]

 
 
 
 
 
 
Characterize the symptoms in the involved extremity:

❑ Swelling
❑ Pain
❑ Erythema

❑ Warmth
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Identify possible precipitating factors:
❑ Recent surgery
❑ Hospitalization
Trauma
Pregnancy
Postpartum
Heart failure
❑ Immobility
❑ Obesity
Malignancy
Stroke
Oral contraceptive or hormone replacement therapy


Obtain a detailed history:
❑ Previous episode of VTE

❑ Age
❑ Location

❑ Past medical history:

Collagen vascular disease
Myeloproliferative disease
Nephrotic syndrome
Atherosclerosis

❑ Abortion at second or third trimester of pregancy (suggestive of an inherited thrombophilia or APS)
❑ Drugs that may induce APS

Hydralazine
Phenothiazine
Procainamide
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Examine the patient:

Vital signs


 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Consider alternative diagnoses:

Muscle strain or muscle tear
Immobilization that led to leg swelling
Lymphedema
Lymphangitis
Venous valvular insufficiency
Baker's cyst
Cellulitis
Superficial thrombophlebitis

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Order tests:

CBC-D
PT and aPTTCreatinine (to rule out nephrotic syndrome)

Liver function test
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Is the suspected DVT a first or a recurrent episode?
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
First suspected episode
 
Suspected recurrent episode
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Low pretest probability
(Click here for the diagnostic approach)
 
Moderate pretest probability
(Click here for the diagnostic approach)
 
High pretest probability
(Click here for the diagnostic approach)
 
 
 

Assessment of the Pre-Test Probability of DVT

Calculation of Wells Score for DVT

Variables Score[2]
Active cancer with either palliative therapy or treatment that is either ongoing or within the prior 6 months 1
Patient was recently bedridden for at least 3 days
OR Major surgery in the prior 12 weeks necessitating general or regional anesthesia
1
Recent plaster immobilization, paresis or paralysis of the lower extremities 1
Tenderness that is localized is the distribution of the deep veins 1
Leg is entirely swollen 1
Calf is swollen for 3 cm or move compared to the other calf 1
Pitting edema in the symptomatic leg 1
Presence of collateral superficial veins 1
Previous DVT 1
There is an alternative diagnosis as likely as DVT -2

Interpretation of Wells Score for DVT

Score Pretest probability[2][3]
≥3 High
1 or 2 Moderate
0 or less Low

Modified Well Score

[4] Normal 0 false false false EN-US X-NONE X-NONE

  1. Bates SM, Jaeschke R, Stevens SM, Goodacre S, Wells PS, Stevenson MD; et al. (2012). "Diagnosis of DVT: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines". Chest. 141 (2 Suppl): e351S–418S. doi:10.1378/chest.11-2299. PMC 3278048. PMID 22315267.
  2. 2.0 2.1 Wells PS, Owen C, Doucette S, Fergusson D, Tran H (2006). "Does this patient have deep vein thrombosis?". JAMA. 295 (2): 199–207. doi:10.1001/jama.295.2.199. PMID 16403932. Review in: Evid Based Med. 2006 Aug;11(4):119 Review in: ACP J Club. 2006 Jul-Aug;145(1):24
  3. Wells PS, Anderson DR, Bormanis J, Guy F, Mitchell M, Gray L; et al. (1997). "Value of assessment of pretest probability of deep-vein thrombosis in clinical management". Lancet. 350 (9094): 1795–8. doi:10.1016/S0140-6736(97)08140-3. PMID 9428249.
  4. Wells PS, Anderson DR, Rodger M, Forgie M, Kearon C, Dreyer J; et al. (2003). "Evaluation of D-dimer in the diagnosis of suspected deep-vein thrombosis". N Engl J Med. 349 (13): 1227–35. doi:10.1056/NEJMoa023153. PMID 14507948. Review in: ACP J Club. 2004 May-Jun;140(3):67