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'''Cumulative incidence''' is a measure of frequency, as in [[epidemiology]], where it is a measure of disease frequency during a period of time.
==Overview==
'''Cumulative incidence''' (sometimes referred to as '''incidence proportion''') is a measure of disease frequency which counts the proportion of a candidate population that becomes diseased/develops disease over a specified period of time. Cumulative incidence measures occurrence of '''new cases'' of disease. It involves the transition from one state to another, such as non-disease to diseased state (incidence of disease) or diseased to non-diseased (incidence of cure).


Cumulative incidence is the incidence calculated using a period of time during which all of the individuals in the population are considered to be at risk for the outcome.
Specific forms of cumulative incidence include:
It is sometimes referred to as the incidence proportion or the attack rate.
* Crude mortality rate: number of deaths due to any cause/100,000 population during a specified time period
* Infant mortality rate: number of infant deaths due to any cause/1,000 population during a specified time period
* Morbidity rate: number of illnesses due to any cause/1,000 population during a specified time period
* Live birth rate: number of live births/1,000 population or childbearing women during a specified time period
* Case fatality rate: number of deaths due to disease X/number of people with disease X during a specified time period
* Attack rate: number of new cases of disease/number population at risk at beginning of time period during specified time period


Cumulative incidence is calculated by the number of new cases during a period divided by the number of people at risk in the population at the beginning of the study.
==Calculating Cumulative Incidence==
It may also be calculated by the [[incidence rate]] multiplied by duration.


It may also be calculated by the [[incidence rate]] multiplied by duration.
''''Basic equation:'''' Cumulative Incidence = # new (incident) cases/total population at risk
''''Applied:'''' CI = IR<sub>i</sub> * t<sub>i</sub> (where IR<sub>i</sub> is the incidence rate, t<sub>i</sub> is the specified time period)


<math>CI(t)=1-e^{-IR(t) * D}\,</math>
==References==
{{reflist|2}}


{{SIB}}


[[Category:Epidemiology]]
[[Category:Epidemiology]]

Revision as of 15:15, 21 December 2011

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Overview

'Cumulative incidence (sometimes referred to as incidence proportion) is a measure of disease frequency which counts the proportion of a candidate population that becomes diseased/develops disease over a specified period of time. Cumulative incidence measures occurrence of new cases of disease. It involves the transition from one state to another, such as non-disease to diseased state (incidence of disease) or diseased to non-diseased (incidence of cure).

Specific forms of cumulative incidence include:

  • Crude mortality rate: number of deaths due to any cause/100,000 population during a specified time period
  • Infant mortality rate: number of infant deaths due to any cause/1,000 population during a specified time period
  • Morbidity rate: number of illnesses due to any cause/1,000 population during a specified time period
  • Live birth rate: number of live births/1,000 population or childbearing women during a specified time period
  • Case fatality rate: number of deaths due to disease X/number of people with disease X during a specified time period
  • Attack rate: number of new cases of disease/number population at risk at beginning of time period during specified time period

Calculating Cumulative Incidence

It may also be calculated by the incidence rate multiplied by duration.

'Basic equation:' Cumulative Incidence = # new (incident) cases/total population at risk 'Applied:' CI = IRi * ti (where IRi is the incidence rate, ti is the specified time period)

References


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