Cryptogenic organizing pneumonia pathophysiology: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
*The organizing pneumonia pathogenesis model is very similar to the that of cutaneous wound healing. | |||
*Following an insult, a recovery phase characterized by the organisation of inflammatory exudates with resulting intra-alveolar fibrosis ensues. | |||
*Although the intra-alveolar fibrosis resembles that present in usual interstitial pneumonia (UIP), it is however not associated with irreversible fibrosis. In contrast, cryptogenic organizing pneumonia is characterized by it's favorable response to corticosteroid therapy.<ref name="pmid16880372">{{cite journal| author=Cordier JF| title=Cryptogenic organising pneumonia. | journal=Eur Respir J | year= 2006 | volume= 28 | issue= 2 | pages= 422-46 | pmid=16880372 | doi=10.1183/09031936.06.00013505 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16880372 }} </ref> | |||
==References== | ==References== | ||
Revision as of 19:15, 8 March 2016
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Cryptogenic Organizing Pneumonia Microchapters |
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Differentiating Cryptogenic organizing pneumonia from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Serge Korjian M.D.
Overview
Pathophysiology
- The organizing pneumonia pathogenesis model is very similar to the that of cutaneous wound healing.
- Following an insult, a recovery phase characterized by the organisation of inflammatory exudates with resulting intra-alveolar fibrosis ensues.
- Although the intra-alveolar fibrosis resembles that present in usual interstitial pneumonia (UIP), it is however not associated with irreversible fibrosis. In contrast, cryptogenic organizing pneumonia is characterized by it's favorable response to corticosteroid therapy.[1]
References
- ↑ Cordier JF (2006). "Cryptogenic organising pneumonia". Eur Respir J. 28 (2): 422–46. doi:10.1183/09031936.06.00013505. PMID 16880372.