Cryptogenic organizing pneumonia laboratory findings: Difference between revisions

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==Laboratory Findings==
==Laboratory Findings==
*There are no specific laboratory findings associated with [[cryptogenic organizing pneumonia]].
*There are no specific laboratory findings associated with [[cryptogenic organizing pneumonia]].
*If there is the history of [[cryptogenic organizing pneumonia]] then following laboratory test is done:
*If there is the history of [[cryptogenic organizing pneumonia]] and patients present with a cough, fever, and dyspnea then following laboratory test is to be done:
 
**Complete blood count with differentials- leukocytosis is found in most of the patients.
In patients with typical clinical and radiographic features, a transbronchial biopsy that shows the pathologic pattern of organizing pneumonia and lacks features of an alternative diagnosis is adequate to make a tentative diagnosis and start therapy. On surgical lung biopsy, the histopathologic pattern is organizing pneumonia with preserved lung architecture; this pattern is not exclusive to BOOP and must be interpreted in the clinical context. Most patients recover with corticosteroid therapy. A standardized approach to dosing starting at 0.75 mg/kg and weaning over 24 weeks has been shown to reduce total corticosteroid exposure without affecting outcome.
**Blood urea nitrogen
**Creatinine
**Urinalysis
**ESR
**C-reactive protein
*To find the etiology of cryptogenic organizing pneumonia following tests are done:
**Test for antibodies to rule out connective tissue disorder.
**Antinuclear antibody
**Rheumatoid factor
**Anti-topoisomerase [anti-Scl70]
**Anti-centromere antibody
**Anti-double-stranded DNA
**Anti-JO1


==References==
==References==

Revision as of 16:44, 28 February 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]

Overview

Laboratory Findings

  • There are no specific laboratory findings associated with cryptogenic organizing pneumonia.
  • If there is the history of cryptogenic organizing pneumonia and patients present with a cough, fever, and dyspnea then following laboratory test is to be done:
    • Complete blood count with differentials- leukocytosis is found in most of the patients.
    • Blood urea nitrogen
    • Creatinine
    • Urinalysis
    • ESR
    • C-reactive protein
  • To find the etiology of cryptogenic organizing pneumonia following tests are done:
    • Test for antibodies to rule out connective tissue disorder.
    • Antinuclear antibody
    • Rheumatoid factor
    • Anti-topoisomerase [anti-Scl70]
    • Anti-centromere antibody
    • Anti-double-stranded DNA
    • Anti-JO1

References

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