Craniopharyngioma differential diagnosis: Difference between revisions

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*'''S''': [[Sarcoid]], sellar tumour ([[pituitary]] adenoma)
*'''S''': [[Sarcoid]], sellar tumour ([[pituitary]] adenoma)
*'''A''': [[Aneurysm]]
*'''A''': [[Aneurysm]]
*'''T''': [[Teratoma]] or [[tuberculosis]] (and other [[granulomatous diseases]])
*'''T''': [[Teratoma]] or [[tuberculosis]] (and other granulomatous diseases)
*'''C''': Cleft cyst ([[Rathke]]), [[chordoma]]
*'''C''': Cleft cyst (Rathke), [[chordoma]]
*'''H''': Hypothalamic glioma, [[hamartoma]] of tuber cinereum, [[histiocytosis]]
*'''H''': Hypothalamic glioma, [[hamartoma]] of tuber cinereum, [[histiocytosis]]
*'''M''': [[Meningioma]], [[metastasis]]
*'''M''': [[Meningioma]], [[metastasis]]
Line 17: Line 17:


General ''imaging differential'' considerations include:
General ''imaging differential'' considerations include:
*'''[[Rathke cleft cyst]]'''
*'''Rathke cleft cyst'''
**No solid or enhancing component
**No solid or enhancing component
**Calcification is rare
**Calcification is rare
**Unilocular
**Unilocular
**Majority are completely or mostly intrasellar
**Majority are completely or mostly intrasellar
*'''[[Pituitary macroadenoma]]''' (with cystic degeneration or [[necrosis]])
*'''Pituitary macroadenoma''' (with cystic degeneration or [[necrosis]])
**Can look very similar
**Can look very similar
**Usually has [[intrasellar]] epicentre with pituitary fossa enlargement rather than [[suprasellar]] epicentre
**Usually has intrasellar epicentre with pituitary fossa enlargement rather than [[suprasellar]] epicentre
**Despite occasional presence of T1 bright cystic regions, calcification in these cases is often absent (whereas most adamantinomatous craniopharyngiomas are calcified)
**Despite occasional presence of T1 bright cystic regions, calcification in these cases is often absent (whereas most adamantinomatous craniopharyngiomas are calcified)
*'''Intracranial [[teratoma]]'''
*'''Intracranial [[teratoma]]'''

Revision as of 18:45, 24 August 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Craniopharyngioma must be differentiated from other pituitary masses such as sarcoid, pituitary adenoma, aneurysm, teratoma, tuberculosis, rathke cleft cyst, chordoma, hypothalamic glioma, hamartoma of tuber cinereum, histiocytosis, meningioma and optic nerve glioma.

Differentiating Craniopharyngioma from other Diseases

Craniopharyngioma is a mass in the pituitary region. A simple and popular mnemonic to remember the common pituitary masses that can be confused with craniopharyngioma is SATCHMO.[1]

General imaging differential considerations include:

  • Rathke cleft cyst
    • No solid or enhancing component
    • Calcification is rare
    • Unilocular
    • Majority are completely or mostly intrasellar
  • Pituitary macroadenoma (with cystic degeneration or necrosis)
    • Can look very similar
    • Usually has intrasellar epicentre with pituitary fossa enlargement rather than suprasellar epicentre
    • Despite occasional presence of T1 bright cystic regions, calcification in these cases is often absent (whereas most adamantinomatous craniopharyngiomas are calcified)
  • Intracranial teratoma
    • Presence of fat is helpful, but requires fat saturated sequences or CT to confirm

References

  1. Differtials of Craniopharyngioma. Dr Henry Knipe and Dr Daryl Bergen et al. Radiopaedia. http://radiopaedia.org/articles/pituitary-region-masses-mnemonic-1


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