Craniopharyngioma: Difference between revisions

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==Overview==
{{Craniopharyngioma}}


'''Craniopharyngioma''' is a type of [[tumor]] that comprises 9% of all [[pediatric]] [[brain tumor]]s. They usually occur in children between 5 and 10 years of age.<ref name="pmid17703145">{{cite journal |author=Hamid R, Sarkar S, Hossain MA, Mazumder U, Akanda NI, Parvin R |title=Clinical picture of craniopharyngioma in childhood |journal=Mymensingh medical journal : MMJ |volume=16 |issue=2 |pages=123-6 |year=2007 |pmid=17703145 |doi=}}</ref>
{{CMG}}


It has a point [[prevalence]] of approximately 2/100,000.<ref name="pmid17425791">{{cite journal |author=Garnett MR, Puget S, Grill J, Sainte-Rose C |title=Craniopharyngioma |journal=Orphanet journal of rare diseases |volume=2 |issue= |pages=18 |year=2007 |pmid=17425791 |doi=10.1186/1750-1172-2-18}}</ref>
==[[Craniopharyngioma overview|Overview]]==


They are also known as [[Rathke pouch]] tumors, hypophyseal duct tumors, or adamantinomas.
==[[Craniopharyngioma historical perspective|Historical perspective]]==


==Presentation==
==[[Craniopharyngioma pathophysiology|Pathophysiology]]==
They are very slow growing tumors. They arise from the cells along the [[pituitary stalk]]. They are classified as [[benign]].<ref name="pmid17630614">{{cite journal |author=Garrè ML, Cama A |title=Craniopharyngioma: modern concepts in pathogenesis and treatment |journal=Curr. Opin. Pediatr. |volume=19 |issue=4 |pages=471-9 |year=2007 |pmid=17630614 |doi=10.1097/MOP.0b013e3282495a22}}</ref>


Craniopharyngioma is a rare, usually [[suprasellar]]<ref name="pmid17592268">{{cite journal |author=Rodriguez FJ, Scheithauer BW, Tsunoda S, Kovacs K, Vidal S, Piepgras DG |title=The spectrum of malignancy in craniopharyngioma |journal=Am. J. Surg. Pathol. |volume=31 |issue=7 |pages=1020-8 |year=2007 |pmid=17592268 |doi=10.1097/PAS.0b013e31802d8a96}}</ref> neoplasm, which may be [[cystic]], that develops from the nests of epithelium derived from [[Rathke's pouch]].
==[[Craniopharyngioma epidemiology and demographics|Epidemiology & demographics]]==


==Histology==
==[[Craniopharyngioma risk factors|Risk factors]]==
The [[histologic]] pattern consists of nesting of [[squamous]] [[epithelium]] bordered by radially arranged cells. It is frequently accompanied by calcium deposition and have a microscopic papillary architecture.


==Possible symptoms==
==[[Craniopharyngioma screening|Screening]]==
* [[Anorexia (symptom)|Anorexia]]
* [[Balance disorder]]
* [[Dry skin]]
* [[Fatigue (physical)|Fatigue]]
* [[Fever]]
* [[Headache]] (obstructive [[hydrocephalus]])
* [[Lethargy]]
* [[Myxedema]]
* [[Nausea]]
* [[Short stature]]
* [[Polydipsia]]
* [[Polyuria]] ([[diabetes insipidus]])
* [[Vision loss]] ([[bitemporal hemianopsia]])
* [[Vomiting]]
* [[Weight gain]]
* [[amenorrhea]]


==Diagnostic Findings==
==[[Craniopharyngioma causes|Causes]]==


===MRI===
==[[Craniopharyngioma differential diagnosis|Differentiating craniopharyngioma from other diseases]]==


([http://www.radswiki.net Images courtesy of RadsWiki])
==[[Craniopharyngioma natural history|Natural History, Complications & Prognosis]]==


<gallery>
==Diagnosis==
Image:Craniopharyngioma-001.jpg|Craniopharyngioma
[[Craniopharyngioma history and symptoms|History & Symptoms]] | [[Craniopharyngioma physical examination|Physical Examination]] | [[Craniopharyngioma laboratory tests|Lab Tests]] | [[Craniopharyngioma electrocardiogram|Electrocardiogram]] | [[Craniopharyngioma chest x ray|Chest X Ray]] | [[Craniopharyngioma CT|CT]] | [[Craniopharyngioma MRI|MRI]] | [[Craniopharyngioma echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Craniopharyngioma other imaging findings|Other Imaging Findings]] | [[Craniopharyngioma other diagnostic studies|Other Diagnostic Studies]]
Image:Craniopharyngioma-002.jpg|Craniopharyngioma
Image:Craniopharyngioma-003.jpg|Craniopharyngioma
Image:Craniopharyngioma-004.jpg|Craniopharyngioma
Image:Craniopharyngioma-005.jpg|Craniopharyngioma
</gallery>


==References==
==Treatment==
{{Reflist|2}}
[[Craniopharyngioma medical therapy|Medical therapy]] | [[Craniopharyngioma surgery|Surgery]] | [[Craniopharyngioma primary prevention|Primary prevention]] | [[Craniopharyngioma secondary prevention|Secondary prevention]]


{{Nervous tissue tumors}}
{{Nervous tissue tumors}}
{{SIB}}
 
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[[Category:Disease]]
[[Category:Types of cancer]]
[[Category:Types of cancer]]
[[Category:Neurology]]
[[Category:Neurology]]
[[Category:Neurosurgery]]
[[Category:Neurosurgery]]
[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Mature chapter]]
[[Category:Mature chapter]]

Revision as of 17:36, 18 January 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

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