Craniopharyngioma: Difference between revisions

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{{DiseaseDisorder infobox |
  Name          = Craniopharyngioma |
  ICD10          = {{ICD10|D|44|4|d|37}} |
  ICD9          = {{ICD9|237.0}} |
  ICDO          = 9350/1 |
  Image          = Craniopharyngioma1.jpg |
  Caption        = Craniopharyngioma |
  OMIM          = |
  MedlinePlus    = 000345 |
  eMedicineSubj  = radio |
  eMedicineTopic = 196 |
  DiseasesDB    = 3153 |
  MeshID        = D003397 |
}}
{{Search infobox}}
{{CMG}}
__NOTOC__
__NOTOC__
{{Editor Help}}


=Overview==
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''.
{{Craniopharyngioma}}
{{CMG}}{{AE}}{{Marjan}}


'''Craniopharyngioma''' is a type of [[tumor]] that comprises 9% of all [[pediatric]] [[brain tumor]]s. They usually occur in children between 5 and 10 years of age.<ref name="pmid17703145">{{cite journal |author=Hamid R, Sarkar S, Hossain MA, Mazumder U, Akanda NI, Parvin R |title=Clinical picture of craniopharyngioma in childhood |journal=Mymensingh medical journal : MMJ |volume=16 |issue=2 |pages=123-6 |year=2007 |pmid=17703145 |doi=}}</ref>
{{SK}} Rathke pouch tumor; pituitary adamantinoma; hypophyseal duct tumor.


It has a point [[prevalence]] of approximately 2/100,000.<ref name="pmid17425791">{{cite journal |author=Garnett MR, Puget S, Grill J, Sainte-Rose C |title=Craniopharyngioma |journal=Orphanet journal of rare diseases |volume=2 |issue= |pages=18 |year=2007 |pmid=17425791 |doi=10.1186/1750-1172-2-18}}</ref>
==[[Craniopharyngioma overview|Overview]]==


They are also known as [[Rathke pouch]] tumors, hypophyseal duct tumors, or adamantinomas.
==[[Craniopharyngioma historical perspective|Historical perspective]]==


==Presentation==
==[[Craniopharyngioma classification|Classification]]==
They are very slow growing tumors. They arise from the cells along the [[pituitary stalk]]. They are classified as [[benign]].<ref name="pmid17630614">{{cite journal |author=Garrè ML, Cama A |title=Craniopharyngioma: modern concepts in pathogenesis and treatment |journal=Curr. Opin. Pediatr. |volume=19 |issue=4 |pages=471-9 |year=2007 |pmid=17630614 |doi=10.1097/MOP.0b013e3282495a22}}</ref>


Craniopharyngioma is a rare, usually [[suprasellar]]<ref name="pmid17592268">{{cite journal |author=Rodriguez FJ, Scheithauer BW, Tsunoda S, Kovacs K, Vidal S, Piepgras DG |title=The spectrum of malignancy in craniopharyngioma |journal=Am. J. Surg. Pathol. |volume=31 |issue=7 |pages=1020-8 |year=2007 |pmid=17592268 |doi=10.1097/PAS.0b013e31802d8a96}}</ref> neoplasm, which may be [[cystic]], that develops from the nests of epithelium derived from [[Rathke's pouch]].
==[[Craniopharyngioma pathophysiology|Pathophysiology]]==


==Histology==
==[[Craniopharyngioma differential diagnosis|Differentiating Craniopharyngioma from other diseases]]==
The [[histologic]] pattern consists of nesting of [[squamous]] [[epithelium]] bordered by radially arranged cells. It is frequently accompanied by calcium deposition and have a microscopic papillary architecture.


==Possible symptoms==
==[[Craniopharyngioma epidemiology and demographics|Epidemiology and demographics]]==
* [[Anorexia (symptom)|Anorexia]]
* [[Balance disorder]]
* [[Dry skin]]
* [[Fatigue (physical)|Fatigue]]
* [[Fever]]
* [[Headache]] (obstructive [[hydrocephalus]])
* [[Lethargy]]
* [[Myxedema]]
* [[Nausea]]
* [[Short stature]]
* [[Polydipsia]]
* [[Polyuria]] ([[diabetes insipidus]])
* [[Vision loss]] ([[bitemporal hemianopsia]])
* [[Vomiting]]
* [[Weight gain]]
* [[amenorrhea]]


==Diagnostic Findings==
==[[Craniopharyngioma risk factors|Risk factors]]==


===MRI===
==[[Craniopharyngioma screening|Screening]]==


([http://www.radswiki.net Images courtesy of RadsWiki])
==[[Craniopharyngioma natural history|Natural History, Complications and Prognosis]]==


<gallery>
==Diagnosis==
Image:Craniopharyngioma-001.jpg|Craniopharyngioma
[[Craniopharyngioma diagnostic study of choice|Diagnostic study of choice]]  [[Craniopharyngioma history and symptoms|History and Symptoms]] | [[Craniopharyngioma physical examination|Physical Examination]] | [[Craniopharyngioma laboratory tests|Laboratory Findings]] | [[Craniopharyngioma chest x ray|X Ray]] | [[Craniopharyngioma CT|CT]] | [[Craniopharyngioma MRI|MRI]] | [[Craniopharyngioma echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Craniopharyngioma other imaging findings|Other Imaging Findings]]
Image:Craniopharyngioma-002.jpg|Craniopharyngioma
Image:Craniopharyngioma-003.jpg|Craniopharyngioma
Image:Craniopharyngioma-004.jpg|Craniopharyngioma
Image:Craniopharyngioma-005.jpg|Craniopharyngioma
</gallery>


==References==
==Treatment==
{{Reflist|2}}
[[Craniopharyngioma medical therapy|Medical therapy]] | [[Craniopharyngioma surgery|Surgery]] | [[Craniopharyngioma cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Craniopharyngioma future or investigational therapies|Future or Investigational Therapies]]


==External links==
==Case Studies==
* [http://www.cinn.org/ibsc/braintumor/diagnoses/craniopharyngiomas.html CINN]
 
* [http://www.boston-neurosurg.org/publications/faq/craniopharyngRMS.shtml Boston Neurosurgical Foundation]
[[Craniopharyngioma case study one|Case #1]]
* [http://www.craniopharyngioma.org Craniopharyngioma Online Support Group]
* {{GPnotebook|194641925}}


{{Nervous tissue tumors}}
{{Nervous tissue tumors}}


[[Category:Types of cancer]]
[[Category:Neurology]]
[[Category:Neurosurgery]]
[[Category:Oncology]]
{{SIB}}
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Latest revision as of 14:14, 26 May 2019


For patient information click here.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Marjan Khan M.B.B.S.[2]

Synonyms and keywords: Rathke pouch tumor; pituitary adamantinoma; hypophyseal duct tumor.

Overview

Historical perspective

Classification

Pathophysiology

Differentiating Craniopharyngioma from other diseases

Epidemiology and demographics

Risk factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic study of choice History and Symptoms | Physical Examination | Laboratory Findings | X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings

Treatment

Medical therapy | Surgery | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

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