Coronavirus natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Clinically, most infections cause a mild, self-limiting disease (common cold or stomach upset), but there may be rare neurological complications. SARS is a form of viral pneumonia where infection encompasses the lower respiratory tract.

Natural History, Complications, and Prognosis

Natural History

• Coronavirus infection can have a highly variable disease course.
• The infection can range from being subclinical to being an overt clinical condition.

SARS

• SARS begins with a high fever (temperature greater than 100.4°F [> 38.0°C]).
• The fever can later be accompanied by headache, general feeling of discomfort, and diffuse body pain.
• The condition worsens with time and patients can develop diarrhea, dry cough, and dyspnea.