Constitutional delay of puberty pathophysiology

Revision as of 14:26, 20 September 2012 by Shankar Kumar (talk | contribs)
Jump to navigation Jump to search

Constitutional delay of puberty Microchapters

Home

Overview

Pathophysiology

Causes

Differentiating Constitutional delay of puberty from other Diseases

Epidemiology and Demographics

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

MRI

Other Diagnostic Studies

Treatment

Medical Therapy

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Constitutional delay of puberty pathophysiology On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Constitutional delay of puberty pathophysiology

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Constitutional delay of puberty pathophysiology

CDC on Constitutional delay of puberty pathophysiology

Constitutional delay of puberty pathophysiology in the news

Blogs on Constitutional delay of puberty pathophysiology

Directions to Hospitals Treating Constitutional delay of puberty

Risk calculators and risk factors for Constitutional delay of puberty pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Pathophysiology

Normal timing

Approximate mean ages for onset of various pubertal changes are as follows. Ages in parentheses are the approximate 3rd and 97th percentiles for attainment. For example, less than 3% of girls have not yet achieved thelarche by 13 years of age. Developmental changes during puberty in girls occur over a period of 3 – 5 years, usually between 9 and 14 years of age. They include the occurrence of secondary sex characteristics beginning with breast development, the adolescent growth spurt, the onset of menarche – which does not correspond to the end of puberty – and the acquisition of fertility, as well as profound psychological modifications.

The normal variation in the age at which adolescent changes occur is so wide that puberty cannot be considered to be pathologically delayed until the menarche has failed to occur by the age of 17 or testicular development by the age of 20.

For North American, Indo-Iranian (India, Iran) and European girls

For North American, Indo-Iranian (India, Iran) and European boys

  • Testicular enlargement 11.5y (9.5–13.5y)
  • Pubic hair 12y (10–14y)
  • Growth spurt 12.5–15y
  • Completion of growth 17.5

The sources of the data, and a fuller description of normal timing and sequence of pubertal events, as well as the hormonal changes that drive them, are provided in the principal article on puberty.

References

Template:WH Template:WS