Colorectal cancer other diagnostic studies: Difference between revisions
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{{Colon cancer}} | {{Colon cancer}} | ||
To view the other diagnostic studies of familial adenomatous polyposis (FAP), click [[Familial adenomatous polyposis other diagnostic studies|'''here''']]<br> | |||
To view the other diagnostic studies of hereditary nonpolyposis colorectal cancer (HNPCC), click [[Hereditary nonpolyposis colorectal cancer other diagnostic studies|'''here''']]<br><br> | |||
{{CMG}} {{AE}} Saarah T. Alkhairy, M.D. | |||
==Overview== | |||
A biopsy can be performed when a suspected lesion is found on [[colonoscopy]]. | |||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
===Biopsy=== | ===Biopsy=== | ||
A biopsy can be performed when a suspected lesion is found on [[colonoscopy]]. The biopsy specimen is examined for histologic changes and tissue differentiation. Well differentiated lesions have a good prognosis compared to poorly and undifferentiated lesions. | |||
Genetic changes in the cancer can also be observed, for example, changes in the KRAS or BRAF gene. Certain genetic mutations may not respond to a particular treatment. | |||
Microsatellite instability (MSI) testing may be performed to identify patients with HNPCC. | |||
==References== | ==References== |
Revision as of 13:39, 15 July 2015
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To view the other diagnostic studies of familial adenomatous polyposis (FAP), click here
To view the other diagnostic studies of hereditary nonpolyposis colorectal cancer (HNPCC), click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Saarah T. Alkhairy, M.D.
Overview
A biopsy can be performed when a suspected lesion is found on colonoscopy.
Other Diagnostic Studies
Biopsy
A biopsy can be performed when a suspected lesion is found on colonoscopy. The biopsy specimen is examined for histologic changes and tissue differentiation. Well differentiated lesions have a good prognosis compared to poorly and undifferentiated lesions.
Genetic changes in the cancer can also be observed, for example, changes in the KRAS or BRAF gene. Certain genetic mutations may not respond to a particular treatment.
Microsatellite instability (MSI) testing may be performed to identify patients with HNPCC.