Cluster headache causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sabeeh Islam, MBBS[2]

Overview

Cluster headaches are generally associated with underlying neurologic conditions and structural abnormalities of brain and the pituitary gland. Common causes include; Chronic paroxysmal hemicrania (CPH), Subarachnoid hemorrhage, Trigeminal Neuralgia, Cyclical migraine, Hemicrania continua, Intermittent hydrocephalus, Sleep apnea, Acute optic neuritis, Acute glaucoma, Acute hypertension, Cerebral venous thrombosis, and Interior carotid artery dissection.

Causes

Cluster headaches are generally associated with underlying neurologic conditions and structural abnormalities of brain and the pituitary gland. Common causes include; Chronic paroxysmal hemicrania (CPH), Subarachnoid hemorrhage, Trigeminal Neuralgia, Cyclical migraine, Hemicrania continua, Intermittent hydrocephalus, Sleep apnea, Acute optic neuritis, Acute glaucoma, Acute hypertension, Cerebral venous thrombosis, and Interior carotid artery dissection.

Cardiovascular Acute hypertension, Cerebral venous thrombosis, Interior carotid artery dissection
Chemical / poisoning No underlying causes
Dermatologic No underlying causes
Drug Side Effect No underlying causes
Ear Nose Throat Sinusitis
Endocrine Pheochromocytoma
Environmental Smoking or secondary exposure to tobacco smoke
Gastroenterologic No underlying causes
Genetic Monozygotic twins
Hematologic No underlying causes
Iatrogenic No underlying causes
Infectious Disease Herpes Zoster
Musculoskeletal / Ortho No underlying causes
Neurologic Chronic paroxysmal hemicrania (CPH), Subarachnoid hemorrhage, Trigeminal Neuralgia, Cyclical migraine, Hemicrania continua, Intermittent hydrocephalus, Sleep apnea
Nutritional / Metabolic No underlying causes
Obstetrics and Gynecology Preeclampsia
Oncologic Intracranial neoplasm
Opthalmologic Acute optic neuritis, Acute glaucoma
Overdose / Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal / Electrolyte No underlying causes
Rheum / Immune / Allergy Temporal Arteritis, Allergen exposure, Connective tissue disorder (e.g., systemic lupus erythematosus SLE)
Trauma Cranial trauma
Miscellaneous No underlying causes

References

Russell MB, Andersson PG, Thomsen LL (March 1995). "Familial occurrence of cluster headache". J. Neurol. Neurosurg. Psychiatry. 58 (3): 341–3. doi:10.1136/jnnp.58.3.341. PMC 1073373. PMID 7897418.

El Amrani M, Ducros A, Boulan P, Aidi S, Crassard I, Visy JM, Tournier-Lasserve E, Bousser MG (2002). "Familial cluster headache: a series of 186 index patients". Headache. 42 (10): 974–7. doi:10.1046/j.1526-4610.2002.02226.x. PMID 12453028.

Leone M, Russell MB, Rigamonti A, Attanasio A, Grazzi L, D'Amico D, Usai S, Bussone G (May 2001). "Increased familial risk of cluster headache". Neurology. 56 (9): 1233–6. doi:10.1212/wnl.56.9.1233. PMID 11342697.


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