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{{Drugbox|
<div style="float: right;">
|IUPAC_name = ''3-[9-chloro-6-(2-fluorophenyl)-4-hydroxy-3-oxo-2,5-diazabicyclo''<br />''[5.4.0]undeca-5,8,10,12-tetraen-2-yl]propanenitrile''
[[File:Cinolazepam.png|thumb|none|400px|This image is provided by the National Library of Medicine.]]</div>
| image = Cinolazepam.svg
__NOTOC__
| width=215
{{SI}}
| image2 = Cinolazepam3d.png
{{CMG}}
| CAS_number=75696-02-5
==Overview==
| ATC_prefix=N05
'''Cinolazepam'''<ref> US Patent 4388313 Novel 3-hydroxy-1,4-benzodiazepine-2-ones and process for the preparation thereof</ref> (marketed under the brand name '''Gerodorm''')<ref name=Gerodorm>{{cite web | url = http://www.lannacher.ro/gerodorm.html | title = Gerodorm | accessdate = 17 August 2006 | author = Lannacher Romania | year = 1999 | work = Produse Gerot inregistrate in Romania | language = Romanian |archiveurl = http://web.archive.org/web/20061011022835/http://www.lannacher.ro/gerodorm.html <!-- Bot retrieved archive --> |archivedate = 11 October 2006}}</ref> is a drug which is a [[benzodiazepine]] derivative. It possesses [[anxiolytic]], [[anticonvulsant]], [[sedative]] and [[skeletal muscle relaxant]] properties.
| ATC_suffix=CD13
Due to its strong sedative properties, it is primarily used as an [[hypnotic]].
| ATC_supplemental=
Cinolazepam is not approved for sale in the United States or Canada.
| PubChem=3033621
| DrugBank=?
| C=18 | H=13 | Cl=1 | F=1 | N=3 | O=2
| molecular_weight = 357.8
| bioavailability= 90-100%
| metabolism = [[Liver|Hepatic]]
| elimination_half-life= 9 h<ref name=half-life>{{cite journal | first = B. | last = Saletu | coauthors = G. Kindshofer, P. Anderer, J. Grunberger | year = 1987 | title = Short-term sleep laboratory studies with cinolazepam in situational insomnia induced by traffic noise. | journal = International Journal of Clinical Pharmacology Research | volume = 7 | issue = 5 | pages = 407-18 | id = {{PMID|2889679}} }}</ref>
| excretion =  [[Kidney|Renal]]
| pregnancy_category = ?
| legal_status = [[Schedule IV controlled substance|Schedule IV]](US)
| routes_of_administration= Oral
}}
'''Cinolazepam''' (Gerodorm®<ref name=Gerodorm>{{cite web | url = http://www.lannacher.ro/gerodorm.html | title = Gerodorm® | accessmonthday = 17 August | accessyear = 2006 | author = Lannacher Romania | year = 1999 | work = Produse Gerot inregistrate in Romania | language = Romanian}}</ref>) is a drug which is a [[benzodiazepine]] derivative. It possesses [[anxiolytic]], [[anticonvulsant]], [[sedative]] and [[skeletal muscle relaxant]] properties.


Cinolazepam is not approved for sale in the United States or Canada.
==See also==
*[[Benzodiazepine]]


==References==
==References==
<div class="references-small"><references/></div>
{{Reflist|2}}
==External links==
* [http://www.inchem.org/documents/pims/pharm/pim920.htm Inchem.org - Cinolazepam]


{{Benzodiazepines}}
{{Benzodiazepines}}
{{Hypnotics and sedatives}}
{{Hypnotics and sedatives}}
[[Category:Benzodiazepines]]
[[Category:Benzodiazepines]]
[[Category:Hypnotics]]
[[Category:Hypnotics]]
 
[[Category:Organochlorides]]
 
[[Category:Nitriles]]
{{pharma-stub}}
[[Category:Organofluorides]]
 
[[Category:Lactams]]
[[gl:Cinolazepam]]
[[Category:Alcohols]]
[[la:Cinolazepamum]]
[[Category:Drug]]
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Latest revision as of 14:47, 8 April 2015

This image is provided by the National Library of Medicine.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Cinolazepam[1] (marketed under the brand name Gerodorm)[2] is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. Due to its strong sedative properties, it is primarily used as an hypnotic. Cinolazepam is not approved for sale in the United States or Canada.

See also

References

  1. US Patent 4388313 Novel 3-hydroxy-1,4-benzodiazepine-2-ones and process for the preparation thereof
  2. Lannacher Romania (1999). "Gerodorm". Produse Gerot inregistrate in Romania (in Romanian). Archived from the original on 11 October 2006. Retrieved 17 August 2006.

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