Chikungunya differential diagnosis

Revision as of 20:37, 13 June 2014 by Alejandro Lemor (talk | contribs) (/* Comparison between Chikungunya and Dengue Fever Adapted from Clin Infect Dis. (2009) 49(6):942-948.{{cite journal|last1=Staples|first1=J. Erin|last2=Breiman|first2=Robert F.|last3=Powers|first3=Ann M.|title=Chikungunya Fever: An Epidemiological Revi...)
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2], Alonso Alvarado, M.D. [3]

Overview

Chikunguyna must be differentiated from other diseases that present with flu like symptoms such as fever, headache, fatigue, joint aches or arthralgias, myalgias. Diseases with similar symptoms include dengue, influenza, measles, rubella, malaria, and yellow fever.

Differential Diagnosis


Comparison between Chikungunya and Dengue Fever Adapted from Clin Infect Dis. (2009) 49(6):942-948.[1]


Clinical and laboratory findings of chikunguyna and dengue fever
Clinical Findings Chikungunya Dengue Fever
Fever (>102°F or 39°C) +++ ++
Headache ++ ++
Rash ++ +
Arthalgias +++ +/–
Myalgias + ++
Shock +/–
Bleeding dyscrasias +/– ++
Laboratory Findings
Elevated hematocrit ++
Leukopenia ++ +++
Neutropenia + +++
Lymphopenia +++ ++
Thrombocytopenia + +++
Mean frequency of symptoms from studies where the two diseases were directly compared among patient seeking care; +++ = 70-100% of patients; ++ = 40-69%; + = 10-39%; +/– = <10%; — = 0%[2][3]

References

  1. Staples, J. Erin; Breiman, Robert F.; Powers, Ann M. (2009). "Chikungunya Fever: An Epidemiological Review of a Re‐Emerging Infectious Disease". Clinical Infectious Diseases. 49 (6): 942–948. doi:10.1086/605496. ISSN 1058-4838.
  2. S. Nimmannitya, S. B. Halstead, S. N. Cohen & M. R. Margiotta (1969). "Dengue and chikungunya virus infection in man in Thailand, 1962-1964. I. Observations on hospitalized patients with hemorrhagic fever". The American journal of tropical medicine and hygiene. 18 (6): 954–971. PMID 5355242. Unknown parameter |month= ignored (help)
  3. Patrick Hochedez, Ana Canestri, Amelie Guihot, Segolene Brichler, Francois Bricaire & Eric Caumes (2008). "Management of travelers with fever and exanthema, notably dengue and chikungunya infections". The American journal of tropical medicine and hygiene. 78 (5): 710–713. PMID 18458301. Unknown parameter |month= ignored (help)

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