Cefalotin: Difference between revisions

Cefalotin
Clinical data
Pregnancy; category	AU: A ; ;
Routes of; administration	IV
ATC code	J01DB03 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only) ; UK: POM (Prescription only) ;
Pharmacokinetic data
Bioavailability	n/a
Protein binding	65 to 80%
Metabolism	Hepatic
Elimination half-life	30 minutes to 1 hour
Excretion	Renal
Identifiers
	IUPAC name (6R,7R)-3-(acetoxymethyl)-; 8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-; 1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid;
CAS Number	153-61-7;
PubChem CID	6024;
DrugBank	APRD00859;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C16H16N2O6S2
Molar mass	396.44 g/mol

VisualWikitext

Revision as of 19:10, 4 April 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Cefalotin (INN) (Template:PronEng) or cephalothin (USAN) (Template:IPA) is a first-generation cephalosporin antibiotic. It was the first cephalosporin marketed and continues to be widely used. It is an intravenously-administered agent with a similar antimicrobial spectrum to cefazolin and the oral agent cefalexin. Cefalotin sodium is commonly marketed under the trade name Keflin (Lilly).

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 | routes_of_administration = [[Intravenous therapy|IV]]
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-{{SI}}
+__NOTOC__
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 ==Overview==

v t e Antibacterials: cell wall disruption (J01C-J01D)
Internal to membrane/ (inhibit peptidoglycan subunit synthesis and transport)	Template:Navbox subgroup
Glycopeptide/ (inhibit PG chain elongation)	Vancomycin # (Oritavancin, Telavancin) · Teicoplanin (Dalbavancin) · Ramoplanin
Beta-lactams/ (inhibit cross-links with PBP)	Template:Navbox subgroup
Other	Template:Navbox subgroup
# = WHO-EM

Cefalotin: Difference between revisions

Revision as of 19:10, 4 April 2015

Overview

See also

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Clinical data
Pregnancy category	AU: A
Routes of administration	IV
ATC code	J01DB03 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) UK: POM (Prescription only)
Pharmacokinetic data
Bioavailability	n/a
Protein binding	65 to 80%
Metabolism	Hepatic
Elimination half-life	30 minutes to 1 hour
Excretion	Renal
Identifiers
IUPAC name (6R,7R)-3-(acetoxymethyl)- 8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia- 1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS Number	153-61-7
PubChem CID	6024
DrugBank	APRD00859
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₆H₁₆N₂O₆S₂
Molar mass	396.44 g/mol