Cavernous angioma history and symptoms: Difference between revisions
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==Overview== | |||
[[Cerebral cavernous malformations]] ([[CCM|CCM)]] have varying presentations and these can be in the form of [[hemorrhagic stroke]], [[focal neurological deficits]], recurrent [[headaches]], and [[seizures]]. Howevever, CCMs can be [[asymptomatic]] sometimes. <ref name="pmid30909834">{{cite journal| author=Zafar A, Quadri SA, Farooqui M, Ikram A, Robinson M, Hart BL | display-authors=etal| title=Familial Cerebral Cavernous Malformations. | journal=Stroke | year= 2019 | volume= 50 | issue= 5 | pages= 1294-1301 | pmid=30909834 | doi=10.1161/STROKEAHA.118.022314 | pmc=6924279 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30909834 }} </ref> | |||
==History and Symptoms== | |||
*This condition usually presents a significant amount of [[dilation of blood vessels]] lined by a single layer of [[endothelium]]. There is a lack of [[neuronal tissue]] interspersed within the lesion. | |||
*These thinly-walled [[vessels]] are comparable to [[sinusoidal]] cavities with stagnant [[blood]]. | |||
*The diameters of affected [[blood vessels]] in patients with [[CCM]] vary significantly, ranging from millimeters to centimeters. [[CCM]] lesions usually look like raspberries in [[gross appearance]]. | |||
*Patients with [[CCM]] can be [[asymptomatic]] or can have severe [[symptoms]] such as [[headaches]], [[paralysis|paralysis,]] [[seizures]], [[cerebral hemorrhage]], [[Hemorrhagic stroke|hemorrhagic stroke,]] or even [[death]]. | |||
*The nature and severity of the [[symptoms]] depend on the lesion's location in the [[brain]]. Approximately 70% of these [[lesions]] occur in the [[supratentorial]] region of the [[brain]]. | |||
*The remaining 30% occur in the [[infratentorial]] region. | |||
==References== | ==References== | ||
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[[Category:Genetic disorders]] | [[Category:Genetic disorders]] | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
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[[Category:Needs content]] | [[Category:Needs content]] | ||
Latest revision as of 20:51, 28 April 2022
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Edzel Lorraine Co, D.M.D., M.D.
Overview
Cerebral cavernous malformations (CCM) have varying presentations and these can be in the form of hemorrhagic stroke, focal neurological deficits, recurrent headaches, and seizures. Howevever, CCMs can be asymptomatic sometimes. [1]
History and Symptoms
- This condition usually presents a significant amount of dilation of blood vessels lined by a single layer of endothelium. There is a lack of neuronal tissue interspersed within the lesion.
- These thinly-walled vessels are comparable to sinusoidal cavities with stagnant blood.
- The diameters of affected blood vessels in patients with CCM vary significantly, ranging from millimeters to centimeters. CCM lesions usually look like raspberries in gross appearance.
- Patients with CCM can be asymptomatic or can have severe symptoms such as headaches, paralysis, seizures, cerebral hemorrhage, hemorrhagic stroke, or even death.
- The nature and severity of the symptoms depend on the lesion's location in the brain. Approximately 70% of these lesions occur in the supratentorial region of the brain.
- The remaining 30% occur in the infratentorial region.
References
- ↑ Zafar A, Quadri SA, Farooqui M, Ikram A, Robinson M, Hart BL; et al. (2019). "Familial Cerebral Cavernous Malformations". Stroke. 50 (5): 1294–1301. doi:10.1161/STROKEAHA.118.022314. PMC 6924279 Check
|pmc=value (help). PMID 30909834.