Cardiac amyloidosis echocardiography

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]: Aarti Narayan, M.B.B.S [3]; Cafer Zorkun, M.D., Ph.D. [4]

Overview

Transthoracic echocardiography is most commonly used in the initial evaluation of cardiac amyloidosis. The most common echocardiographic finding is thickening of the left ventricle.

Echocardiography

Findings on echocardiography include:[1]

  • Thickening of the left ventricle
  • Granular or sparkling appearance of the myocardium secondary to amyloid deposition int he myocardium. This finding is especially seen best with two dimentional echocardiography.
  • Thickening of interventricular septum
  • Diastolic dysfunction
  • Normal or reduced LV cavity
  • Pericardial effusion
  • RV hypertrophy
  • Left atrial enlargement
  • Thickened AV valves
  • Right ventricular dilatation (poor prognostic marker indicating right heart failure)

References

  1. Siqueira-Filho AG, Cunha CL, Tajik AJ, Seward JB, Schattenberg TT, Giuliani ER (1981). "M-mode and two-dimensional echocardiographic features in cardiac amyloidosis". Circulation. 63 (1): 188–96. PMID 7438392. Unknown parameter |month= ignored (help)


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