Capillary leak syndrome: Difference between revisions

	Capillary leak syndrome Microchapters
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Revision as of 19:38, 28 January 2013

For patient information, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and Keywords: Systemic capillary leak syndrome; SCLS; Clarkson's disease.

Generalized edema or anasarca

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-==Prognosis==
-Mortality is reported in 21% of the 57 cases described. However, better management of this condition has recently led to lower mortality.
-In the Mayo Clinic’s experience, the median survival of 25 patients that were followed over 30 years (counting only SCLS-related deaths) was approximately 15 years, and their 5-year survival rate was 76%.<ref name="druey"/><ref name="kapoor"/> In European experience, the 5-year post-diagnosis survival rate was 85% in 23 patients who had received prophylactic treatment and 20% in 5 patients who had not.<ref name="gousseff" /> However, better identification and management of this condition appears to be resulting in lower mortality and improving survival and quality-of-life results as of late.
 ==Diagnosis==