Capillary leak syndrome: Difference between revisions

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Latest revision as of 18:09, 16 November 2022

For patient information, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S

Synonyms and Keywords: Systemic capillary leak syndrome; SCLS; Clarkson's disease.

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Capillary leak syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

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-{{Infobox_Disease
+__NOTOC__
- | Name           = {{PAGENAME}}
- | Image          =
- | Caption        =
- | DiseasesDB     = 34090
- | ICD10          =
- | ICD9           =
- | ICDO           =
- | OMIM           =
- | MedlinePlus    =
- | eMedicineSubj  =
- | eMedicineTopic =
- | MeshID         = D019559
-}}
-{{SI}}
-{{CMG}}
-'''''Synonyms and Keywords:''''' Systemic Capillary Leak Syndrome, SCLS
+'''For patient information, click [[Capillary leak syndrome (patient information)|here]]'''
-==Overview==
+{{CMG}}; '''Associate Editor(s)-In-Chief:''' [https://www.wikidoc.org/index.php/User:Hassan_M M. Hassan, M.B.B.S]
-Capillary Leak Syndrome is a rare [[medical condition]] where the number and size of the [[pore]]s in the [[capillaries]] are increased which leads to a leakage of [[fluid]] from the [[blood]] to the [[interstitial fluid]], resulting in dangerously low [[blood pressure]] ([[hypotension]]), [[edema]] and multiple [[Organ (anatomy)|organ]] failure due to limited [[perfusion]].
+{{Capillary leak syndrome}}
-==Historical Perspective==
+'''''Synonyms and Keywords:''''' Systemic capillary leak syndrome; SCLS; Clarkson's disease.
-The [[syndrome]] was first described by Clarkson in 1960.
-==Diagnosis==
+==[[Capillary leak syndrome overview|Overview]]==
-===Symptoms===
-Generalized swelling may be present.
-===Physical Examination===
+==[[Capillary leak syndrome historical perspective|Historical Perspective]]==
-====Vitals====
+==[[Capillary leak syndrome pathophysiology|Pathophysiology]]==
-* Low blood pressure ([[hypotension]])
+==[[Capillary leak syndrome causes|Causes]]==
-====Skin====
-Generalized [[edema]] or [[anasarca]]
-===Laboratory Studies===
+==[[Capillary leak syndrome differential diagnosis|Differentiating Capillary leak syndrome from other Diseases]]==
-* Hemoconcentration
+==[[Capillary leak syndrome epidemiology and demographics|Epidemiology and Demographics]]==
-* [[Hypoalbuminemia]] without [[albuminuria]]
-==Natural hisotry==
+==[[Capillary leak syndrome risk factors|Risk Factors]]==
-The episode usually consists of two phases
-. The capillary leak phase (1-4 days)
+==[[Capillary leak syndrome natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
-The initial phase is the capillary leak phase, lasting from 1 to 4 days. Clinical features are [[abdominal pain]], [[nausea]], generalized edema and [[hypotension]] that may result in cardiopulmonary collapse. [[Acute renal failure]] is due to [[acute tubular necrosis]] consequent to [[hypovolemia]] and [[rhabdomyolysis]].
-. Recruitment of the interstitial fluid
+==Diagnosis==
-The second phase results in the recruitment of the initially extravasated fluid. Intravascular overload with [[polyuria]] and [[pulmonary edema]] often occur. Edema may be more severe due to massive fluid supply in the initial phase. It's necessary to monitor the patient in order to switch to depletion treatment with [[diuretics]] or [[hemofiltration]].
+[[Capillary leak syndrome history and symptoms|History and Symptoms]] | [[Capillary leak syndrome physical examination|Physical Examination]] | [[Capillary leak syndrome laboratory findings|Laboratory Findings]] | [[Capillary leak syndrome other diagnostic studies|Other Diagnostic Studies]]
 ==Treatment==
-A few [[prophylactic]] treatments have been tried with variable results, principally [[terbutaline]] and [[theophylline]].
-==Prognosis==
-Mortality is reported in 21% of the 57 cases described. However, better management of this condition has recently led to lower mortality.
-==References==
-* Dorlands Medical Dictionary 30th Ed.
-* [http://www.cancer.gov/Templates/db_alpha.aspx?CdrID=426421 Cancer.gov]
-* [http://ndt.oxfordjournals.org/cgi/content/full/17/3/492 Case report in Oxford Journals]
-* [http://www.orpha.net/static/GB/capillary_leak_syndrome.html Orphanet (2003)]
+[[Capillary leak syndrome medical therapy|Medical Therapy]] | [[Capillary leak syndrome prevention|Prevention]] | [[Capillary leak syndrome cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Capillary leak syndrome future or investigational therapies|Future or Investigational Therapies]]
-{{SIB}}
+==Case Studies==
+[[Capillary leak syndrome case study one|Case #1]]
 [[Category:Syndromes]]
 [[Category:Intensive care medicine]]
 [[Category:Emergency medicine]]
+[[Category:Disease]]
 {{WikiDoc Help Menu}}
-{{WS}}

Capillary leak syndrome: Difference between revisions

Latest revision as of 18:09, 16 November 2022

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