Capillary leak syndrome: Difference between revisions

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==[[Capillary leak syndrome historical perspective|Historical Perspective]]==
==[[Capillary leak syndrome historical perspective|Historical Perspective]]==
==[[Capillary leak syndrome pathophysiology|Pathophysiology]]==
==[[Capillary leak syndrome pathophysiology|Pathophysiology]]==
The pathogenesis of capillary leak syndrome remain unclear, however, '''[https://www.wikidoc.org/index.php/Cytokines cytokines]''', '''[https://www.wikidoc.org/index.php/Vascular_endothelial_growth_factor vascular endothelial growth factor]''' (VEGF), '''[https://www.wikidoc.org/index.php/Leukotrienes leukotrienes]''', and '''complement''' play an important role.  During each episode of hyperpermeability of the vasculature, there is an increase of interleukin 2 receptor-positive peripheral blood M-cell count, as well as apoptosis of the endothelial cells.
==[[Capillary leak syndrome causes|Causes]]==
==[[Capillary leak syndrome causes|Causes]]==


==[[Capillary leak syndrome differential diagnosis|Differentiating Capillary leak syndrome from other Diseases]]==
==[[Capillary leak syndrome differential diagnosis|Differentiating Capillary leak syndrome from other Diseases]]==
As capillary leak syndrome has overlapping clinical and laboratory findings with various other conditions, it should be considered as the diagnosis of exclusion.  Several conditions that may be considered as the differential diagnoses of capillary leak syndrome include [https://www.wikidoc.org/index.php/Polycythemia%20vera polycythemia vera], [https://www.wikidoc.org/index.php/Hereditary%20angioedema hereditary angioedema], Gleich syndrome, [https://www.wikidoc.org/index.php/Adrenal%20insufficiency adrenal insufficiency], [https://www.wikidoc.org/index.php/Mast%20cell%20tumor mast cell disease], [https://www.wikidoc.org/index.php/Acute%20gastroenteritis acute gastroenteritis], [https://www.wikidoc.org/index.php/Carcinoid%20syndrome carcinoid syndrome], [https://www.wikidoc.org/index.php/Primary%20amyloidosis primary amyloidosis], [https://www.wikidoc.org/index.php/Chronic%20heart%20failure chronic heart failure], [https://www.wikidoc.org/index.php/Sepsis sepsis], and [https://www.wikidoc.org/index.php/Toxic%20shock%20syndrome toxic shock syndrome].
==[[Capillary leak syndrome epidemiology and demographics|Epidemiology and Demographics]]==
==[[Capillary leak syndrome epidemiology and demographics|Epidemiology and Demographics]]==


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S

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Synonyms and Keywords: Systemic capillary leak syndrome; SCLS; Clarkson's disease.

Overview

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Treatment

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