Capillary leak syndrome: Difference between revisions

	Capillary leak syndrome Microchapters
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Latest revision as of 18:09, 16 November 2022

For patient information, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S

Synonyms and Keywords: Systemic capillary leak syndrome; SCLS; Clarkson's disease.

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 ==[[Capillary leak syndrome historical perspective|Historical Perspective]]==
-Capillary leak syndrome was first described by B. Clarkson in 1960, and was named after him.
-Numerous case reports on capillary leak syndrome are published since then.
-Between 1960 to 2006, a hundred cases of capillary leak syndrome were reported in the world literature, and additional 26 cases were published since 2006.
 ==[[Capillary leak syndrome pathophysiology|Pathophysiology]]==
-The pathogenesis of capillary leak syndrome remain unclear, however, '''cytokines''', '''vascular endothelial growth factor''' (VEGF), '''leukotrienes''', and '''complement''' play an important role. During each episode of hyperpermeability of the vasculature, there is an increase of interleukin 2 receptor-positive peripheral blood M-cell count, as well as apoptosis of the endothelial cells.
 ==[[Capillary leak syndrome causes|Causes]]==
 ==[[Capillary leak syndrome differential diagnosis|Differentiating Capillary leak syndrome from other Diseases]]==
 ==[[Capillary leak syndrome epidemiology and demographics|Epidemiology and Demographics]]==
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