CSN3 (gene): Difference between revisions

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{{Infobox_gene}}
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'''Kappa-casein''' is a [[protein]] that in humans is encoded by the ''CSN3'' [[gene]].<ref name="pmid8863730">{{cite journal | vauthors = Edlund A, Johansson T, Leidvik B, Hansson L | title = Structure of the human kappa-casein gene | journal = Gene | volume = 174 | issue = 1 | pages = 65–9 |date=Nov 1996 | pmid = 8863730 | pmc =  | doi =10.1016/0378-1119(96)00351-4 }}</ref><ref name="pmid9050925">{{cite journal | vauthors = Fujiwara Y, Miwa M, Nogami M, Okumura K, Nobori T, Suzuki T, Ueda M | title = Genomic organization and chromosomal localization of the human casein gene family | journal = Hum Genet | volume = 99 | issue = 3 | pages = 368–73 |date=Mar 1997 | pmid = 9050925 | pmc =  | doi =10.1007/s004390050374 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CSN3 casein kappa| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1448| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Casein kappa
| HGNCid = 2446
| Symbol = CSN3
| AltSymbols =; CSN10
| OMIM = 601695
| ECnumber =
| Homologene = 3818
| MGIid = 107461
  | GeneAtlas_image1 = PBB_GE_CSN3_207803_s_at_tn.png
  | Function = {{GNF_GO|id=GO:0003674 |text = molecular_function}}  
| Component = {{GNF_GO|id=GO:0005576 |text = extracellular region}}
| Process =  
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 1448
    | Hs_Ensembl = ENSG00000171209
    | Hs_RefseqProtein = NP_005203
    | Hs_RefseqmRNA = NM_005212
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 4
    | Hs_GenLoc_start = 71142894
    | Hs_GenLoc_end = 71151732
    | Hs_Uniprot = P07498
    | Mm_EntrezGene = 12994
    | Mm_Ensembl = ENSMUSG00000001622
    | Mm_RefseqmRNA = NM_007786
    | Mm_RefseqProtein = NP_031812
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 5
    | Mm_GenLoc_start = 89000168
    | Mm_GenLoc_end = 89007089
    | Mm_Uniprot = Q9D1U2
  }}
}}
'''Casein kappa''', also known as '''CSN3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CSN3 casein kappa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1448| accessdate = }}</ref>


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==Interactions==
CSN3 (gene) has been shown to [[Protein-protein interaction|interact]] with [[EIF3S6]].<ref name=pmid12220626>{{cite journal |doi=10.1016/S0014-5793(02)03147-2 |last=Hoareau Alves |first=Karine |author2=Bochard Valérie |author3=Réty Stéphane |author4=Jalinot Pierre  |date=Sep 2002 |title=Association of the mammalian proto-oncoprotein Int-6 with the three protein complexes eIF3, COP9 signalosome and 26S proteasome |journal=FEBS Lett. |volume=527 |issue=1-3 |pages=15–21 |publisher= |location = Netherlands| issn = 0014-5793| pmid = 12220626 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==External links==
* {{UCSC gene info|CSN3}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Bergström S, Hansson L, Hernell O, ''et al.'' |title=Cloning and sequencing of human kappa-casein cDNA. |journal=DNA Seq. |volume=3 |issue= 4 |pages= 245-6 |year= 1993 |pmid= 1296818 |doi=  }}
*{{cite journal  | vauthors=Bergström S, Hansson L, Hernell O |title=Cloning and sequencing of human kappa-casein cDNA. |journal=DNA Seq. |volume=3 |issue= 4 |pages= 245–6 |year= 1993 |pmid= 1296818 |doi=10.3109/10425179209034024 |display-authors=etal}}
*{{cite journal  | author=Brignon G, Chtourou A, Ribadeau-Dumas B |title=Preparation and amino acid sequence of human kappa-casein. |journal=FEBS Lett. |volume=188 |issue= 1 |pages= 48-54 |year= 1985 |pmid= 4018271 |doi=  }}
*{{cite journal  | vauthors=Brignon G, Chtourou A, Ribadeau-Dumas B |title=Preparation and amino acid sequence of human kappa-casein. |journal=FEBS Lett. |volume=188 |issue= 1 |pages= 48–54 |year= 1985 |pmid= 4018271 |doi=10.1016/0014-5793(85)80872-3 }}
*{{cite journal  | author=Fiat AM, Jollès J, Aubert JP, ''et al.'' |title=Localisation and importance of the sugar part of human casein. |journal=Eur. J. Biochem. |volume=111 |issue= 2 |pages= 333-9 |year= 1981 |pmid= 7460900 |doi= }}
*{{cite journal  | vauthors=Fiat AM, Jollès J, Aubert JP |title=Localisation and importance of the sugar part of human casein. |journal=Eur. J. Biochem. |volume=111 |issue= 2 |pages= 333–9 |year= 1981 |pmid= 7460900 |doi=10.1111/j.1432-1033.1980.tb04946.|display-authors=etal}}
*{{cite journal  | author=Edlund A, Johansson T, Leidvik B, Hansson L |title=Structure of the human kappa-casein gene. |journal=Gene |volume=174 |issue= 1 |pages= 65-9 |year= 1996 |pmid= 8863730 |doi=  }}
*{{cite journal  | vauthors=Plowman JE, Creamer LK, Liddell MJ, Cross JJ |title=Structural features of a peptide corresponding to human kappa-casein residues 84-101 by 1H-nuclear magnetic resonance spectroscopy. |journal=J. Dairy Res. |volume=66 |issue= 1 |pages= 53–63 |year= 1999 |pmid= 10191473 |doi=10.1017/S0022029998003318 }}
*{{cite journal  | author=Fujiwara Y, Miwa M, Nogami M, ''et al.'' |title=Genomic organization and chromosomal localization of the human casein gene family. |journal=Hum. Genet. |volume=99 |issue= 3 |pages= 368-73 |year= 1997 |pmid= 9050925 |doi= }}
*{{cite journal  | vauthors=Harrington JJ, Sherf B, Rundlett S |title=Creation of genome-wide protein expression libraries using random activation of gene expression. |journal=Nat. Biotechnol. |volume=19 |issue= 5 |pages= 440–5 |year= 2001 |pmid= 11329013 |doi= 10.1038/88107 |display-authors=etal}}
*{{cite journal  | author=Plowman JE, Creamer LK, Liddell MJ, Cross JJ |title=Structural features of a peptide corresponding to human kappa-casein residues 84-101 by 1H-nuclear magnetic resonance spectroscopy. |journal=J. Dairy Res. |volume=66 |issue= 1 |pages= 53-63 |year= 1999 |pmid= 10191473 |doi=  }}
*{{cite journal  | vauthors=Benítez MJ, Cochet C, Jiménez JS |title=A surface plasmon resonance study of the interactions between the component subunits of protein kinase CK2 and two protein substrates, casein and calmodulin. |journal=Mol. Cell. Biochem. |volume=227 |issue= 1-2 |pages= 31–6 |year= 2002 |pmid= 11827172 |doi=10.1023/A:1013140220121 }}
*{{cite journal  | author=Harrington JJ, Sherf B, Rundlett S, ''et al.'' |title=Creation of genome-wide protein expression libraries using random activation of gene expression. |journal=Nat. Biotechnol. |volume=19 |issue= 5 |pages= 440-5 |year= 2001 |pmid= 11329013 |doi= 10.1038/88107 }}
*{{cite journal  | vauthors=Sood SM, Slatter CW |title=Suspension of the calcium-sensitive human beta-caseins by human kappa-casein. |journal=J. Dairy Sci. |volume=85 |issue= 6 |pages= 1353–6 |year= 2003 |pmid= 12146463 |doi=10.3168/jds.S0022-0302(02)74200-8 }}
*{{cite journal  | author=Benítez MJ, Cochet C, Jiménez JS |title=A surface plasmon resonance study of the interactions between the component subunits of protein kinase CK2 and two protein substrates, casein and calmodulin. |journal=Mol. Cell. Biochem. |volume=227 |issue= 1-2 |pages= 31-6 |year= 2002 |pmid= 11827172 |doi=  }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Sood SM, Slatter CW |title=Suspension of the calcium-sensitive human beta-caseins by human kappa-casein. |journal=J. Dairy Sci. |volume=85 |issue= 6 |pages= 1353-6 |year= 2003 |pmid= 12146463 |doi=  }}
*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Kim YJ, Park S, Oh YK |title=Purification and characterization of human caseinomacropeptide produced by a recombinant Saccharomyces cerevisiae. |journal=Protein Expr. Purif. |volume=41 |issue= 2 |pages= 441–6 |year= 2005 |pmid= 15866733 |doi= 10.1016/j.pep.2005.02.021 |display-authors=etal}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |display-authors=etal}}
*{{cite journal  | author=Kim YJ, Park S, Oh YK, ''et al.'' |title=Purification and characterization of human caseinomacropeptide produced by a recombinant Saccharomyces cerevisiae. |journal=Protein Expr. Purif. |volume=41 |issue= 2 |pages= 441-6 |year= 2005 |pmid= 15866733 |doi= 10.1016/j.pep.2005.02.021 }}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
}}
}}
{{refend}}
{{refend}}


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Revision as of 10:07, 30 August 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Kappa-casein is a protein that in humans is encoded by the CSN3 gene.[1][2][3]


Interactions

CSN3 (gene) has been shown to interact with EIF3S6.[4]

References

  1. Edlund A, Johansson T, Leidvik B, Hansson L (Nov 1996). "Structure of the human kappa-casein gene". Gene. 174 (1): 65–9. doi:10.1016/0378-1119(96)00351-4. PMID 8863730.
  2. Fujiwara Y, Miwa M, Nogami M, Okumura K, Nobori T, Suzuki T, Ueda M (Mar 1997). "Genomic organization and chromosomal localization of the human casein gene family". Hum Genet. 99 (3): 368–73. doi:10.1007/s004390050374. PMID 9050925.
  3. "Entrez Gene: CSN3 casein kappa".
  4. Hoareau Alves, Karine; Bochard Valérie; Réty Stéphane; Jalinot Pierre (Sep 2002). "Association of the mammalian proto-oncoprotein Int-6 with the three protein complexes eIF3, COP9 signalosome and 26S proteasome". FEBS Lett. Netherlands. 527 (1–3): 15–21. doi:10.1016/S0014-5793(02)03147-2. ISSN 0014-5793. PMID 12220626.

External links

Further reading