CLDN9: Difference between revisions

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Revision as of 03:04, 15 November 2017

Claudin-9 is a protein that in humans is encoded by the CLDN9 gene.^[1]^[2]^[3] It belongs to the group of claudins.

This gene is involved in hearing.^[4]

References

↑ Peacock RE, Keen TJ, Inglehearn CF (Mar 1998). "Analysis of a human gene homologous to rat ventral prostate.1 protein". Genomics. 46 (3): 443–9. doi:10.1006/geno.1997.5033. PMID 9441748.
↑ Meertens L, Bertaux C, Cukierman L, Cormier E, Lavillette D, Cosset FL, Dragic T (Mar 2008). "The tight junction proteins claudin-1, -6, and -9 are entry cofactors for hepatitis C virus". J Virol. 82 (7): 3555–60. doi:10.1128/JVI.01977-07. PMC 2268462. PMID 18234789.
↑ "Entrez Gene: CLDN9 claudin 9".
↑ Gene discovery reveals a critical protein's function in hearing

External links

Human CLDN9 genome location and CLDN9 gene details page in the UCSC Genome Browser.

Kniesel U, Wolburg H (2000). "Tight junctions of the blood–brain barrier". Cell. Mol. Neurobiol. 20 (1): 57–76. doi:10.1023/A:1006995910836. PMID 10690502.
Heiskala M, Peterson PA, Yang Y (2001). "The roles of claudin superfamily proteins in paracellular transport". Traffic. 2 (2): 93–8. doi:10.1034/j.1600-0854.2001.020203.x. PMID 11247307.
Tsukita S, Furuse M, Itoh M (2001). "Multifunctional strands in tight junctions". Nat. Rev. Mol. Cell Biol. 2 (4): 285–93. doi:10.1038/35067088. PMID 11283726.
Tsukita S, Furuse M (2003). "Claudin-based barrier in simple and stratified cellular sheets". Curr. Opin. Cell Biol. 14 (5): 531–6. doi:10.1016/S0955-0674(02)00362-9. PMID 12231346.
González-Mariscal L, Betanzos A, Nava P, Jaramillo BE (2003). "Tight junction proteins". Prog. Biophys. Mol. Biol. 81 (1): 1–44. doi:10.1016/S0079-6107(02)00037-8. PMID 12475568.
Yi X, Wang Y, Yu FS (2000). "Corneal epithelial tight junctions and their response to lipopolysaccharide challenge". Invest. Ophthalmol. Vis. Sci. 41 (13): 4093–100. PMID 11095601.
Kiuchi-Saishin Y, Gotoh S, Furuse M, et al. (2002). "Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments". J. Am. Soc. Nephrol. 13 (4): 875–86. PMID 11912246.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Katoh M, Katoh M (2004). "CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family". Int. J. Mol. Med. 11 (6): 683–9. doi:10.3892/ijmm.11.6.683. PMID 12736707.
Ban Y, Dota A, Cooper LJ, et al. (2003). "Tight junction-related protein expression and distribution in human corneal epithelium". Exp. Eye Res. 76 (6): 663–9. doi:10.1016/S0014-4835(03)00054-X. PMID 12742348.
Kitajiri SI, Furuse M, Morita K, et al. (2004). "Expression patterns of claudins, tight junction adhesion molecules, in the inner ear". Hear. Res. 187 (1–2): 25–34. doi:10.1016/S0378-5955(03)00338-1. PMID 14698084.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Zheng A, Yuan F, Li Y, et al. (2007). "Claudin-6 and claudin-9 function as additional coreceptors for hepatitis C virus". J. Virol. 81 (22): 12465–71. doi:10.1128/JVI.01457-07. PMC 2169001. PMID 17804490.
Liu F, Koval M, Ranganathan S, Fanayan S, Hancock WS, Lundberg EK, Beavis RC, Lane L, Duek P, McQuade L, Kelleher NL, Baker MS (2015). "A systems proteomics view of the endogenous human claudin protein family". J Proteome Res. doi:10.1021/acs.jproteome.5b00769. PMID 26680015.

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.

[pmid9441748-1] Peacock RE, Keen TJ, Inglehearn CF (Mar 1998). "Analysis of a human gene homologous to rat ventral prostate.1 protein". Genomics. 46 (3): 443–9. doi:10.1006/geno.1997.5033. PMID 9441748.

[pmid18234789-2] Meertens L, Bertaux C, Cukierman L, Cormier E, Lavillette D, Cosset FL, Dragic T (Mar 2008). "The tight junction proteins claudin-1, -6, and -9 are entry cofactors for hepatitis C virus". J Virol. 82 (7): 3555–60. doi:10.1128/JVI.01977-07. PMC 2268462. PMID 18234789.

[entrez-3] "Entrez Gene: CLDN9 claudin 9".

[4] Gene discovery reveals a critical protein's function in hearing

[1]

[2]

[3]

[4]

@@ Line 1: / Line 1: @@
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+{{Infobox_gene}}
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+'''Claudin-9''' is a [[protein]] that in humans is encoded by the ''CLDN9'' [[gene]].<ref name="pmid9441748">{{cite journal | vauthors = Peacock RE, Keen TJ, Inglehearn CF | title = Analysis of a human gene homologous to rat ventral prostate.1 protein | journal = Genomics | volume = 46 | issue = 3 | pages = 443–9 |date=Mar 1998 | pmid = 9441748 | pmc =  | doi = 10.1006/geno.1997.5033 }}</ref><ref name="pmid18234789">{{cite journal | vauthors = Meertens L, Bertaux C, Cukierman L, Cormier E, Lavillette D, Cosset FL, Dragic T | title = The tight junction proteins claudin-1, -6, and -9 are entry cofactors for hepatitis C virus | journal = J Virol | volume = 82 | issue = 7 | pages = 3555–60 |date=Mar 2008 | pmid = 18234789 | pmc = 2268462 | doi = 10.1128/JVI.01977-07 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CLDN9 claudin 9| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9080| accessdate = }}</ref> It belongs to the group of [[claudin]]s.
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- | image =
- | image_source =
- | PDB =
- | Name = Claudin 9
- | HGNCid = 2051
- | Symbol = CLDN9
- | AltSymbols =;
- | OMIM =
- | ECnumber =
-  | Homologene = 10656
- | MGIid = 1913100
- | GeneAtlas_image1 = PBB_GE_CLDN9_214635_at_tn.png
- | Function = {{GNF_GO|id=GO:0005198 |text = structural molecule activity}} {{GNF_GO|id=GO:0042802 |text = identical protein binding}}
- | Component = {{GNF_GO|id=GO:0005923 |text = tight junction}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
- | Process = {{GNF_GO|id=GO:0016338 |text = calcium-independent cell-cell adhesion}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 9080
-    | Hs_Ensembl = ENSG00000178709
-    | Hs_RefseqProtein = NP_066192
-    | Hs_RefseqmRNA = NM_020982
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 16
-    | Hs_GenLoc_start = 3002458
-    | Hs_GenLoc_end = 3004507
-    | Hs_Uniprot = O95484
-    | Mm_EntrezGene = 56863
-    | Mm_Ensembl = ENSMUSG00000066720
-    | Mm_RefseqmRNA = NM_020293
-    | Mm_RefseqProtein = NP_064689
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 17
-    | Mm_GenLoc_start = 23410618
-    | Mm_GenLoc_end = 23411271
-    | Mm_Uniprot = Q6PEA4
-  }}
-}}
-'''Claudin 9''', also known as '''CLDN9''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CLDN9 claudin 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9080| accessdate = }}</ref>
+This gene is involved in hearing.<ref>[http://www.physorg.com/news170065521.html Gene discovery reveals a critical protein's function in hearing]</ref>
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 {{PBB_Summary
@@ Line 55: / Line 10: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
+==External links==
+* {{UCSC gene info|CLDN9}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Kniesel U, Wolburg H |title=Tight junctions of the blood-brain barrier. |journal=Cell. Mol. Neurobiol. |volume=20 |issue= 1 |pages= 57-76 |year= 2000 |pmid= 10690502 |doi=  }}
+*{{cite journal  | vauthors=Kniesel U, Wolburg H |title=Tight junctions of the blood–brain barrier. |journal=Cell. Mol. Neurobiol. |volume=20 |issue= 1 |pages= 57–76 |year= 2000 |pmid= 10690502 |doi=10.1023/A:1006995910836  }}
-*{{cite journal  | author=Heiskala M, Peterson PA, Yang Y |title=The roles of claudin superfamily proteins in paracellular transport. |journal=Traffic |volume=2 |issue= 2 |pages= 93-8 |year= 2001 |pmid= 11247307 |doi=  }}
+*{{cite journal  | vauthors=Heiskala M, Peterson PA, Yang Y |title=The roles of claudin superfamily proteins in paracellular transport. |journal=Traffic |volume=2 |issue= 2 |pages= 93–8 |year= 2001 |pmid= 11247307 |doi=10.1034/j.1600-0854.2001.020203.x  }}
-*{{cite journal  | author=Tsukita S, Furuse M, Itoh M |title=Multifunctional strands in tight junctions. |journal=Nat. Rev. Mol. Cell Biol. |volume=2 |issue= 4 |pages= 285-93 |year= 2001 |pmid= 11283726 |doi= 10.1038/35067088 }}
+*{{cite journal  | vauthors=Tsukita S, Furuse M, Itoh M |title=Multifunctional strands in tight junctions. |journal=Nat. Rev. Mol. Cell Biol. |volume=2 |issue= 4 |pages= 285–93 |year= 2001 |pmid= 11283726 |doi= 10.1038/35067088 }}
-*{{cite journal  | author=Tsukita S, Furuse M |title=Claudin-based barrier in simple and stratified cellular sheets. |journal=Curr. Opin. Cell Biol. |volume=14 |issue= 5 |pages= 531-6 |year= 2003 |pmid= 12231346 |doi=  }}
+*{{cite journal  | vauthors=Tsukita S, Furuse M |title=Claudin-based barrier in simple and stratified cellular sheets. |journal=Curr. Opin. Cell Biol. |volume=14 |issue= 5 |pages= 531–6 |year= 2003 |pmid= 12231346 |doi=10.1016/S0955-0674(02)00362-9  }}
-*{{cite journal  | author=González-Mariscal L, Betanzos A, Nava P, Jaramillo BE |title=Tight junction proteins. |journal=Prog. Biophys. Mol. Biol. |volume=81 |issue= 1 |pages= 1-44 |year= 2003 |pmid= 12475568 |doi=  }}
+*{{cite journal  | vauthors=González-Mariscal L, Betanzos A, Nava P, Jaramillo BE |title=Tight junction proteins. |journal=Prog. Biophys. Mol. Biol. |volume=81 |issue= 1 |pages= 1–44 |year= 2003 |pmid= 12475568 |doi=10.1016/S0079-6107(02)00037-8  }}
-*{{cite journal  | author=Peacock RE, Keen TJ, Inglehearn CF |title=Analysis of a human gene homologous to rat ventral prostate.1 protein. |journal=Genomics |volume=46 |issue= 3 |pages= 443-9 |year= 1998 |pmid= 9441748 |doi= 10.1006/geno.1997.5033 }}
+*{{cite journal  | vauthors=Yi X, Wang Y, Yu FS |title=Corneal epithelial tight junctions and their response to lipopolysaccharide challenge. |journal=Invest. Ophthalmol. Vis. Sci. |volume=41 |issue= 13 |pages= 4093–100 |year= 2000 |pmid= 11095601 |doi=  }}
-*{{cite journal  | author=Yi X, Wang Y, Yu FS |title=Corneal epithelial tight junctions and their response to lipopolysaccharide challenge. |journal=Invest. Ophthalmol. Vis. Sci. |volume=41 |issue= 13 |pages= 4093-100 |year= 2000 |pmid= 11095601 |doi=  }}
+*{{cite journal  | vauthors=Kiuchi-Saishin Y, Gotoh S, Furuse M |title=Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments. |journal=J. Am. Soc. Nephrol. |volume=13 |issue= 4 |pages= 875–86 |year= 2002 |pmid= 11912246 |doi=  |display-authors=etal}}
-*{{cite journal  | author=Kiuchi-Saishin Y, Gotoh S, Furuse M, ''et al.'' |title=Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments. |journal=J. Am. Soc. Nephrol. |volume=13 |issue= 4 |pages= 875-86 |year= 2002 |pmid= 11912246 |doi=  }}
+*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |display-authors=etal}}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  | vauthors=Katoh M, Katoh M |title=CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family. |journal=Int. J. Mol. Med. |volume=11 |issue= 6 |pages= 683–9 |year= 2004 |pmid= 12736707 |doi=  10.3892/ijmm.11.6.683}}
-*{{cite journal  | author=Katoh M, Katoh M |title=CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family. |journal=Int. J. Mol. Med. |volume=11 |issue= 6 |pages= 683-9 |year= 2004 |pmid= 12736707 |doi=  }}
+*{{cite journal  | vauthors=Ban Y, Dota A, Cooper LJ |title=Tight junction-related protein expression and distribution in human corneal epithelium. |journal=Exp. Eye Res. |volume=76 |issue= 6 |pages= 663–9 |year= 2003 |pmid= 12742348 |doi=10.1016/S0014-4835(03)00054-X  |display-authors=etal}}
-*{{cite journal  | author=Ban Y, Dota A, Cooper LJ, ''et al.'' |title=Tight junction-related protein expression and distribution in human corneal epithelium. |journal=Exp. Eye Res. |volume=76 |issue= 6 |pages= 663-9 |year= 2003 |pmid= 12742348 |doi=  }}
+*{{cite journal  | vauthors=Kitajiri SI, Furuse M, Morita K |title=Expression patterns of claudins, tight junction adhesion molecules, in the inner ear. |journal=Hear. Res. |volume=187 |issue= 1-2 |pages= 25–34 |year= 2004 |pmid= 14698084 |doi=10.1016/S0378-5955(03)00338-1  |display-authors=etal}}
-*{{cite journal  | author=Kitajiri SI, Furuse M, Morita K, ''et al.'' |title=Expression patterns of claudins, tight junction adhesion molecules, in the inner ear. |journal=Hear. Res. |volume=187 |issue= 1-2 |pages= 25-34 |year= 2004 |pmid= 14698084 |doi=  }}
+*{{cite journal  | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 |display-authors=etal}}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal  | vauthors=Zheng A, Yuan F, Li Y |title=Claudin-6 and claudin-9 function as additional coreceptors for hepatitis C virus. |journal=J. Virol. |volume=81 |issue= 22 |pages= 12465–71 |year= 2007 |pmid= 17804490 |doi= 10.1128/JVI.01457-07  | pmc=2169001 |display-authors=etal}}
-*{{cite journal  | author=Zheng A, Yuan F, Li Y, ''et al.'' |title=Claudin-6 and claudin-9 function as additional coreceptors for hepatitis C virus. |journal=J. Virol. |volume=81 |issue= 22 |pages= 12465-71 |year= 2007 |pmid= 17804490 |doi= 10.1128/JVI.01457-07 }}
 }}
+* {{cite journal | vauthors = Liu F, Koval M, Ranganathan S, Fanayan S, Hancock WS, Lundberg EK, Beavis RC, Lane L, Duek P, McQuade L, Kelleher NL, Baker MS | title = A systems proteomics view of the endogenous human claudin protein family | journal = J Proteome Res | date= 2015 | pmid = 26680015 | doi = 10.1021/acs.jproteome.5b00769 }}
 {{refend}}
-{{protein-stub}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
-{{WikiDoc Sources}}
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
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+| update_citations = yes
+}}
+{{gene-16-stub}}

CLDN9: Difference between revisions

Revision as of 03:04, 15 November 2017

References

External links

Further reading

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