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{{Infobox_gene}}
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'''Claudin-9''' is a [[protein]] that in humans is encoded by the ''CLDN9'' [[gene]].<ref name="pmid9441748">{{cite journal | vauthors = Peacock RE, Keen TJ, Inglehearn CF | title = Analysis of a human gene homologous to rat ventral prostate.1 protein | journal = Genomics | volume = 46 | issue = 3 | pages = 443–9 |date=Mar 1998 | pmid = 9441748 | pmc =  | doi = 10.1006/geno.1997.5033 }}</ref><ref name="pmid18234789">{{cite journal | vauthors = Meertens L, Bertaux C, Cukierman L, Cormier E, Lavillette D, Cosset FL, Dragic T | title = The tight junction proteins claudin-1, -6, and -9 are entry cofactors for hepatitis C virus | journal = J Virol | volume = 82 | issue = 7 | pages = 3555–60 |date=Mar 2008 | pmid = 18234789 | pmc = 2268462 | doi = 10.1128/JVI.01977-07 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CLDN9 claudin 9| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9080| accessdate = }}</ref> It belongs to the group of [[claudin]]s.
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{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = Claudin 9
| HGNCid = 2051
| Symbol = CLDN9
| AltSymbols =;
| OMIM =
| ECnumber =
  | Homologene = 10656
| MGIid = 1913100
| GeneAtlas_image1 = PBB_GE_CLDN9_214635_at_tn.png
| Function = {{GNF_GO|id=GO:0005198 |text = structural molecule activity}} {{GNF_GO|id=GO:0042802 |text = identical protein binding}}
| Component = {{GNF_GO|id=GO:0005923 |text = tight junction}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0016338 |text = calcium-independent cell-cell adhesion}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9080
    | Hs_Ensembl = ENSG00000178709
    | Hs_RefseqProtein = NP_066192
    | Hs_RefseqmRNA = NM_020982
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 16
    | Hs_GenLoc_start = 3002458
    | Hs_GenLoc_end = 3004507
    | Hs_Uniprot = O95484
    | Mm_EntrezGene = 56863
    | Mm_Ensembl = ENSMUSG00000066720
    | Mm_RefseqmRNA = NM_020293
    | Mm_RefseqProtein = NP_064689
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 17
    | Mm_GenLoc_start = 23410618
    | Mm_GenLoc_end = 23411271
    | Mm_Uniprot = Q6PEA4
  }}
}}
'''Claudin 9''', also known as '''CLDN9''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CLDN9 claudin 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9080| accessdate = }}</ref>


This gene is involved in hearing.<ref>[http://www.physorg.com/news170065521.html Gene discovery reveals a critical protein's function in hearing]</ref>
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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==External links==
* {{UCSC gene info|CLDN9}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Kniesel U, Wolburg H |title=Tight junctions of the blood-brain barrier. |journal=Cell. Mol. Neurobiol. |volume=20 |issue= 1 |pages= 57-76 |year= 2000 |pmid= 10690502 |doi=  }}
*{{cite journal  | vauthors=Kniesel U, Wolburg H |title=Tight junctions of the blood–brain barrier. |journal=Cell. Mol. Neurobiol. |volume=20 |issue= 1 |pages= 57–76 |year= 2000 |pmid= 10690502 |doi=10.1023/A:1006995910836 }}
*{{cite journal  | author=Heiskala M, Peterson PA, Yang Y |title=The roles of claudin superfamily proteins in paracellular transport. |journal=Traffic |volume=2 |issue= 2 |pages= 93-8 |year= 2001 |pmid= 11247307 |doi=  }}
*{{cite journal  | vauthors=Heiskala M, Peterson PA, Yang Y |title=The roles of claudin superfamily proteins in paracellular transport. |journal=Traffic |volume=2 |issue= 2 |pages= 93–8 |year= 2001 |pmid= 11247307 |doi=10.1034/j.1600-0854.2001.020203.x }}
*{{cite journal  | author=Tsukita S, Furuse M, Itoh M |title=Multifunctional strands in tight junctions. |journal=Nat. Rev. Mol. Cell Biol. |volume=2 |issue= 4 |pages= 285-93 |year= 2001 |pmid= 11283726 |doi= 10.1038/35067088 }}
*{{cite journal  | vauthors=Tsukita S, Furuse M, Itoh M |title=Multifunctional strands in tight junctions. |journal=Nat. Rev. Mol. Cell Biol. |volume=2 |issue= 4 |pages= 285–93 |year= 2001 |pmid= 11283726 |doi= 10.1038/35067088 }}
*{{cite journal  | author=Tsukita S, Furuse M |title=Claudin-based barrier in simple and stratified cellular sheets. |journal=Curr. Opin. Cell Biol. |volume=14 |issue= 5 |pages= 531-6 |year= 2003 |pmid= 12231346 |doi=  }}
*{{cite journal  | vauthors=Tsukita S, Furuse M |title=Claudin-based barrier in simple and stratified cellular sheets. |journal=Curr. Opin. Cell Biol. |volume=14 |issue= 5 |pages= 531–6 |year= 2003 |pmid= 12231346 |doi=10.1016/S0955-0674(02)00362-9 }}
*{{cite journal  | author=González-Mariscal L, Betanzos A, Nava P, Jaramillo BE |title=Tight junction proteins. |journal=Prog. Biophys. Mol. Biol. |volume=81 |issue= 1 |pages= 1-44 |year= 2003 |pmid= 12475568 |doi=  }}
*{{cite journal  | vauthors=González-Mariscal L, Betanzos A, Nava P, Jaramillo BE |title=Tight junction proteins. |journal=Prog. Biophys. Mol. Biol. |volume=81 |issue= 1 |pages= 1–44 |year= 2003 |pmid= 12475568 |doi=10.1016/S0079-6107(02)00037-8  }}
*{{cite journal  | author=Peacock RE, Keen TJ, Inglehearn CF |title=Analysis of a human gene homologous to rat ventral prostate.1 protein. |journal=Genomics |volume=46 |issue= 3 |pages= 443-9 |year= 1998 |pmid= 9441748 |doi= 10.1006/geno.1997.5033 }}
*{{cite journal  | vauthors=Yi X, Wang Y, Yu FS |title=Corneal epithelial tight junctions and their response to lipopolysaccharide challenge. |journal=Invest. Ophthalmol. Vis. Sci. |volume=41 |issue= 13 |pages= 4093–100 |year= 2000 |pmid= 11095601 |doi=  }}
*{{cite journal  | author=Yi X, Wang Y, Yu FS |title=Corneal epithelial tight junctions and their response to lipopolysaccharide challenge. |journal=Invest. Ophthalmol. Vis. Sci. |volume=41 |issue= 13 |pages= 4093-100 |year= 2000 |pmid= 11095601 |doi=  }}
*{{cite journal  | vauthors=Kiuchi-Saishin Y, Gotoh S, Furuse M |title=Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments. |journal=J. Am. Soc. Nephrol. |volume=13 |issue= 4 |pages= 875–86 |year= 2002 |pmid= 11912246 |doi=  |display-authors=etal}}
*{{cite journal  | author=Kiuchi-Saishin Y, Gotoh S, Furuse M, ''et al.'' |title=Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments. |journal=J. Am. Soc. Nephrol. |volume=13 |issue= 4 |pages= 875-86 |year= 2002 |pmid= 11912246 |doi=  }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Katoh M, Katoh M |title=CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family. |journal=Int. J. Mol. Med. |volume=11 |issue= 6 |pages= 683–9 |year= 2004 |pmid= 12736707 |doi=  10.3892/ijmm.11.6.683}}
*{{cite journal  | author=Katoh M, Katoh M |title=CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family. |journal=Int. J. Mol. Med. |volume=11 |issue= 6 |pages= 683-9 |year= 2004 |pmid= 12736707 |doi=  }}
*{{cite journal  | vauthors=Ban Y, Dota A, Cooper LJ |title=Tight junction-related protein expression and distribution in human corneal epithelium. |journal=Exp. Eye Res. |volume=76 |issue= 6 |pages= 663–9 |year= 2003 |pmid= 12742348 |doi=10.1016/S0014-4835(03)00054-X |display-authors=etal}}
*{{cite journal  | author=Ban Y, Dota A, Cooper LJ, ''et al.'' |title=Tight junction-related protein expression and distribution in human corneal epithelium. |journal=Exp. Eye Res. |volume=76 |issue= 6 |pages= 663-9 |year= 2003 |pmid= 12742348 |doi=  }}
*{{cite journal  | vauthors=Kitajiri SI, Furuse M, Morita K |title=Expression patterns of claudins, tight junction adhesion molecules, in the inner ear. |journal=Hear. Res. |volume=187 |issue= 1-2 |pages= 25–34 |year= 2004 |pmid= 14698084 |doi=10.1016/S0378-5955(03)00338-1 |display-authors=etal}}
*{{cite journal  | author=Kitajiri SI, Furuse M, Morita K, ''et al.'' |title=Expression patterns of claudins, tight junction adhesion molecules, in the inner ear. |journal=Hear. Res. |volume=187 |issue= 1-2 |pages= 25-34 |year= 2004 |pmid= 14698084 |doi=  }}
*{{cite journal  | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | vauthors=Zheng A, Yuan F, Li Y |title=Claudin-6 and claudin-9 function as additional coreceptors for hepatitis C virus. |journal=J. Virol. |volume=81 |issue= 22 |pages= 12465–71 |year= 2007 |pmid= 17804490 |doi= 10.1128/JVI.01457-07 | pmc=2169001 |display-authors=etal}}
*{{cite journal  | author=Zheng A, Yuan F, Li Y, ''et al.'' |title=Claudin-6 and claudin-9 function as additional coreceptors for hepatitis C virus. |journal=J. Virol. |volume=81 |issue= 22 |pages= 12465-71 |year= 2007 |pmid= 17804490 |doi= 10.1128/JVI.01457-07 }}
}}
}}
* {{cite journal | vauthors = Liu F, Koval M, Ranganathan S, Fanayan S, Hancock WS, Lundberg EK, Beavis RC, Lane L, Duek P, McQuade L, Kelleher NL, Baker MS | title = A systems proteomics view of the endogenous human claudin protein family | journal = J Proteome Res | date= 2015 | pmid = 26680015 | doi = 10.1021/acs.jproteome.5b00769 | url = https://archive-ouverte.unige.ch/unige:79118/ATTACHMENT01 }}
{{refend}}
{{refend}}


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Latest revision as of 09:20, 10 January 2019

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Claudin-9 is a protein that in humans is encoded by the CLDN9 gene.[1][2][3] It belongs to the group of claudins.

This gene is involved in hearing.[4]


References

  1. Peacock RE, Keen TJ, Inglehearn CF (Mar 1998). "Analysis of a human gene homologous to rat ventral prostate.1 protein". Genomics. 46 (3): 443–9. doi:10.1006/geno.1997.5033. PMID 9441748.
  2. Meertens L, Bertaux C, Cukierman L, Cormier E, Lavillette D, Cosset FL, Dragic T (Mar 2008). "The tight junction proteins claudin-1, -6, and -9 are entry cofactors for hepatitis C virus". J Virol. 82 (7): 3555–60. doi:10.1128/JVI.01977-07. PMC 2268462. PMID 18234789.
  3. "Entrez Gene: CLDN9 claudin 9".
  4. Gene discovery reveals a critical protein's function in hearing

External links

Further reading