CHMP4B: Difference between revisions

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{{Infobox_gene}}
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'''Charged multivesicular body protein 4b''' is a [[protein]] that in humans is encoded by the ''CHMP4B'' [[gene]].<ref name="pmid14678797">{{cite journal | vauthors = Katoh K, Shibata H, Hatta K, Maki M | title = CHMP4b is a major binding partner of the ALG-2-interacting protein Alix among the three CHMP4 isoforms | journal = Arch Biochem Biophys | volume = 421 | issue = 1 | pages = 159–65 |date=Dec 2003 | pmid = 14678797 | pmc =  | doi =10.1016/j.abb.2003.09.038 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CHMP4B chromatin modifying protein 4B| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=128866| accessdate = }}</ref>
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Chromatin modifying protein 4B
| HGNCid = 16171
| Symbol = CHMP4B
| AltSymbols =; CHMP4A; C20orf178; SNF7-2; Shax1; dJ553F4.4
| OMIM =
| ECnumber =
| Homologene = 57102
| MGIid = 1922858
  | GeneAtlas_image1 = PBB_GE_CHMP4B_gnf1h08576_at_tn.png
  | Function =
| Component =
| Process = {{GNF_GO|id=GO:0015031 |text = protein transport}}  
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 128866
    | Hs_Ensembl = ENSG00000101421
    | Hs_RefseqProtein = NP_789782
    | Hs_RefseqmRNA = NM_176812
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 20
    | Hs_GenLoc_start = 31862780
    | Hs_GenLoc_end = 31905830
    | Hs_Uniprot = P59074
    | Mm_EntrezGene = 75608
    | Mm_Ensembl = ENSMUSG00000038467
    | Mm_RefseqmRNA = XM_976588
    | Mm_RefseqProtein = XP_981682
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 2
    | Mm_GenLoc_start = 154348565
    | Mm_GenLoc_end = 154386226
    | Mm_Uniprot = Q9D8B3
  }}
}}
'''Chromatin modifying protein 4B''', also known as '''CHMP4B''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CHMP4B chromatin modifying protein 4B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=128866| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==External links==
* {{UCSC gene info|CHMP4A}}
* {{UCSC gene info|CHMP4B}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Deloukas P, Matthews LH, Ashurst J, ''et al.'' |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865-71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a }}
*{{cite journal  | author=Deloukas P |title=The DNA sequence and comparative analysis of human chromosome 20 |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a |name-list-format=vanc| author2=Matthews LH  | author3=Ashurst J  | display-authors=3  | last4=Burton  | first4=J.  | last5=Gilbert  | first5=J. G. R.  | last6=Jones  | first6=M.  | last7=Stavrides  | first7=G.  | last8=Almeida  | first8=J. P.  | last9=Babbage  | first9=A. K. }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Katoh K, Shibata H, Suzuki H, ''et al.'' |title=The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting. |journal=J. Biol. Chem. |volume=278 |issue= 40 |pages= 39104-13 |year= 2003 |pmid= 12860994 |doi= 10.1074/jbc.M301604200 }}
*{{cite journal  | author=Katoh K |title=The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting |journal=J. Biol. Chem. |volume=278 |issue= 40 |pages= 39104–13 |year= 2003 |pmid= 12860994 |doi= 10.1074/jbc.M301604200 |name-list-format=vanc| author2=Shibata H  | author3=Suzuki H  | display-authors=3  | last4=Nara  | first4=A  | last5=Ishidoh  | first5=K  | last6=Kominami  | first6=E  | last7=Yoshimori  | first7=T  | last8=Maki  | first8=M }}
*{{cite journal  | author=Strack B, Calistri A, Craig S, ''et al.'' |title=AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding. |journal=Cell |volume=114 |issue= 6 |pages= 689-99 |year= 2003 |pmid= 14505569 |doi=  }}
*{{cite journal  | author=Strack B |title=AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding |journal=Cell |volume=114 |issue= 6 |pages= 689–99 |year= 2003 |pmid= 14505569 |doi=10.1016/S0092-8674(03)00653-6  |name-list-format=vanc| author2=Calistri A  | author3=Craig S  | display-authors=3  | last4=Popova  | first4=Elena  | last5=Göttlinger  | first5=Heinrich G }}
*{{cite journal  | author=von Schwedler UK, Stuchell M, Müller B, ''et al.'' |title=The protein network of HIV budding. |journal=Cell |volume=114 |issue= 6 |pages= 701-13 |year= 2003 |pmid= 14505570 |doi=  }}
*{{cite journal  | author=von Schwedler UK |title=The protein network of HIV budding |journal=Cell |volume=114 |issue= 6 |pages= 701–13 |year= 2003 |pmid= 14505570 |doi=10.1016/S0092-8674(03)00714-1  |name-list-format=vanc| author2=Stuchell M  | author3=Müller B  | display-authors=3  | last4=Ward  | first4=Diane M.  | last5=Chung  | first5=Hyo-Young  | last6=Morita  | first6=Eiji  | last7=Wang  | first7=Hubert E.  | last8=Davis  | first8=Thaylon  | last9=He  | first9=Gong-Ping }}
*{{cite journal  | author=Martin-Serrano J, Yarovoy A, Perez-Caballero D, ''et al.'' |title=Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 21 |pages= 12414-9 |year= 2003 |pmid= 14519844 |doi= 10.1073/pnas.2133846100 }}
*{{cite journal  | author=Martin-Serrano J |title=Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 21 |pages= 12414–9 |year= 2003 |pmid= 14519844 |doi= 10.1073/pnas.2133846100 | pmc=218772  |name-list-format=vanc| author2=Yarovoy A  | author3=Perez-Caballero D  | display-authors=3  | last4=Bieniasz  | first4=PD }}
*{{cite journal  | author=Peck JW, Bowden ET, Burbelo PD |title=Structure and function of human Vps20 and Snf7 proteins. |journal=Biochem. J. |volume=377 |issue= Pt 3 |pages= 693-700 |year= 2004 |pmid= 14583093 |doi= 10.1042/BJ20031347 }}
*{{cite journal  | vauthors=Peck JW, Bowden ET, Burbelo PD |title=Structure and function of human Vps20 and Snf7 proteins |journal=Biochem. J. |volume=377 |issue= Pt 3 |pages= 693–700 |year= 2004 |pmid= 14583093 |doi= 10.1042/BJ20031347  | pmc=1223912 }}
*{{cite journal | author=Katoh K, Shibata H, Hatta K, Maki M |title=CHMP4b is a major binding partner of the ALG-2-interacting protein Alix among the three CHMP4 isoforms. |journal=Arch. Biochem. Biophys. |volume=421 |issue= 1 |pages= 159-65 |year= 2004 |pmid= 14678797 |doi= }}
*{{cite journal  | author=Sharma M |title=Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes |journal=J. Cell Biol. |volume=164 |issue= 6 |pages= 923–33 |year= 2004 |pmid= 15007060 |doi= 10.1083/jcb.200312018 | pmc=2172283  |name-list-format=vanc| author2=Pampinella F  | author3=Nemes C  | display-authors=3  | last4=Benharouga  | first4=M  | last5=So  | first5=J  | last6=Du  | first6=K  | last7=Bache  | first7=KG  | last8=Papsin  | first8=B  | last9=Zerangue  | first9=N }}
*{{cite journal  | author=Sharma M, Pampinella F, Nemes C, ''et al.'' |title=Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes. |journal=J. Cell Biol. |volume=164 |issue= 6 |pages= 923-33 |year= 2004 |pmid= 15007060 |doi= 10.1083/jcb.200312018 }}
*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Yorikawa C |title=Human CHMP6, a myristoylated ESCRT-III protein, interacts directly with an ESCRT-II component EAP20 and regulates endosomal cargo sorting |journal=Biochem. J. |volume=387 |issue= Pt 1 |pages= 17–26 |year= 2005 |pmid= 15511219 |doi= 10.1042/BJ20041227 | pmc=1134928  |name-list-format=vanc| author2=Shibata H  | author3=Waguri S  | display-authors=3  | last4=Hatta  | first4=Kazumi  | last5=Horii  | first5=Mio  | last6=Katoh  | first6=Keiichi  | last7=Kobayashi  | first7=Toshihide  | last8=Uchiyama  | first8=Yasuo  | last9=Maki  | first9=Masatoshi }}
*{{cite journal  | author=Yorikawa C, Shibata H, Waguri S, ''et al.'' |title=Human CHMP6, a myristoylated ESCRT-III protein, interacts directly with an ESCRT-II component EAP20 and regulates endosomal cargo sorting. |journal=Biochem. J. |volume=387 |issue= Pt 1 |pages= 17-26 |year= 2005 |pmid= 15511219 |doi= 10.1042/BJ20041227 }}
*{{cite journal  | author=Rual JF |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |name-list-format=vanc| author2=Venkatesan K  | author3=Hao T  | display-authors=3  | last4=Hirozane-Kishikawa  | first4=Tomoko  | last5=Dricot  | first5=Amélie  | last6=Li  | first6=Ning  | last7=Berriz  | first7=Gabriel F.  | last8=Gibbons  | first8=Francis D.  | last9=Dreze  | first9=Matija }}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal  | author=Tsang HT |title=A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex |journal=Genomics |volume=88 |issue= 3 |pages= 333–46 |year= 2006 |pmid= 16730941 |doi= 10.1016/j.ygeno.2006.04.003 |name-list-format=vanc| author2=Connell JW  | author3=Brown SE  | display-authors=3  | last4=Thompson  | first4=Amanda  | last5=Reid  | first5=Evan  | last6=Sanderson  | first6=Christopher M. }}
*{{cite journal  | author=Tsang HT, Connell JW, Brown SE, ''et al.'' |title=A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex. |journal=Genomics |volume=88 |issue= 3 |pages= 333-46 |year= 2006 |pmid= 16730941 |doi= 10.1016/j.ygeno.2006.04.003 }}
*{{cite journal  | vauthors=Usami Y, Popov S, Göttlinger HG |title=Potent Rescue of Human Immunodeficiency Virus Type 1 Late Domain Mutants by ALIX/AIP1 Depends on Its CHMP4 Binding Site |journal=J. Virol. |volume=81 |issue= 12 |pages= 6614–22 |year= 2007 |pmid= 17428861 |doi= 10.1128/JVI.00314-07 | pmc=1900090 }}
*{{cite journal  | author=Usami Y, Popov S, Göttlinger HG |title=Potent rescue of human immunodeficiency virus type 1 late domain mutants by ALIX/AIP1 depends on its CHMP4 binding site. |journal=J. Virol. |volume=81 |issue= 12 |pages= 6614-22 |year= 2007 |pmid= 17428861 |doi= 10.1128/JVI.00314-07 }}
*{{cite journal  | author=Shiels A |title=CHMP4B, a Novel Gene for Autosomal Dominant Cataracts Linked to Chromosome 20q |journal=Am. J. Hum. Genet. |volume=81 |issue= 3 |pages= 596–606 |year= 2007 |pmid= 17701905 |doi= 10.1086/519980 | pmc=1950844  |name-list-format=vanc| author2=Bennett TM  | author3=Knopf HL  | display-authors=3  | last4=Yamada  | first4=Koki  | last5=Yoshiura  | first5=Koh-Ichiro  | last6=Niikawa  | first6=Norio  | last7=Shim  | first7=Soomin  | last8=Hanson  | first8=Phyllis I. }}
*{{cite journal  | author=Shiels A, Bennett TM, Knopf HL, ''et al.'' |title=CHMP4B, a novel gene for autosomal dominant cataracts linked to chromosome 20q. |journal=Am. J. Hum. Genet. |volume=81 |issue= 3 |pages= 596-606 |year= 2007 |pmid= 17701905 |doi= 10.1086/519980 }}
}}
}}
{{refend}}
{{refend}}


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{{gene-20-stub}}

Latest revision as of 07:18, 10 January 2019

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Charged multivesicular body protein 4b is a protein that in humans is encoded by the CHMP4B gene.[1][2]


References

  1. Katoh K, Shibata H, Hatta K, Maki M (Dec 2003). "CHMP4b is a major binding partner of the ALG-2-interacting protein Alix among the three CHMP4 isoforms". Arch Biochem Biophys. 421 (1): 159–65. doi:10.1016/j.abb.2003.09.038. PMID 14678797.
  2. "Entrez Gene: CHMP4B chromatin modifying protein 4B".

External links

Further reading