Bubonic plague medical therapy: Difference between revisions

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{{CMG}}
#Redirect [[Yersinia pestis infection medical therapy]]
{{Bubonic plague}}
 
==Overview==
 
==Treatments==
Vladimir Havkin, an Indian doctor of Russian-Jewish origin, was the first to invent and test a plague antibiotic.
The traditional treatments are:
*[[Streptomycin]] 30 mg/kg [[intramuscular|IM]] twice daily for 7 days
*[[Chloramphenicol]] 25–30 mg/kg single dose, followed by 12.5–15 mg/kg four times daily
*[[Tetracycline]] 2 g single dose, followed by 500 mg four times daily for 7–10 days (not suitable for children)
More recently,
*[[Gentamicin]] 2.5 mg/kg [[intravenous|IV]] or [[intramuscular|IM]] twice daily for 7 days
*[[Doxycycline]] 100 mg (adults) or 2.2 mg/kg (children) orally twice daily have also been shown to be effective.<ref name="Mwengee2006">{{cite journal
| author=Mwengee W ''et al.''
| title=Treatment of Plague with Genamicin or Doxycycline in a Randomized Clinical Trial in Tanzania
| year=2006
| journal=Clin Infect Dis
| volume=42
| issue=5
| pages=614&ndash;21 }}</ref>
 
==References==
{{Reflist|2}}

Latest revision as of 02:31, 26 July 2014