Bronchitis laboratory tests: Difference between revisions

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'''Bronchitis''' is an [[inflammation]] of the [[bronchus|bronchi]] (medium-size airways) in the [[lung]]s. ''[[Acute bronchitis]]'' is usually caused by [[virus]]es or [[bacteria]] and may present as cough with sputum that last several days or weeks (10 days). Other symptoms like shortness of breath, chest discomfort, and sore throat can also be found. '''Chronic bronchitis''' is not necessarily caused by infection and is generally part of a syndrome called [[chronic obstructive pulmonary disease]] (COPD); it is defined clinically as a persistent [[cough]] that produces [[sputum]] (phlegm) and mucus, for at least three months in two consecutive years. In late stages, the disease may present with blue discoloration of body ([[cyanosis]]) and difficulty in breathing ([[dyspnea]]).
'''Bronchitis''' is an [[inflammation]] of the [[bronchus|bronchi]] (medium-size airways) in the [[lung]]s. ''[[Acute bronchitis]]'' is usually caused by [[virus]]es or [[bacteria]] and may present as cough with sputum that last several days or weeks (10 days). Other symptoms like shortness of breath, chest discomfort, and sore throat can also be found. '''Chronic bronchitis''' is not necessarily caused by infection and is generally part of a syndrome called [[chronic obstructive pulmonary disease]] (COPD); it is defined clinically as a persistent [[cough]] that produces [[sputum]] (phlegm) and mucus, for at least three months in two consecutive years. In late stages, the disease may present with blue discoloration of body ([[cyanosis]]) and difficulty in breathing ([[dyspnea]]).


==Physical examination==
==Antigen testing and Serological markers==
A variety of tests may be performed in patients presenting with cough and shortness of breath:
Rapid antigen and serological tests have limited availability and are costly. However, it can be used to as an adjunct to diagnosis in certain conditions like:
* The suspected organism is treatable
* A epidemic with the pathogen is suspected (influenza).
* Patient has typical presentation suggestive of pathogen. the infection is known to be circulating in the community, and the patient has suggestive symptoms or signs (e.g., testing for influenza during influenza season in patients with cough and fever)
Other tests
* A sputum sample showing [[neutrophil granulocyte]]s (inflammatory white blood cells) and [[microbiological culture|culture]]
* A [[blood test]] would indicate inflammation (as indicated by a raised [[white blood cell]] count and elevated [[C-reactive protein]]).
* Damage caused by irritation of the airways leads to inflammation and leads to neutrophils being present
* A [[chest X-ray]] that reveals hyperinflation; collapse and consolidation of lung areas would support a diagnosis of [[pneumonia]]. Some conditions that predispose to bronchitis may be indicated by chest radiography.
* A [[chest X-ray]] that reveals hyperinflation; collapse and consolidation of lung areas would support a diagnosis of [[pneumonia]]. Some conditions that predispose to bronchitis may be indicated by chest radiography.
* A sputum sample showing [[neutrophil granulocyte]]s (inflammatory white blood cells) and [[microbiological culture|culture]] showing that has pathogenic microorganisms such as [[Streptococcus|Streptococcus spp.]]
 
* A [[blood test]] would indicate inflammation (as indicated by a raised [[white blood cell]] count and elevated [[C-reactive protein]]).
*Neutrophils infiltrate the lung tissue, aided by damage to the airways caused by irritation.
*Damage caused by irritation of the airways leads to inflammation and leads to neutrophils being present
*Mucosal hypersecretion is promoted by a substance released by neutrophils
*Further obstruction to the airways is caused by more goblet cells in the small airways. This is typical of chronic bronchitis
*Although infection is not the reason or cause of chronic bronchitis it is seen to aid in sustaining the bronchitis.'''''
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Revision as of 18:13, 28 February 2012

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Bronchitis Main page

Patient Information

Overview

Causes

Classification

Acute bronchitis
Chronic bronchitis

Differential Diagnosis

Overview

Bronchitis is an inflammation of the bronchi (medium-size airways) in the lungs. Acute bronchitis is usually caused by viruses or bacteria and may present as cough with sputum that last several days or weeks (10 days). Other symptoms like shortness of breath, chest discomfort, and sore throat can also be found. Chronic bronchitis is not necessarily caused by infection and is generally part of a syndrome called chronic obstructive pulmonary disease (COPD); it is defined clinically as a persistent cough that produces sputum (phlegm) and mucus, for at least three months in two consecutive years. In late stages, the disease may present with blue discoloration of body (cyanosis) and difficulty in breathing (dyspnea).

Antigen testing and Serological markers

Rapid antigen and serological tests have limited availability and are costly. However, it can be used to as an adjunct to diagnosis in certain conditions like:

  • The suspected organism is treatable
  • A epidemic with the pathogen is suspected (influenza).
  • Patient has typical presentation suggestive of pathogen. the infection is known to be circulating in the community, and the patient has suggestive symptoms or signs (e.g., testing for influenza during influenza season in patients with cough and fever)

Other tests

  • A sputum sample showing neutrophil granulocytes (inflammatory white blood cells) and culture
  • A blood test would indicate inflammation (as indicated by a raised white blood cell count and elevated C-reactive protein).
  • Damage caused by irritation of the airways leads to inflammation and leads to neutrophils being present
  • A chest X-ray that reveals hyperinflation; collapse and consolidation of lung areas would support a diagnosis of pneumonia. Some conditions that predispose to bronchitis may be indicated by chest radiography.

References