Bromodiphenhydramine

Bromodiphenhydramine
Clinical data
Routes of; administration	Oral
ATC code	R06AA01 (WHO) ;
Pharmacokinetic data
Bioavailability	High
Protein binding	96%
Metabolism	Mostly hepatic (CYP-mediated), also renal
Elimination half-life	1 to 4 hours
Identifiers
	IUPAC name 2-[(4-bromophenyl)-phenylmethoxy]-N,N-dimethylethanamine;
CAS Number	118-23-0 1808-12-4 (hydrochloride);
PubChem CID	2444;
DrugBank	APRD00710;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C17H20BrNO
Molar mass	334.251 g/mol
3D model (JSmol)	Interactive image;
	SMILES CN(C)CCOC(c1ccccc1)c1ccc(Br)cc1;

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Bromazine (INN, also known as bromodiphenhydramine) is an antihistamine. It is a brominated derivative of diphenhydramine. The medicinal preparation of the hydrochloride has the brand name Ambrodyl

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v t e Antihistamines (R06)
Aminoalkyl ethers	Bromazine/Bromodiphenhydramine • Carbinoxamine • Clemastine • Chlorphenoxamine • Diphenylpyraline • Diphenhydramine • Doxylamine • Orphenadrine • Phenyltoloxamine
Substituted alkylamines	Brompheniramine • Chlorphenamine • Dexbrompheniramine • Dexchlorpheniramine • Dimetindene • Pheniramine • Talastine
Substituted ethylenediamines	Chloropyramine • Histapyrrodine • Mepyramine • Methapyrilene • Tripelennamine (Pyribenzamine)
Phenothiazine derivatives	Alimemazine • Hydroxyethylpromethazine • Isothipendyl • Mequitazine • Methdilazine • Oxomemazine • Promethazine
Piperazine derivatives	Buclizine • Cetirizine • Chlorcyclizine • Cinnarizine • Cyclizine • Hydroxyzine • Levocetirizine • Meclizine • Niaprazine • Oxatomide
Others for systemic use	Antazoline • Azatadine • Bamipine • Cyproheptadine • Deptropine • Dimebon • Ebastine • Epinastine • Ketotifen • Mebhydrolin • Mizolastine • Phenindamine • Pimethixene • Pyrrobutamine • Rupatadine • Triprolidine • selective (Acrivastine • Astemizole • Azelastine • Desloratadine • Fexofenadine • Loratadine • Terfenadine)
For topical use	Bamipine • Chloropyramine • Chlorphenoxamine • Clemastine • Dimetindene • Diphenhydramine • Isothipendyl • Mepyramine • Promethazine • Thenalidine
Antiallergic agents excluding corticosteroids	Antazoline • Azelastine
Other antiallergics	Emedastine • Epinastine • Ketotifen • Montelukast • Olopatadine

Clinical data
Routes of administration	Oral
ATC code	R06AA01 (WHO)
Pharmacokinetic data
Bioavailability	High
Protein binding	96%
Metabolism	Mostly hepatic (CYP-mediated), also renal
Elimination half-life	1 to 4 hours
Identifiers
IUPAC name 2-[(4-bromophenyl)-phenylmethoxy]-N,N-dimethylethanamine
CAS Number	118-23-0 1808-12-4 (hydrochloride)
PubChem CID	2444
DrugBank	APRD00710
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₇H₂₀BrNO
Molar mass	334.251 g/mol
3D model (JSmol)	Interactive image
SMILES CN(C)CCOC(c1ccccc1)c1ccc(Br)cc1

Bromodiphenhydramine

Overview

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