Brain tumor staging: Difference between revisions

	Brain tumor Microchapters
Patient Information
Overview
Classification Adult brain tumors Glioblastoma multiforme Oligodendroglioma Meningioma Hemangioblastoma Pituitary adenoma Schwannoma Primary CNS lymphoma Childhood brain tumors Pilocytic astrocytoma Medulloblastoma Ependymoma Craniopharyngioma Pinealoma Metastasis Lung cancer Breast cancer Melanoma Gastrointestinal tract cancer Renal cell carcinoma Osteoblastoma Head and neck cancer Neuroblastoma Lymphoma Prostate cancer
Causes
Differentiating Brain Tumor from other Diseases

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Latest revision as of 20:41, 29 July 2020

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

The subtypes of brain tumors have different staging systems based on the grade, extent of spread, size and presence of distant metastases. According to WHO histologic grading for brain tumors, the grades of brain tumors are subdivided into Grades 1,2,3 and 4. The lower the grade, better the prognosis.

WHO Histologic Grading for CNS Tumors

According to WHO histologic grading for brain tumors, the grades of brain tumors are subdivided into Grades 1,2,3 and 4.^[1]

Grade I

Lesions with low proliferative potential, a frequently discrete nature, and the possibility of cure following surgical resection alone
- Juvenile pilocytic astrocytoma
- Subependymal giant cell astrocytoma

Grade II

Lesions that are generally infiltrating and low in mitotic activity but recur; some tumor types tend to progress to higher grades of malignancy
- Pilomyxoid astrocytoma
- Pleomorphic xanthoastrocytoma
- Diffuse astrocytoma
- Fibrillary astrocytoma
- Protoplasmic astrocytoma
- Gemistocytic astrocytoma

Grade III

Lesions with histologic evidence of malignancy, generally in the form of mitotic activity, clearly expressed infiltrative capabilities, and anaplasia
- Anaplastic astrocytoma

Grade IV

Lesions that are mitotically active, necrosis-prone, and generally associated with a rapid preoperative and postoperative evolution of disease
- Glioblastoma
- Giant cell glioblastoma
- Gliosarcoma
- Gliomatosis cerebri^[1]

References

↑ ^1.0 ^1.1 Grading of brain tumors.Dr Amir Rezaee and Dr Frank Gaillard et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/cns-tumours-classification-and-grading-who

Template:WH Template:WS

[radiology-1] 1.0 ^1.1 Grading of brain tumors.Dr Amir Rezaee and Dr Frank Gaillard et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/cns-tumours-classification-and-grading-who

[1]

@@ Line 1: / Line 1: @@
-Staging is a way of describing a tumor, such as where it is located, if or where it has spread, and whether it is affecting the functions of other organs in the body. A staging system is used for most other types of cancer. There is a formal staging system for adult brain tumors; however, the grading system described below is always used instead.
+__NOTOC__
+{{Brain tumor}}
+{{CMG}}{{AE}}{{SR}}
+==Overview==
+The subtypes of brain tumors have different staging systems based on the grade, extent of spread, size and presence of distant metastases. According to WHO histologic grading for brain tumors, the grades of brain tumors are subdivided into Grades 1,2,3 and 4. The lower the grade, better the prognosis.
-After a brain tumor has been diagnosed, additional tests will be done to learn more about the tumor. If the tumor is a glial brain tumor, the pathologist will assign a “grade” using a number from I to IV (one to four). The grade indicates how different the tumor cells are from healthy cells, with a higher grade tumor having cells that are the least like healthy cells. The characteristics of the tumor, as seen under the microscope, help determine how cancerous a tumor is. Generally, the lower the grade, the better the prognosis (chance of recovery or long-term control of the tumor).
+==WHO Histologic Grading for CNS Tumors==
+According to WHO histologic grading for brain tumors, the grades of brain tumors are subdivided into Grades 1,2,3 and 4.<ref name=radiology>Grading of brain tumors.Dr Amir Rezaee and Dr Frank Gaillard et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/cns-tumours-classification-and-grading-who</ref>
+===Grade I===
-'''WHO histologic grading for CNS tumors:'''
-''Grade I:''
 * Lesions with low proliferative potential, a frequently discrete nature, and the possibility of cure following surgical resection alone
-* Juvenile pilocytic astrocytoma, subependymal giant cell astrocytoma
+**Juvenile pilocytic astrocytoma
+**Subependymal giant cell astrocytoma
-''Grade II:''
+===Grade II===
 * Lesions that are generally infiltrating and low in mitotic activity but recur; some tumor types tend to progress to higher grades of malignancy
-* Diffuse astrocytoma, oligodendroglioma, oligoastrocytoma
+**Pilomyxoid astrocytoma
+**Pleomorphic xanthoastrocytoma
+**Diffuse astrocytoma
+**Fibrillary astrocytoma
+**Protoplasmic astrocytoma
+**Gemistocytic astrocytoma
-''Grade III:''
+===Grade III===
 * Lesions with histologic evidence of malignancy, generally in the form of mitotic activity, clearly expressed infiltrative capabilities, and anaplasia
-* Anaplastic astrocytoma, anaplastic oligoastrocytoma, anaplastic oligoastrocytoma
+**Anaplastic astrocytoma
-''Grade IV:''
+===Grade IV===
 * Lesions that are mitotically active, necrosis-prone, and generally associated with a rapid preoperative and postoperative evolution of disease
-* Glioblastoma
+**Glioblastoma
+**Giant cell glioblastoma
+**Gliosarcoma
+**Gliomatosis cerebri<ref name=radiology>Grading of brain tumors.Dr Amir Rezaee and Dr Frank Gaillard et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/cns-tumours-classification-and-grading-who</ref>
+==References==
+{{Reflist|2}}
+{{WH}}
+{{WS}}
+[[Category:Disease]]
+[[Category:Brain]]
+[[Category:Neurology]]
+[[Category:Up-To-Date]]
+[[Category:Oncology]]
+[[Category:Medicine]]
+[[Category:Neurosurgery]]