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**Serum lactate
**Serum lactate
***Elevated serum lactate may suggest bowel ischemia
***Elevated serum lactate may suggest bowel ischemia
 
**Procalcitonin
***Prognostic biomarker, elevation more than 0.57ng/ml indicates failure of non-operative management





Revision as of 15:58, 7 February 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]

Overview

Laboratory findings consistent with the diagnosis of bowel obstruction include hyponatremia and hypokalemia, leukocytosis, metabolic alkalosis and elevated serum lactate.

Laboratory Findings

  • Laboratory findings that may be carried out in order to diagnosis bowel obstruction include:[1][2][3]
    • Complete blood count
      • To identify anemia, which may indicate a specific etiology such as Crohn's disease, Meckel's diverticulum or malignancy
      • To identify leukocytosis
    • Blood urea nitrogen
    • Creatinine
    • Eletrolytes
      • The presence of hyponatremia and hypokalemia is often noted in cases of bowel obstruction
    • Arterial blood gases
      • Although not routine, is useful to assess systemic signs such as hypotension and also for cases of metabolic alkalosis
    • Serum lactate
      • Elevated serum lactate may suggest bowel ischemia
    • Procalcitonin
      • Prognostic biomarker, elevation more than 0.57ng/ml indicates failure of non-operative management


References

  1. Takeuchi K, Tsuzuki Y, Ando T, Sekihara M, Hara T, Yoshikawa M, Kuwano H (2004). "Clinical studies of strangulating small bowel obstruction". Am Surg. 70 (1): 40–4. PMID 14964545.
  2. Murray MJ, Gonze MD, Nowak LR, Cobb CF (1994). "Serum D(-)-lactate levels as an aid to diagnosing acute intestinal ischemia". Am. J. Surg. 167 (6): 575–8. PMID 8209931.
  3. Lange H, Jäckel R (1994). "Usefulness of plasma lactate concentration in the diagnosis of acute abdominal disease". Eur J Surg. 160 (6–7): 381–4. PMID 7948358.


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