Bleeding Academic Research Consortium

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=='Bleeding Academic Research Consortium (BARC)' definition for Bleeding (DONOT EDIT)[1]

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  • ===Type 0===: no bleeding
  • ===Type 1===: bleeding that is not actionable and does not cause the patient to seek unscheduled performance of studies, hospitalization, or treatment by a health-care professional; may include episodes leading to self-discontinuation of medical therapy by the patient without consulting a health-care professional.
  • ===Type 2===: any overt, actionable sign of hemorrhage (eg, more bleeding than would be expected for a clinical circumstance, including bleeding found by imaging alone) that does not fit the criteria for type 3, 4, or 5 but does meet at least one of the following criteria: (1) requiring nonsurgical, medical intervention by a health-care professional, (2) leading to hospitalization or increased level of care, or (3) prompting evaluation
  • ===Type 3===
    • ====Type 3a====: Overt bleeding plus hemoglobin drop of 3 to < 5 g/dL* (provided hemoglobin drop is related to bleed)Any transfusion with overt bleeding
    • ====Type 3b====: Overt bleeding plus hemoglobin drop more than or equal to 5 g/dL* (provided hemoglobin drop is related to bleed)Cardiac tamponade, Bleeding requiring surgical intervention for control (excludingdental/nasal/skin/hemorrhoid), Bleeding requiring intravenous vasoactive agents
    • ====Type 3c====: Intracranial hemorrhage (does not include microbleeds or hemorrhagic transformation, does include intraspinal), Subcategories confirmed by autopsy or imaging or lumbar puncture, Intraocular bleed compromising vision.
    • ====Type 4====: CABG-related bleeding, Perioperative intracranial bleeding within 48 h, Reoperation after closure of sternotomy for the purpose of controlling bleeding

Transfusion of more than equal to 5 U whole blood or packed red blood cells within a 48-h period, Chest tube output more than or equal to 2L within a 24-h period

  • ===Type 5===: fatal bleeding
    • ====Type 5a====: Probable fatal bleeding; no autopsy or imaging confirmation but clinically suspicious
    • ====Type 5b====: Definite fatal bleeding; overt bleeding or autopsy or imaging confirmation
  1. Mehran R, Rao SV, Bhatt DL, Gibson CM, Caixeta A, Eikelboom J; et al. (2011). "Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the bleeding academic research consortium". Circulation. 123 (23): 2736–47. doi:10.1161/CIRCULATIONAHA.110.009449. PMID 21670242.