Bithionol: Difference between revisions

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Bithionol
Clinical data
Synonyms	2,4-dichloro- 6-(3,5-dichloro- 2-hydroxyphenyl)sulfanylphenol
ATC code	D10AB01 (WHO) P02BX01 (WHO) Template:ATCvet;
Identifiers
	IUPAC name 2,2'-sulfanediylbis(4,6-dichlorophenol);
CAS Number	97-18-7 ;
PubChem CID	2406;
IUPHAR/BPS	2338;
DrugBank	DB04813 ;
ChemSpider	2313 ;
UNII	AMT77LS62O;
ChEBI	CHEBI:3131 ;
ChEMBL	ChEMBL290106 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C12H6Cl4O2S
Molar mass	356.05 g/mol
3D model (JSmol)	Interactive image;
	SMILES Clc2cc(Cl)cc(Sc1cc(Cl)cc(Cl)c1O)c2O;
	InChI InChI=1S/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H ; Key:JFIOVJDNOJYLKP-UHFFFAOYSA-N ;
(what is this?) (verify)

VisualWikitext

Latest revision as of 18:11, 18 August 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Bithionol is an anthelmintic used to treat Anoplocephala perfoliata (tapeworms) in horses^[1] and Fasciola hepatica (liver flukes).

References

↑ Sanada Y, Senba H, Mochizuki R, Arakaki H, Gotoh T, Fukumoto S, Nagahata H (2009). "Evaluation of Marked Rise in Fecal Egg Output after Bithionol Administration to Horse and its Application as a Diagnostic Marker for Equine Anoplocephala perfoliata Infection" (pdf). Journal of Veterinary Medical Science. 71 (5): 617–620. doi:10.1292/jvms.71.617. PMID 19498288.

Template:Anthelmintics

[1] Sanada Y, Senba H, Mochizuki R, Arakaki H, Gotoh T, Fukumoto S, Nagahata H (2009). "Evaluation of Marked Rise in Fecal Egg Output after Bithionol Administration to Horse and its Application as a Diagnostic Marker for Equine Anoplocephala perfoliata Infection" (pdf). Journal of Veterinary Medical Science. 71 (5): 617–620. doi:10.1292/jvms.71.617. PMID 19498288.

[1]

@@ Line 1: / Line 1: @@
-__NOTOC__
+{{Drugbox
-{{CMG}}
+| Verifiedfields = changed
+| Watchedfields = changed
+| verifiedrevid = 459980346
+| IUPAC_name = 2,2'-sulfanediylbis(4,6-dichlorophenol)
+| image = Bithionol.png
+| image2 = Bithionol_molecule_ball.png
+| alt2 = Ball-and-stick model of the bithionol molecule
+| width2 = 240
-==Overview==
+<!--Clinical data-->
+| tradename =
+| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
+| pregnancy_US = <!-- A / B            / C / D / X -->
+| pregnancy_category =
+| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
+| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII -->
+| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C -->
+| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
+| legal_status =
+| routes_of_administration =
-'''Bithionol''' is an [[anthelmintic]] used to treat  "[[Anoplocephala perfoliata]]" (tapeworms) in horses<ref>[http://www.ncbi.nlm.nih.gov/pubmed/19498288], Sanada Y, Senba H, Mochizuki R, et al. Evaluation of marked rise in fecal egg output after bithionol administration to horse and its application as a diagnostic marker for equine Anoplocephala perfoliata infection. J. Vet. Med. Sci. May 2009;71(5):617-620.</ref> and ''[[Fasciola hepatica]]'' (liver flukes).
+<!--Pharmacokinetic data-->
+| bioavailability =
+| protein_bound =
+| metabolism =
+| elimination_half-life =
+| excretion =
-==Category==
+<!--Identifiers-->
+| CAS_number_Ref = {{cascite|changed|??}}
+| CAS_number = 97-18-7
+| ATC_prefix = D10
+| ATC_suffix = AB01
+| ATC_supplemental =  {{ATC|P02|BX01}} {{ATCvet|P52|AG07}}
+| PubChem = 2406
+| IUPHAR_ligand = 2338
+| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
+| DrugBank = DB04813
+| UNII_Ref = {{fdacite|correct|FDA}}
+| UNII = AMT77LS62O
+| ChEMBL_Ref = {{ebicite|correct|EBI}}
+| ChEMBL = 290106
+|  ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
+| ChemSpiderID = 2313
+|  ChEBI_Ref = {{ebicite|correct|EBI}}
+| ChEBI = 3131
+| smiles = Clc2cc(Cl)cc(Sc1cc(Cl)cc(Cl)c1O)c2O
+|  InChI = 1/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H
+|  InChIKey = JFIOVJDNOJYLKP-UHFFFAOYAO
+|  StdInChI_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChI = 1S/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H
+|  StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChIKey = JFIOVJDNOJYLKP-UHFFFAOYSA-N
-Antiparasite
+<!--Chemical data-->
+| C=12 | H=6 | Cl=4 | O=2 | S=1
+| molecular_weight = 356.05 g/mol
+| synonyms = 2,4-dichloro- 6-(3,5-dichloro- 2-hydroxyphenyl)sulfanylphenol
+}}
+              __NOTOC__
+{{SI}}
+{{CMG}}
+==Overview==
+'''Bithionol''' is an [[anthelmintic]] used to treat ''[[Anoplocephala perfoliata]]'' (tapeworms) in horses<ref>{{ cite journal | author = Sanada Y, Senba H, Mochizuki R, Arakaki H, Gotoh T, Fukumoto S, Nagahata H | title = Evaluation of Marked Rise in Fecal Egg Output after Bithionol Administration to Horse and its Application as a Diagnostic Marker for Equine ''Anoplocephala perfoliata'' Infection | journal = Journal of Veterinary Medical Science | year = 2009 | volume = 71 | issue = 5 | pages = 617–620 | pmid = 19498288 | doi = 10.1292/jvms.71.617 | url = https://www.jstage.jst.go.jp/article/jvms/71/5/71_5_617/_pdf | format = pdf }}</ref> and ''[[Fasciola hepatica]]'' (liver flukes).
-==Brand Names==
+==References==
+{{reflist|2}}
-Bithionol is investigational in the U.S. The drug can be obtained from the Centers for Disease Control (CDC) Drug Service, CDC, Atlanta, Georgia 30333 (404-639-3670; evenings, weekends, or holidays: 404-639-2888).
-==Prescribing Information==
+{{Anthelmintics}}
-'''  [[XXXXX description|Description]]'''
-'''| [[XXXXX clinical pharmacology|Clinical Pharmacology]]'''
-'''| [[XXXXX microbiology|Microbiology]]'''
-'''| [[XXXXX indications and usage|Indications and Usage]]'''
-'''| [[XXXXX contraindications|Contraindications]]'''
-'''| [[XXXXX warnings and precautions|Warnings and Precautions]]'''
-'''| [[XXXXX adverse reactions|Adverse Reactions]]'''
-'''| [[XXXXX drug interactions|Drug Interactions]]'''
-'''| [[XXXXX overdosage|Overdosage]]'''
-'''| [[XXXXX clinical studies|Clinical Studies]]'''
-'''| [[XXXXX dosage and administration|Dosage and Administration]]'''
-'''| [[XXXXX how supplied|How Supplied]]'''
-'''| [[XXXXX labels and packages|Labels and Packages]]'''
-==Mechanism of Action==
-==References==
-{{Reflist|2}}
-[[Category:Antibiotics]]
+[[Category:Antiparasitic agents]]
-[[Category:Wikinfect]]
+[[Category:Organochlorides]]
+[[Category:Phenols]]
+[[Category:Thioethers]]
+[[Category:Drug]]

Bithionol: Difference between revisions

Latest revision as of 18:11, 18 August 2015

Overview

References

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