Bicuspid aortic stenosis risk factors: Difference between revisions

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(Created page with "{{Bicuspid aortic stenosis}} {{CMG}}; {{AOEIC}} {{VK}} ==Risk Factors== Factors affecting the rate of stenosis of bicuspid valves are not clearly defined. *The rate of [[cal...")
 
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**Asymmetrical leaflet sizes as there is more pronounced hemodynamic stress, resulting from straightening and stretching of the leaflets when they are open and close<ref name="pmid13725804">{{cite journal |author=EDWARDS JE |title=The congenital bicuspid aortic valve |journal=[[Circulation]] |volume=23 |issue= |pages=485–8 |year=1961 |month=April |pmid=13725804 |doi= |url=http://circ.ahajournals.org/cgi/pmidlookup?view=long&pmid=13725804 |accessdate=2012-04-10}}</ref>
**Asymmetrical leaflet sizes as there is more pronounced hemodynamic stress, resulting from straightening and stretching of the leaflets when they are open and close<ref name="pmid13725804">{{cite journal |author=EDWARDS JE |title=The congenital bicuspid aortic valve |journal=[[Circulation]] |volume=23 |issue= |pages=485–8 |year=1961 |month=April |pmid=13725804 |doi= |url=http://circ.ahajournals.org/cgi/pmidlookup?view=long&pmid=13725804 |accessdate=2012-04-10}}</ref>
*Sclerotic changes resulting in stenosis tend to occur at faster rate in patients with:<ref name="pmid8427176">{{cite journal |author=Beppu S, Suzuki S, Matsuda H, Ohmori F, Nagata S, Miyatake K |title=Rapidity of progression of aortic stenosis in patients with congenital bicuspid aortic valves |journal=[[The American Journal of Cardiology]] |volume=71 |issue=4 |pages=322–7 |year=1993 |month=February |pmid=8427176 |doi= |url= |accessdate=2012-04-10}}</ref>
*Sclerotic changes resulting in stenosis tend to occur at faster rate in patients with:<ref name="pmid8427176">{{cite journal |author=Beppu S, Suzuki S, Matsuda H, Ohmori F, Nagata S, Miyatake K |title=Rapidity of progression of aortic stenosis in patients with congenital bicuspid aortic valves |journal=[[The American Journal of Cardiology]] |volume=71 |issue=4 |pages=322–7 |year=1993 |month=February |pmid=8427176 |doi= |url= |accessdate=2012-04-10}}</ref>
**Anteroposteriorly located cusps than in those with right-left-located cusps
**Anteroposteriorly located cusps than in those with right-left located cusps
**Asymmetrical leaflet sizes
**Asymmetrical leaflet sizes


==References==
==References==

Revision as of 03:07, 11 April 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S. [2]

Risk Factors

Factors affecting the rate of stenosis of bicuspid valves are not clearly defined.

  • The rate of calcification of the bicuspid aortic valve depends on:[1]
    • Total cholesterol
    • Hypertension
    • Asymmetrical leaflet sizes as there is more pronounced hemodynamic stress, resulting from straightening and stretching of the leaflets when they are open and close[2]
  • Sclerotic changes resulting in stenosis tend to occur at faster rate in patients with:[3]
    • Anteroposteriorly located cusps than in those with right-left located cusps
    • Asymmetrical leaflet sizes

References

  1. Chan KL, Ghani M, Woodend K, Burwash IG (2001). "Case-controlled study to assess risk factors for aortic stenosis in congenitally bicuspid aortic valve". The American Journal of Cardiology. 88 (6): 690–3. PMID 11564401. Retrieved 2012-04-10. Unknown parameter |month= ignored (help)
  2. EDWARDS JE (1961). "The congenital bicuspid aortic valve". Circulation. 23: 485–8. PMID 13725804. Retrieved 2012-04-10. Unknown parameter |month= ignored (help)
  3. Beppu S, Suzuki S, Matsuda H, Ohmori F, Nagata S, Miyatake K (1993). "Rapidity of progression of aortic stenosis in patients with congenital bicuspid aortic valves". The American Journal of Cardiology. 71 (4): 322–7. PMID 8427176. Unknown parameter |month= ignored (help); |access-date= requires |url= (help)

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