Behçet's disease history and symptoms: Difference between revisions

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==Overview==
==Overview==
Behçet's disease may affect multiple organs depending upon the specific blood vessels that are affected. Common symptoms include painful [[mouth sores]], [[skin lesions]], [[uveitis]], [[joint pain]], and genital sores.
The hallmark of Behçet disease is recurrent [[Aphthous ulceration|aphthous ulcerations]], [[Genital ulcer|genital ulcers]], and [[uveitis]]. A positive history of [[joint pains]] and [[Skin lesion|skin lesions]] are suggestive of Behçet disease. The most common symptoms of Behçet disease include [[mouth sores]], [[uveitis]], [[joint pain]], and genital sores. Less common symptoms of Behçet disease include [[diarrhea]], [[abdominal pain]], [[headache]], [[Skin lesion|skin lesions]]-red nodules, [[Acne vulgaris|acne]], [[Arthritis|joint pains]], and poor balance.
 
The majority of patients with [disease name] are asymptomatic.
 
OR
 
The hallmark of [disease name] is [finding]. A positive history of joint pains and skin lesions are suggestive of Behcet disease. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].


==History and Symptoms==
==History and Symptoms==
*The hallmark of Behcet disease is recurrent aphthous ulcerations, genital ulcers, and uveitis. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
The hallmark of Behçet disease is recurrent [[Aphthous ulcer|aphthous]] ulcerations, [[Genital ulcer|genital ulcers]], and [[uveitis]]. A positive history of [[Arthritis|joint pains]] and [[Skin lesion|skin lesions]] are suggestive of Behçet disease. The most common symptoms of Behçet disease include [[mouth sores]], [[uveitis]], [[joint pain]], and [[Genital ulcer|genital sores]].<ref name="pmid3159316">{{cite journal| author=Vuitton D, Neidhardt-Audion M, Girardin P, Racadot E, Geissmann C, Laurent R et al.| title=[Epidemiologic characteristics of 21 peranesthetic anaphylactoid accidents observed in a population of 12,855 surgically treated patients]. | journal=Ann Fr Anesth Reanim | year= 1985 | volume= 4 | issue= 2 | pages= 167-72 | pmid=3159316 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3159316  }} </ref><ref name="pmid21586851">{{cite journal| author=Al-Mujaini A, Wali UK| title=Frosted branch angiitis, neuroretinitis as initial ocular manifestation in Behçet disease. | journal=Indian J Ophthalmol | year= 2011 | volume= 59 | issue= 3 | pages= 240-1 | pmid=21586851 | doi=10.4103/0301-4738.81048 | pmc=3120249 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21586851  }} </ref><ref name="pmid29026416">{{cite journal| author=Ebrahimifar P, Shahabi J| title=Right ventricular thrombosis as a manifestation of Behçet's syndrome. | journal=ARYA Atheroscler | year= 2017 | volume= 13 | issue= 2 | pages= 91-94 | pmid=29026416 | doi= | pmc=5628857 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29026416  }} </ref><ref name="pmid21869912">{{cite journal| author=Seyahi E, Yurdakul S| title=Behçet's Syndrome and Thrombosis. | journal=Mediterr J Hematol Infect Dis | year= 2011 | volume= 3 | issue= 1 | pages= e2011026 | pmid=21869912 | doi=10.4084/MJHID.2011.026 | pmc=3152448 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21869912  }} </ref>


===History===
===History===
Patients with [disease name]] may have a positive history of:
Patients with Behçet disease may have a positive history of:
*[History finding 1]
*[[Oral ulcer|Mouth sores]]
*[History finding 2]
*[[Genital ulcer|Genital sores]]
*[History finding 3]
*[[Eye pain]] and [[Edema|swelling]]<ref name="pmid3159316">{{cite journal| author=Vuitton D, Neidhardt-Audion M, Girardin P, Racadot E, Geissmann C, Laurent R et al.| title=[Epidemiologic characteristics of 21 peranesthetic anaphylactoid accidents observed in a population of 12,855 surgically treated patients]. | journal=Ann Fr Anesth Reanim | year= 1985 | volume= 4 | issue= 2 | pages= 167-72 | pmid=3159316 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3159316  }} </ref><ref name="pmid21586851">{{cite journal| author=Al-Mujaini A, Wali UK| title=Frosted branch angiitis, neuroretinitis as initial ocular manifestation in Behçet disease. | journal=Indian J Ophthalmol | year= 2011 | volume= 59 | issue= 3 | pages= 240-1 | pmid=21586851 | doi=10.4103/0301-4738.81048 | pmc=3120249 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21586851  }} </ref>
*[[Headache]]
*[[Diarrhea]]
*[[Abdominal pain]]
*[[Arthritis|Joint pains]]
*[[Skin lesion|Skin lesions]]<ref name="pmid29026416">{{cite journal| author=Ebrahimifar P, Shahabi J| title=Right ventricular thrombosis as a manifestation of Behçet's syndrome. | journal=ARYA Atheroscler | year= 2017 | volume= 13 | issue= 2 | pages= 91-94 | pmid=29026416 | doi= | pmc=5628857 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29026416  }} </ref><ref name="pmid21869912">{{cite journal| author=Seyahi E, Yurdakul S| title=Behçet's Syndrome and Thrombosis. | journal=Mediterr J Hematol Infect Dis | year= 2011 | volume= 3 | issue= 1 | pages= e2011026 | pmid=21869912 | doi=10.4084/MJHID.2011.026 | pmc=3152448 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21869912  }} </ref>


===Common Symptoms===
===Common Symptoms===
Common symptoms of [disease] include:
Common symptoms of Behçet disease include:
*[Symptom 1]
*[[Oral ulcer|Mouth sores]]
*[Symptom 2]
*[[Genital ulcer|Genital sores]]
*[Symptom 3]
*[[Eye pain]] and [[Edema|swelling]]<ref name="pmid3159316">{{cite journal| author=Vuitton D, Neidhardt-Audion M, Girardin P, Racadot E, Geissmann C, Laurent R et al.| title=[Epidemiologic characteristics of 21 peranesthetic anaphylactoid accidents observed in a population of 12,855 surgically treated patients]. | journal=Ann Fr Anesth Reanim | year= 1985 | volume= 4 | issue= 2 | pages= 167-72 | pmid=3159316 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3159316  }} </ref><ref name="pmid21586851">{{cite journal| author=Al-Mujaini A, Wali UK| title=Frosted branch angiitis, neuroretinitis as initial ocular manifestation in Behçet disease. | journal=Indian J Ophthalmol | year= 2011 | volume= 59 | issue= 3 | pages= 240-1 | pmid=21586851 | doi=10.4103/0301-4738.81048 | pmc=3120249 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21586851  }} </ref>


===Less Common Symptoms===
===Less Common Symptoms===
Less common symptoms of [disease name] include  
Less common symptoms of Behçet disease include:
*[Symptom 1]
*[[Diarrhea]]
*[Symptom 2]
*[[Abdominal pain]]
*[Symptom 3]
*[[Headache]]
 
*[[Skin lesion|Skin lesions]]-red [[Nodule (medicine)|nodules]], [[Acne vulgaris|acne]]
Signs and symptoms of Behçet's disease vary from person to person, depending on the blood vessels affected. Many patients show multiple organ damages. Like other autoimmune diseases, signs and symptoms come and go.
*[[Arthritis|Joint pains]]
:*Painful mouth sores: These are the most common sign of Behçet's disease. Mouth sores turn quickly from lesion to ulcers and heal in 7~21 days.
*Poor balance
:*Skin lesions: Skin lesions in patients with Behçet's disease vary, from acne-like sores to red tender nodules.
*[[Depression]] and [[anxiety]]<ref name="pmid26913703">{{cite journal| author=Ilhan B, Can M, Alibaz-Oner F, Yilmaz-Oner S, Polat-Korkmaz O, Ozen G et al.| title=Fatigue in patients with Behcet's syndrome: relationship with quality of life, depression, anxiety, disability and disease activity. | journal=Int J Rheum Dis | year= 2016 | volume=  | issue=  | pages=  | pmid=26913703 | doi=10.1111/1756-185X.12839 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26913703  }} </ref><ref name="pmid26487169">{{cite journal| author=Buyuktas D, Hatemi G, Yuksel-Findikoglu S, Ugurlu S, Yazici H, Yurdakul S| title=Fatigue is correlated with disease activity but not with the type of organ involvement in Behçet's syndrome: a comparative clinical survey. | journal=Clin Exp Rheumatol | year= 2015 | volume= 33 | issue= 6 Suppl 94 | pages= S107-12 | pmid=26487169 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26487169  }} </ref>
:*Brain: When Behçet's disease affect brain, it leads to [[headache]], [[fever]], [[disorientation]], poor balance, even [[stroke]].
:*Digestive system: Patients with Behçet's disease may show symptoms such as [[abdominal pain]], [[diarrhea]] or [[bleeding]].
:*Eyes: Behçet's disease may cause inflammation in the eye, such as [[uveitis]].
:*Joints: Patients with Behçet's disease may have [[joint swelling]] and [[joint pain]] when joints are affected with inflammation.
:*Vascular system: Inflammation may occur on veins and large arteries, leading redness, pain and swelling in the arms or legs, even [[aneurysm]]s and narrowing or blockage of the vessel.
:*Genitals: Patients with Behçet's disease may develop sores on their genitals, feeling [[pain]] and leaving scars.
 
==Less Common Symptoms==


==References==
==References==
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Latest revision as of 20:36, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]

Overview

The hallmark of Behçet disease is recurrent aphthous ulcerations, genital ulcers, and uveitis. A positive history of joint pains and skin lesions are suggestive of Behçet disease. The most common symptoms of Behçet disease include mouth sores, uveitis, joint pain, and genital sores. Less common symptoms of Behçet disease include diarrhea, abdominal pain, headache, skin lesions-red nodules, acne, joint pains, and poor balance.

History and Symptoms

The hallmark of Behçet disease is recurrent aphthous ulcerations, genital ulcers, and uveitis. A positive history of joint pains and skin lesions are suggestive of Behçet disease. The most common symptoms of Behçet disease include mouth sores, uveitis, joint pain, and genital sores.[1][2][3][4]

History

Patients with Behçet disease may have a positive history of:

Common Symptoms

Common symptoms of Behçet disease include:

Less Common Symptoms

Less common symptoms of Behçet disease include:

References

  1. 1.0 1.1 1.2 Vuitton D, Neidhardt-Audion M, Girardin P, Racadot E, Geissmann C, Laurent R; et al. (1985). "[Epidemiologic characteristics of 21 peranesthetic anaphylactoid accidents observed in a population of 12,855 surgically treated patients]". Ann Fr Anesth Reanim. 4 (2): 167–72. PMID 3159316.
  2. 2.0 2.1 2.2 Al-Mujaini A, Wali UK (2011). "Frosted branch angiitis, neuroretinitis as initial ocular manifestation in Behçet disease". Indian J Ophthalmol. 59 (3): 240–1. doi:10.4103/0301-4738.81048. PMC 3120249. PMID 21586851.
  3. 3.0 3.1 Ebrahimifar P, Shahabi J (2017). "Right ventricular thrombosis as a manifestation of Behçet's syndrome". ARYA Atheroscler. 13 (2): 91–94. PMC 5628857. PMID 29026416.
  4. 4.0 4.1 Seyahi E, Yurdakul S (2011). "Behçet's Syndrome and Thrombosis". Mediterr J Hematol Infect Dis. 3 (1): e2011026. doi:10.4084/MJHID.2011.026. PMC 3152448. PMID 21869912.
  5. Ilhan B, Can M, Alibaz-Oner F, Yilmaz-Oner S, Polat-Korkmaz O, Ozen G; et al. (2016). "Fatigue in patients with Behcet's syndrome: relationship with quality of life, depression, anxiety, disability and disease activity". Int J Rheum Dis. doi:10.1111/1756-185X.12839. PMID 26913703.
  6. Buyuktas D, Hatemi G, Yuksel-Findikoglu S, Ugurlu S, Yazici H, Yurdakul S (2015). "Fatigue is correlated with disease activity but not with the type of organ involvement in Behçet's syndrome: a comparative clinical survey". Clin Exp Rheumatol. 33 (6 Suppl 94): S107–12. PMID 26487169.

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