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{{Basal cell carcinoma}}
{{Basal cell carcinoma}}
{{CMG}} {{AE}} Saarah T. Alkhairy, M.D.
{{CMG}} {{AE}} Saarah T. Alkhairy, M.D.,{{M.N}}


==Overview==
==Overview==
Types of surgery for basal cell carcinoma involve electrodesiccation and curettage, surgical excision, mohs micrographic surgery, and cryosurgery.
Types of [[surgery]] for basal cell carcinoma involve electrodesiccation and [[curettage]], [[Surgery|surg]]<nowiki/>ical excision, mohs micrographic surgery, and [[cryosurgery]].


==Basal Cell Carcinoma Surgery==
==Basal Cell Carcinoma Surgery==
Types of surgery for basal cell carcinoma involve electrodesiccation and curettage, surgical excision, mohs micrographic surgery, and cryosurgery.
* Types of [[surgery]] for basal cell carcinoma involve electrodesiccation and [[curettage]], [[Surgery|surgical]] [[excision]], [[mohs micrographic surgery]], and [[cryosurgery]].<ref name="pmid14525881">{{cite journal |vauthors=Wong CS, Strange RC, Lear JT |title=Basal cell carcinoma |journal=BMJ |volume=327 |issue=7418 |pages=794–8 |date=October 2003 |pmid=14525881 |pmc=214105 |doi=10.1136/bmj.327.7418.794 |url=}}</ref>


===Electrodesiccation and Curettage===
===Electrodesiccation and Curettage===
A curette is used to remove the tumor away from adjacent normal skin. Curetting is often followed by electrodesiccation, and the entire process may be repeated 1-2 more times. lectrodesiccation and curettage is a brief procedure and is effective in treating primary nodular and superficial basal cell carcinoma. The disadvantage of this procedure is it leaves a white, atrophic scar<ref name="pmid1820764">{{cite journal| author=Silverman MK, Kopf AW, Grin CM, Bart RS, Levenstein MJ|title=Recurrence rates of treated basal cell carcinomas. Part 2: Curettage-electrodesiccation. | journal=J Dermatol Surg Oncol | year= 1991 | volume= 17 | issue= 9 | pages= 720-6 | pmid=1820764 | doi= | pmc= |url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1820764  }} </ref>.
*It is the most widely used method for removing primary basal cell cancinoma's<ref name="pmid1820764">{{cite journal| author=Silverman MK, Kopf AW, Grin CM, Bart RS, Levenstein MJ|title=Recurrence rates of treated basal cell carcinomas. Part 2: Curettage-electrodesiccation. | journal=J Dermatol Surg Oncol | year= 1991 | volume= 17 | issue= 9 | pages= 720-6 | pmid=1820764 | doi= | pmc= |url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1820764  }} </ref>
*It is a 2 step [[Process (anatomy)|process]] which involves removal of the [[tumor]] by vigorously scraping it away from the adjacent normal [[skin]] first, followed by electrodesiccation later.
*This [[procedure]] goes well for [[nodular]] or [[superficial]] basal cell carcinoms, because these [[tumors]] tend to be friable and are not embedded in [[fibrous]] [[stroma]].
*The entire [[Process (anatomy)|process]] should be repeated for 1-2 more times.
*The [[surgeon]] should be extremely cautious while performing scraping in several directions, because many recurrences after [[curettage]] are believed to be due to insufficient [[aggressiveness]] on the part of the [[surgeon]].


===Surgical Excision===
===Surgical Excision===
Surgical excision is performed to remove and examine the specimen under a microscope. The larger mount of skin that is removed, the higher the cure rate. Normally, 3-4 mm margins of normal skin are removed. Although surgical excision is more time-consuming and costly compared to curettage, it produces cure rates as high as 95%<ref name="pmid9723063">{{cite journal| author=Grabski WJ, Salasche SJ| title=Positive surgical excision margins of a basal cell carcinoma. |journal=Dermatol Surg | year= 1998 | volume= 24 | issue= 8 | pages= 921-4 | pmid=9723063 | doi= | pmc= |url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9723063  }} </ref>.
Surgical [[excision]] is performed to remove and examine the specimen under a [[microscope]]. The larger mount of [[skin]] that is removed, the higher the [[cure]] rate. Normally, 3-4 mm margins of normal [[skin]] are removed. Although surgical [[excision]] is more time-consuming and costly compared to [[curettage]], it produces [[cure]] rates as high as 95%<ref name="pmid9723063">{{cite journal| author=Grabski WJ, Salasche SJ| title=Positive surgical excision margins of a basal cell carcinoma. |journal=Dermatol Surg | year= 1998 | volume= 24 | issue= 8 | pages= 921-4 | pmid=9723063 | doi= | pmc= |url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9723063  }} </ref>.


===Mohs Micrographic Surgery===
===Mohs Micrographic Surgery===
Mohs surgery involves removal of the tumor and a thin rim of normal-appearing skin<ref name="pmid15270883">{{cite journal| author=Smeets NW, Kuijpers DI, Nelemans P, Ostertag JU, Verhaegh ME, Krekels GA et al.| title=Mohs' micrographic surgery for treatment of basal cell carcinoma of the face--results of a retrospective study and review of the literature. | journal=Br J Dermatol | year= 2004 | volume= 151 | issue= 1 | pages= 141-7 | pmid=15270883 | doi=10.1111/j.1365-2133.2004.06047.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15270883  }} </ref>. Mohs micrographic surgery is indicated for the following:
*It is a [[procedure]] involving removal of visible [[lesion]] on the [[skin]] in several steps<ref name="pmid15270883">{{cite journal| author=Smeets NW, Kuijpers DI, Nelemans P, Ostertag JU, Verhaegh ME, Krekels GA et al.| title=Mohs' micrographic surgery for treatment of basal cell carcinoma of the face--results of a retrospective study and review of the literature. | journal=Br J Dermatol | year= 2004 | volume= 151 | issue= 1 | pages= 141-7 | pmid=15270883 | doi=10.1111/j.1365-2133.2004.06047.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15270883  }} </ref>.  
*Tumors with poorly defined clinical borders
*First we should remove a very thin layer and later we remove the next layer and view under the [[microscope]].
*Tumors with diameters > 1 cm located anywhere on the face
*We should keep on repeating the same [[procedure]] until no [[cancerous]] [[tissue]] is remaining.
*Tumors with diameters > 2 cm located in areas other than the face
[[Mohs micrographic surgery]] is indicated for the following:
*Tumors with infiltrative or morpheaform/sclerotic histopathologic patterns
*[[Tumors]] with poorly defined [[clinical]] borders
*Tumors arising in regions where a good cosmetic outcome is important
*[[Tumors]] with diameters > 1 cm located anywhere on the [[face]]
*[[Tumors]] with diameters > 2 cm located in areas other than the [[face]]
*[[Tumors]] with infiltrative or morpheaform/sclerotic [[histopathologic]] patterns
*[[Tumors]] arising in regions where a good cosmetic outcome is important


===Cryosurgery===
===Cryosurgery===
Cryosurgery may be considered for small, clinically well-defined primary tumors. This procedure is especially useful for patients who are debilitated with medical conditions. Liquid nitrogen is applied to the tumor, the treatment stops when the temperature reaches -60°C<ref name="pmid17642878">{{cite journal| author=Kaur S, Thami GP, Kanwar AJ| title=Basal cell carcinoma--treatment with cryosurgery. | journal=Indian J Dermatol Venereol Leprol | year= 2003 | volume= 69 | issue= 2 |pages= 188-90 | pmid=17642878 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17642878  }} </ref>.
[[Cryosurgery]] may be considered for small, [[clinical]]<nowiki/>ly well-defined primary [[tumors]]. This [[procedure]] is especially useful for [[patients]] who are debilitated with [[medical]] conditions. [[Liquid nitrogen]] is applied to the [[tumor]], the treatment stops when the [[temperature]] reaches -60°C<ref name="pmid17642878">{{cite journal| author=Kaur S, Thami GP, Kanwar AJ| title=Basal cell carcinoma--treatment with cryosurgery. | journal=Indian J Dermatol Venereol Leprol | year= 2003 | volume= 69 | issue= 2 |pages= 188-90 | pmid=17642878 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17642878  }} </ref>.


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}


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[[Category:Oncology]]

Latest revision as of 11:44, 12 March 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Saarah T. Alkhairy, M.D., Maneesha Nandimandalam, M.B.B.S.[2]

Overview

Types of surgery for basal cell carcinoma involve electrodesiccation and curettage, surgical excision, mohs micrographic surgery, and cryosurgery.

Basal Cell Carcinoma Surgery

Electrodesiccation and Curettage

  • It is the most widely used method for removing primary basal cell cancinoma's[2]
  • It is a 2 step process which involves removal of the tumor by vigorously scraping it away from the adjacent normal skin first, followed by electrodesiccation later.
  • This procedure goes well for nodular or superficial basal cell carcinoms, because these tumors tend to be friable and are not embedded in fibrous stroma.
  • The entire process should be repeated for 1-2 more times.
  • The surgeon should be extremely cautious while performing scraping in several directions, because many recurrences after curettage are believed to be due to insufficient aggressiveness on the part of the surgeon.

Surgical Excision

Surgical excision is performed to remove and examine the specimen under a microscope. The larger mount of skin that is removed, the higher the cure rate. Normally, 3-4 mm margins of normal skin are removed. Although surgical excision is more time-consuming and costly compared to curettage, it produces cure rates as high as 95%[3].

Mohs Micrographic Surgery

  • It is a procedure involving removal of visible lesion on the skin in several steps[4].
  • First we should remove a very thin layer and later we remove the next layer and view under the microscope.
  • We should keep on repeating the same procedure until no cancerous tissue is remaining.

Mohs micrographic surgery is indicated for the following:

  • Tumors with poorly defined clinical borders
  • Tumors with diameters > 1 cm located anywhere on the face
  • Tumors with diameters > 2 cm located in areas other than the face
  • Tumors with infiltrative or morpheaform/sclerotic histopathologic patterns
  • Tumors arising in regions where a good cosmetic outcome is important

Cryosurgery

Cryosurgery may be considered for small, clinically well-defined primary tumors. This procedure is especially useful for patients who are debilitated with medical conditions. Liquid nitrogen is applied to the tumor, the treatment stops when the temperature reaches -60°C[5].

References

  1. Wong CS, Strange RC, Lear JT (October 2003). "Basal cell carcinoma". BMJ. 327 (7418): 794–8. doi:10.1136/bmj.327.7418.794. PMC 214105. PMID 14525881.
  2. Silverman MK, Kopf AW, Grin CM, Bart RS, Levenstein MJ (1991). "Recurrence rates of treated basal cell carcinomas. Part 2: Curettage-electrodesiccation". J Dermatol Surg Oncol. 17 (9): 720–6. PMID 1820764.
  3. Grabski WJ, Salasche SJ (1998). "Positive surgical excision margins of a basal cell carcinoma". Dermatol Surg. 24 (8): 921–4. PMID 9723063.
  4. Smeets NW, Kuijpers DI, Nelemans P, Ostertag JU, Verhaegh ME, Krekels GA; et al. (2004). "Mohs' micrographic surgery for treatment of basal cell carcinoma of the face--results of a retrospective study and review of the literature". Br J Dermatol. 151 (1): 141–7. doi:10.1111/j.1365-2133.2004.06047.x. PMID 15270883.
  5. Kaur S, Thami GP, Kanwar AJ (2003). "Basal cell carcinoma--treatment with cryosurgery". Indian J Dermatol Venereol Leprol. 69 (2): 188–90. PMID 17642878.

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