Basal cell carcinoma staging

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Saarah T. Alkhairy, M.D.

Overview

The American Joint Committee on Cancer (AJCC) stages basal cell carcinoma based on the TNM system. T, M, and N are combined into stages, called stage grouping.

Basal Cell Carcinoma Staging

The American Joint Committee on Cancer (AJCC) stages basal cell carcinoma based on the TNM system:
T - tumor
N - lymph nodes
M - metastasis

The following table summarizes the T categories:

T Categories Description
Tis Carcinoma in situ
T1 The tumor is blank 2 cm across AND has 0-1 high-risk features
T2 The tumor is > 2 cm across AND has > 2 high-risk features
T3 The tumor has grown into facial bones
T4 The tumor has grown into other bones in the body or into the base of the skull

The following table summarizes the N categories:

N categories Description
N0 The tumor has not spread to the lymph nodes
N1 The tumor has spread to 1 lymph node on the same side of the body as the main tumor AND is ≤ 3 cm across
N2a The tumor has spread to 1 lymph node on the same side of the body as the main tumor AND is > 3 cm and ≤ 6 cm across
N2b The tumor has spread to > 1 lymph node on the same side of the body as the main tumor AND is ≤ 6 cm across
N2c The tumor has spread to > 1 lymph node on the other side of the body as the main tumor AND is ≤ 6 cm across
N3 The tumor has spread to any nearby lymph node AND is > 6 cm across

The following table summarizes the M categories:

M categories Description
M0 The tumor has not spread to distant organs
M1 The tumor has spread to distant organs

The T, N, and M categories are combined into stages. The following table summarizes the stage grouping.

Stage TNM Grouping
0 Tis, N0, M0
I T1, N0, M0
II T2, N0, M0
III T3, N0, M0; T1-T3, N1, M0
IV T1-T3, N2, M0; Any T, N3, M0; T4, any N, M0; Any T, any N, M1

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