Basal cell carcinoma laboratory tests: Difference between revisions

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{{Basal cell carcinoma}}
{{Basal cell carcinoma}}
{{CMG}}
{{CMG}} {{AE}} Saarah T. Alkhairy, M.D.
 
==Overview==
==Overview==
To diagnose basal cell carcinomas, a [[biopsy]] (where tissue is taken for pathological study) is done using local anesthesia. In small lesions, the tumor is generally removed in its entiriety, while larger ones are biopsied first and surgically removed later if it is confirmed that it is malignant.
The laboratory tests of basal cell carcinoma are a biopsy and its histological findings.
 
==Basal cell Carcinoma Laboratory Tests==
 
===Biopsy===
A skin biopsy can prove the diagnosis of basal cell carcinoma. An excisional or punch biopsy can visualize the depth of the tumor.


==Histopathology==
 
Basal cell carcinoma is a malignant epithelial tumor arising only in skin, from the basal layer of the epidermis or of the pilosebaceous adnexa. Tumor is represented by compact areas, well delineated and invading the dermis, apparent with no connection with the epidermis. Tumor cells resemble normal basal cells (small, monomorphous) are disposed in palisade at the periphery of the tumor nests, but are spindle-shaped and irregular in the middle. Tumor clusters are separated by a reduced stroma with inflammatory infiltrate.
====Histology Findings====
Several histologic types of basal cell carcinoma exist.
 
The following are aggressive histological types:
*Basosquamous
*Micronodular
*Infiltrative
*Sclerosing
*Morpheaform (desmoplastic)
 
The following are non-aggressive histological types:
*Keratotic variant
*Infundibulocystic variant
*Fibroepithelioma of Pinkus


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
[[pl:Rak podstawnokomórkowy skóry]]
[[pt:Carcinoma basocelular]]
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{{WikiDoc Sources}}


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[[Category:Pathology]]
[[Category:Pathology]]
[[Category:Oncology]]
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Revision as of 17:35, 24 July 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Saarah T. Alkhairy, M.D.

Overview

The laboratory tests of basal cell carcinoma are a biopsy and its histological findings.

Basal cell Carcinoma Laboratory Tests

Biopsy

A skin biopsy can prove the diagnosis of basal cell carcinoma. An excisional or punch biopsy can visualize the depth of the tumor.


Histology Findings

Several histologic types of basal cell carcinoma exist.

The following are aggressive histological types:

  • Basosquamous
  • Micronodular
  • Infiltrative
  • Sclerosing
  • Morpheaform (desmoplastic)

The following are non-aggressive histological types:

  • Keratotic variant
  • Infundibulocystic variant
  • Fibroepithelioma of Pinkus

References


Template:WikiDoc Sources