Balsalazide: Difference between revisions
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==Overview== | ==Overview== | ||
'''Balsalazide''' is an anti-inflammatory drug used in the treatment of [[Inflammatory Bowel Disease]]. It is sold under the name "Colazal" in the US and "Colazide" in the UK. | '''Balsalazide''' is an anti-inflammatory drug used in the treatment of [[Inflammatory Bowel Disease]]. It is sold under the name "Colazal" in the US and "Colazide" in the UK. | ||
Revision as of 22:44, 8 August 2012
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| Clinical data | |
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| ATC code | |
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| Legal status |
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| Pharmacokinetic data | |
| Bioavailability | <1% |
| Protein binding | ≥99% |
| Elimination half-life | 12hr |
| Identifiers | |
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| PubChem CID | |
| DrugBank | |
| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C17H15N3O6 |
| Molar mass | 357.318 g/mol |
Overview
Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK.
The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt.
Balsalazide releases mesalazine, also known as 5-aminosalicylic acid, or 5-ASA, in the large intestine. Its advantage over that drug in the treatment of Ulcerative colitis is believed to be the delivery of the active agent past the small intestine to the large intestine, the active site of ulcerative colitis.
External links
Template:Antidiarrheals, intestinal anti-inflammatory/anti-infective agents Template:Jb1
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