BPI fold-containing family B member 2
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BPI fold-containing family B member 2 (BPIFB2) also known as bactericidal/permeability-increasing protein-like 1 (BPI-like 1) is a protein that in humans is encoded by the BPIFB2 gene.[1][2]
Function
This gene encodes a member of the lipid transfer/lipopolysaccharide binding protein (LT/LBP) gene family. It is highly expressed in hypertrophic tonsils. This gene and three other members of the LT/LBP gene family form a cluster on the long arm of chromosome 20.[2]
References
- ↑ Mulero JJ, Boyle BJ, Bradley S, Bright JM, Nelken ST, Ho TT, Mize NK, Childs JD, Ballinger DG, Ford JE, Rupp F (Aug 2002). "Three new human members of the lipid transfer/lipopolysaccharide binding protein family (LT/LBP)". Immunogenetics. 54 (5): 293–300. doi:10.1007/s00251-002-0467-3. PMID 12185532.
- ↑ 2.0 2.1 "Entrez Gene: BPIL1 bactericidal/permeability-increasing protein-like 1".
External links
- Human BPIFB2 genome location and BPIFB2 gene details page in the UCSC Genome Browser.
Further reading
- Bingle CD, Bingle L (2000). "Characterisation of the human plunc gene, a gene product with an upper airways and nasopharyngeal restricted expression pattern". Biochim. Biophys. Acta. 1493 (3): 363–7. doi:10.1016/S0167-4781(00)00196-2. PMID 11018263.
- Bingle CD, Craven CJ (2003). "PLUNC: a novel family of candidate host defence proteins expressed in the upper airways and nasopharynx". Hum. Mol. Genet. 11 (8): 937–43. doi:10.1093/hmg/11.8.937. PMID 11971875.
- Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
- Ramachandran P, Boontheung P, Xie Y, et al. (2006). "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry". J. Proteome Res. 5 (6): 1493–503. doi:10.1021/pr050492k. PMID 16740002.
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