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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{Infobox_gene}}
{{GNF_Protein_box
'''BET1 homolog''' is a [[protein]] that in humans is encoded by the ''BET1'' [[gene]].<ref name="pmid9382863">{{cite journal | vauthors = Zhang T, Wong SH, Tang BL, Xu Y, Peter F, Subramaniam VN, Hong W | title = The mammalian protein (rbet1) homologous to yeast Bet1p is primarily associated with the pre-Golgi intermediate compartment and is involved in vesicular transport from the endoplasmic reticulum to the Golgi apparatus | journal = J Cell Biol | volume = 139 | issue = 5 | pages = 1157–68 |date=Dec 1997 | pmid = 9382863 | pmc = 2140212 | doi =10.1083/jcb.139.5.1157  }}</ref><ref name="pmid10449330">{{cite journal | vauthors = Waters MG, Pfeffer SR | title = Membrane tethering in intracellular transport | journal = Curr Opin Cell Biol | volume = 11 | issue = 4 | pages = 453–9 |date=Nov 1999 | pmid = 10449330 | pmc = | doi =10.1016/S0955-0674(99)80065-9 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: BET1 BET1 homolog (S. cerevisiae)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10282| accessdate = }}</ref>
| image = 
| image_source = 
| PDB =
| Name = BET1 homolog (S. cerevisiae)
| HGNCid = 14562
| Symbol = BET1
| AltSymbols =; DKFZp781C0425; HBET1
| OMIM = 605456
| ECnumber = 
| Homologene = 38108
| MGIid = 1343104
| GeneAtlas_image1 = PBB_GE_BET1_202710_at_tn.png
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0000139 |text = Golgi membrane}} {{GNF_GO|id=GO:0005783 |text = endoplasmic reticulum}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0006888 |text = ER to Golgi vesicle-mediated transport}} {{GNF_GO|id=GO:0015031 |text = protein transport}}  
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 10282
    | Hs_Ensembl = ENSG00000105829
    | Hs_RefseqProtein = NP_005859
    | Hs_RefseqmRNA = NM_005868
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 7
    | Hs_GenLoc_start = 93430021
    | Hs_GenLoc_end = 93471626
    | Hs_Uniprot = O15155
    | Mm_EntrezGene = 12068
    | Mm_Ensembl = ENSMUSG00000032757
    | Mm_RefseqmRNA = NM_009748
    | Mm_RefseqProtein = NP_033878
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 6
    | Mm_GenLoc_start = 4026904
    | Mm_GenLoc_end = 4036927
    | Mm_Uniprot = Q8BNZ1
  }}
}}
'''BET1 homolog (S. cerevisiae)''', also known as '''BET1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: BET1 BET1 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10282| accessdate = }}</ref>


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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = This gene encodes a golgi-associated membrane protein that participates in vesicular transport from the endoplasmic reticulum (ER) to the Golgi complex. The encoded protein functions as a soluble N-ethylaleimide-sensitive factor attachment protein receptor and may be involved in the docking of ER-derived vesicles with the cis-Golgi membrane. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has not been determined.<ref name="entrez">{{cite web | title = Entrez Gene: BET1 BET1 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10282| accessdate = }}</ref>
| summary_text = This gene encodes a golgi-associated membrane protein that participates in [[vesicular transport]] from the [[endoplasmic reticulum]] (ER) to the [[Golgi complex]]. The encoded protein functions as a soluble N-ethylaleimide-sensitive factor attachment [[protein receptor]] and may be involved in the docking of ER-derived vesicles with the cis-Golgi membrane. Alternatively spliced transcript variants encoding different [[isoforms]] have been described but their full-length nature has not been determined.<ref name="entrez"/>
}}
}}


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Waters MG, Pfeffer SR |title=Membrane tethering in intracellular transport. |journal=Curr. Opin. Cell Biol. |volume=11 |issue= 4 |pages= 453-9 |year= 1999 |pmid= 10449330 |doi=  }}
*{{cite journal  | vauthors=Olsen JV, Blagoev B, Gnad F |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |display-authors=etal}}
*{{cite journal  | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal  | vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |display-authors=etal}}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | vauthors=Hillier LW, Fulton RS, Fulton LA |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 |display-authors=etal}}
*{{cite journal  | author=Hillier LW, Fulton RS, Fulton LA, ''et al.'' |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157-64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 }}
*{{cite journal  | vauthors=Scherer SW, Cheung J, MacDonald JR |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 | pmc=2882961 |doi= 10.1126/science.1083423 |display-authors=etal}}
*{{cite journal  | author=Scherer SW, Cheung J, MacDonald JR, ''et al.'' |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767-72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Zhang T, Hong W |title=Ykt6 forms a SNARE complex with syntaxin 5, GS28, and Bet1 and participates in a late stage in endoplasmic reticulum-Golgi transport. |journal=J. Biol. Chem. |volume=276 |issue= 29 |pages= 27480–7 |year= 2001 |pmid= 11323436 |doi= 10.1074/jbc.M102786200 }}
*{{cite journal  | author=Zhang T, Hong W |title=Ykt6 forms a SNARE complex with syntaxin 5, GS28, and Bet1 and participates in a late stage in endoplasmic reticulum-Golgi transport. |journal=J. Biol. Chem. |volume=276 |issue= 29 |pages= 27480-7 |year= 2001 |pmid= 11323436 |doi= 10.1074/jbc.M102786200 }}
*{{cite journal  |title=Toward a complete human genome sequence. |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097–108 |year= 1999 |pmid= 9847074 |doi=  10.1101/gr.8.11.1097}}
*{{cite journal  | author= |title=Toward a complete human genome sequence. |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097-108 |year= 1999 |pmid= 9847074 |doi=  }}
*{{cite journal  | vauthors=Hay JC, Chao DS, Kuo CS, Scheller RH |title=Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells. |journal=Cell |volume=89 |issue= 1 |pages= 149–58 |year= 1997 |pmid= 9094723 |doi=10.1016/S0092-8674(00)80191-9 }}
*{{cite journal  | author=Zhang T, Wong SH, Tang BL, ''et al.'' |title=The mammalian protein (rbet1) homologous to yeast Bet1p is primarily associated with the pre-Golgi intermediate compartment and is involved in vesicular transport from the endoplasmic reticulum to the Golgi apparatus. |journal=J. Cell Biol. |volume=139 |issue= 5 |pages= 1157-68 |year= 1997 |pmid= 9382863 |doi=  }}
*{{cite journal  | vauthors=Hay JC, Hirling H, Scheller RH |title=Mammalian vesicle trafficking proteins of the endoplasmic reticulum and Golgi apparatus. |journal=J. Biol. Chem. |volume=271 |issue= 10 |pages= 5671–9 |year= 1996 |pmid= 8621431 |doi=10.1074/jbc.271.10.5671 }}
*{{cite journal  | author=Hay JC, Chao DS, Kuo CS, Scheller RH |title=Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells. |journal=Cell |volume=89 |issue= 1 |pages= 149-58 |year= 1997 |pmid= 9094723 |doi=  }}
*{{cite journal  | author=Hay JC, Hirling H, Scheller RH |title=Mammalian vesicle trafficking proteins of the endoplasmic reticulum and Golgi apparatus. |journal=J. Biol. Chem. |volume=271 |issue= 10 |pages= 5671-9 |year= 1996 |pmid= 8621431 |doi=  }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
==External links==
{{WikiDoc Sources}}
* {{UCSC genome browser|BET1}}
* {{UCSC gene details|BET1}}
 
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{{gene-7-stub}}

Latest revision as of 13:37, 14 February 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

BET1 homolog is a protein that in humans is encoded by the BET1 gene.[1][2][3]

This gene encodes a golgi-associated membrane protein that participates in vesicular transport from the endoplasmic reticulum (ER) to the Golgi complex. The encoded protein functions as a soluble N-ethylaleimide-sensitive factor attachment protein receptor and may be involved in the docking of ER-derived vesicles with the cis-Golgi membrane. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has not been determined.[3]

References

  1. ↑ Zhang T, Wong SH, Tang BL, Xu Y, Peter F, Subramaniam VN, Hong W (Dec 1997). "The mammalian protein (rbet1) homologous to yeast Bet1p is primarily associated with the pre-Golgi intermediate compartment and is involved in vesicular transport from the endoplasmic reticulum to the Golgi apparatus". J Cell Biol. 139 (5): 1157–68. doi:10.1083/jcb.139.5.1157. PMC 2140212. PMID 9382863.
  2. ↑ Waters MG, Pfeffer SR (Nov 1999). "Membrane tethering in intracellular transport". Curr Opin Cell Biol. 11 (4): 453–9. doi:10.1016/S0955-0674(99)80065-9. PMID 10449330.
  3. ↑ 3.0 3.1 "Entrez Gene: BET1 BET1 homolog (S. cerevisiae)".

Further reading

External links



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