Aspergilloma: Difference between revisions

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== Clinical syndrome ==
Typically, individuals who are affected by aspergillomas do not have [[symptom]]s related to the infestation. People often co-exist for decades with aspergillomas prior to incidental [[diagnosis]], typically by [[x-ray]] or [[computed tomography]]. However, a small percentage of aspergillomas invade into the wall of the cavity and can result in bleeding. Thus, the most common symptom of aspergillomas is [[cough]]ing up blood ([[hemoptysis]]). Although this can occasionally be life-threatening, the amount of blood produced is usually inconsequential.
 
Aspergillomas can form in other body cavities. Aspergillus can form [[abscess]]es in the brain, usually in people who are immunocompromised. They can also form within the different [[Paranasal sinus|sinuses]] in the face, within the [[kidney]]s and [[urinary system]], the [[ear canal]], and  on the [[heart valve]]s.
 
==Diagnosis==
The imaging findings are
* Intracavitary mass
* Usually in upper lobes
* Air may surround aspergilloma (Monod sign). This is not to be confused with the Air crescent sign seen with invasive apergillosis
* Moves with changing positions
* Adjacent pleural thickening is common
 
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== Treatment ==
Most cases of aspergilloma do not require treatment. Treatment of diseases which increase the risk of aspergilloma, such as tuberculosis, may help prevent their formation. In cases complicated by severe hemoptysis, [[surgery]] may be required to remove the aspergilloma and stop the bleeding. There has been interest in treatment with anti-fungal [[medication]]s such as [[itraconazole]], but as of [[2005]], none has been shown to eradicate aspergillomas.
 
== References ==
*Soubani AO, Chandrasekar PH. ''The clinical spectrum of pulmonary aspergillosis.'' Chest. 2002 Jun;121(6):1988-99. Review. PMID 12065367
 
 
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[[Category:Pulmonology]]
 
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Latest revision as of 00:46, 9 February 2016

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